{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T23:48:55Z","timestamp":1769557735517,"version":"3.49.0"},"reference-count":20,"publisher":"Mark Allen Group","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nurs"],"published-print":{"date-parts":[[2018,4,26]]},"abstract":"<jats:p> Totally implantable venous access device (TIVAD) lumen occlusion is a long-term complication of central venous catheters, associated with risks of infection, therapy interruptions and increased healthcare costs. The role of flushing and locking in maintaining TIVAD patency is paramount. Most flushing protocols are based on manufacturers' recommendations, which indicate that 4 weeks is the safest interval between two consecutive flushing procedures during periods when TIVADs are not in use. Conversely, results of several studies suggest that extended flushing intervals (FIs) do not increase the rate of obstructive or infective complications. The study aimed to describe the effects of prolonged FIs in a cohort of 317 patients with cancer. The authors found no significant difference in terms of TIVAD problems between long (&gt;45 days) and short (\u226445 days) FI groups, which raises questions over the validity of current practice. <\/jats:p>","DOI":"10.12968\/bjon.2018.27.8.s4","type":"journal-article","created":{"date-parts":[[2018,4,23]],"date-time":"2018-04-23T17:26:05Z","timestamp":1524504365000},"page":"S4-S10","source":"Crossref","is-referenced-by-count":14,"title":["Effects of prolonged flushing interval in totally implantable venous access devices (TIVADs)"],"prefix":"10.12968","volume":"27","author":[{"given":"Laura","family":"Rasero","sequence":"first","affiliation":[{"name":"Associate Professor, Department of Health Science, University of Florence, Careggi Teaching Hospital, Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Golin","sequence":"additional","affiliation":[{"name":"Nurse, Oncology Outpatient Clinic, Careggi Teaching Hospital, Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serena","family":"Ditta","sequence":"additional","affiliation":[{"name":"Nurse, Independent Contractor, Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dino Stefano Di","family":"Massimo","sequence":"additional","affiliation":[{"name":"Nurse, Department of Oncology, Biella Hospital, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto Dal","family":"Molin","sequence":"additional","affiliation":[{"name":"Nurse Researcher, Department of Translational Medicine, University of Piemonte Orientale, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guya","family":"Piemonte","sequence":"additional","affiliation":[{"name":"Nurse and PhD Student, Department of Health Science, University of Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5130","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1188\/07.CJON.485-488"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2010.11.007"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.5301\/jva.5000225"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2015.04.001"},{"key":"B5","first-page":"379","volume":"7","author":"Ferroni A","year":"2014","journal-title":"Med Devices (Auckl)"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.3322\/CA.2008.0015"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdt114"},{"key":"B8","first-page":"985686","volume":"2015","author":"Goossens GA.","year":"2015","journal-title":"Nurs Res Pract"},{"key":"B9","first-page":"S1","volume":"39","author":"Gorski LA","year":"2016","journal-title":"J Infus Nurs"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1159\/000294919"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2354.2008.00973.x"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1080\/07357900500276923"},{"issue":"10","key":"B13","first-page":"CD008462","author":"L\u00f3pez-Briz E","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.4065\/81.9.1159"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2648.2009.05103.x"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1017\/S0195941700080577"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2013.09.002"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.5301\/jva.5000576"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.5301\/jva.5000740"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdm272"}],"container-title":["British Journal of Nursing"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/bjon.2018.27.8.S4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T21:04:47Z","timestamp":1653426287000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/bjon.2018.27.8.S4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,26]]},"references-count":20,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,4,26]]}},"alternative-id":["10.12968\/bjon.2018.27.8.S4"],"URL":"https:\/\/doi.org\/10.12968\/bjon.2018.27.8.s4","relation":{},"ISSN":["0966-0461","2052-2819"],"issn-type":[{"value":"0966-0461","type":"print"},{"value":"2052-2819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,26]]}}}