{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T01:15:14Z","timestamp":1781658914716,"version":"3.54.5"},"reference-count":18,"publisher":"Mark Allen Group","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nurs"],"published-print":{"date-parts":[[2008,5,1]]},"abstract":"<jats:p> Fabry disease is an inherited, progressive, life-threatening disease; therefore, lifelong therapy is needed. By replacing the deficient enzyme, disease progression may be delayed or halted, thereby avoiding serious complications. Hospital-based agalsidase therapy is generally perceived as inconvenient and home-based infusion therapy is greatly appreciated by patients, their families and healthcare professionals. Patients can get familiar with infusion therapy in a hospital setting and, if specific requirements are fulfilled, routine nurse-assisted infusion, or self-care, at the patient\u2019s home can be organized. A stable patient who tolerates the infusion and a suitable home environment are prerequisites for home therapy. The authors\u2019 clinical experiences underscore the safety and practicality of home therapy. In addition to a major positive impact on the patient\u2019s quality of life, home infusion therapy may reduce the constraints of hospital resources. This article reviews the collective experiences with agalsidase beta home infusion therapy and outlines how safe, patient-centred homecare can be organized. Home infusion therapy with Fabrazyme\u00aeshould not be withheld from patients considered eligible according to the proposed criteria. Similar approaches to other enzyme therapies are also possible. <\/jats:p>","DOI":"10.12968\/bjon.2008.17.10.29481","type":"journal-article","created":{"date-parts":[[2014,5,23]],"date-time":"2014-05-23T14:12:11Z","timestamp":1400854331000},"page":"653-657","source":"Crossref","is-referenced-by-count":20,"title":["Home-based infusion therapy for patients with Fabry disease"],"prefix":"10.12968","volume":"17","author":[{"given":"Alison","family":"Cousins","sequence":"first","affiliation":[{"name":"Charles Dent Metabolic Unit, National Hospital for Neurology and Neurosurgery, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Lee","sequence":"additional","affiliation":[{"name":"Charles Dent Metabolic Unit, National Hospital for Neurology and Neurosurgery, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Rorman","sequence":"additional","affiliation":[{"name":"Zur Hadassah Medical Clinic, Zur Hadassah, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annick","family":"Raas-Rothschild","sequence":"additional","affiliation":[{"name":"Department of Human Genetics, Hadassah-Hebrew University Hospital, Ein Kerem, Jerusalem, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Banikazemi","sequence":"additional","affiliation":[{"name":"Department of Neurology, New York University School of Medicine, New York, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve","family":"Waldek","sequence":"additional","affiliation":[{"name":"Adult Inherited Metabolic Diseases Department, Salford Royal NHS Foundation Trust, Salford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorraine","family":"Thompson","sequence":"additional","affiliation":[{"name":"Adult Inherited Metabolic Diseases Department, Salford Royal NHS Foundation Trust, Salford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5130","reference":[{"key":"p_23","volume-title":"55th Annual Meeting, Salt Lake City, October 26-8","author":"Banikazemi M"},{"key":"p_24","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-146-2-200701160-00148"},{"issue":"170","key":"p_25","first-page":"335","volume":"27","author":"Cole A","year":"2004","journal-title":"J Inherit Metab Dis"},{"key":"p_26","doi-asserted-by":"publisher","DOI":"10.1007\/s10545-007-0686-8"},{"key":"p_27","volume-title":"The Metabolic and Molecular Bases of Inherited Disease","author":"Desnick RJ","edition":"8"},{"key":"p_28","doi-asserted-by":"publisher","DOI":"10.1097\/01.gim.0000237866.70357.c6"},{"key":"p_29","doi-asserted-by":"publisher","DOI":"10.1086\/318809"},{"key":"p_30","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200107053450102"},{"key":"p_31","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2006080816"},{"key":"p_32","doi-asserted-by":"publisher","DOI":"10.1023\/A:1015511908710"},{"key":"p_33","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2004.00924.x"},{"key":"p_34","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfi221"},{"key":"p_35","doi-asserted-by":"publisher","DOI":"10.1001\/jama.281.3.249"},{"key":"p_36","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200767180-00005"},{"key":"p_37","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2004.01.049"},{"key":"p_38","doi-asserted-by":"publisher","DOI":"10.1086\/422366"},{"key":"p_39","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2007.09.013"},{"issue":"4","key":"p_40","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1182\/blood.V82.4.1107.1107","volume":"82","author":"Zimran A","year":"1993","journal-title":"Blood"}],"container-title":["British Journal of Nursing"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/bjon.2008.17.10.29481","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T20:17:30Z","timestamp":1653337050000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/bjon.2008.17.10.29481"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5,1]]},"references-count":18,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["10.12968\/bjon.2008.17.10.29481"],"URL":"https:\/\/doi.org\/10.12968\/bjon.2008.17.10.29481","relation":{},"ISSN":["0966-0461","2052-2819"],"issn-type":[{"value":"0966-0461","type":"print"},{"value":"2052-2819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,5,1]]}}}