{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:34:43Z","timestamp":1762508083315},"reference-count":26,"publisher":"Mark Allen Group","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nurs"],"published-print":{"date-parts":[[2020,4,23]]},"abstract":"HIGHLIGHTS<\/jats:title> A lower central venous catheter (CVC) infection rate suggests an improvement in practice and education. CVC infection remains a complication that often requires significant health care resources. Use of tunneled CVC and patient education on catheter care reduces CVC infection rates. <\/jats:p><\/jats:sec>Objectives:<\/jats:title> CVC infection is one of the most frequent, life-threatening complications in home parenteral nutrition (HPN) patients. Our objective was to conduct a 5-year retrospective chart review regarding CVC infections in 3 adult HPN programs. <\/jats:p><\/jats:sec>Methods:<\/jats:title> Data were collected from the Canadian HPN Registry and patient charts that include demography, infection diagnosis, blood cultures, and treatments. <\/jats:p><\/jats:sec>Results:<\/jats:title> Results are reported as median (range) \u00b1 standard error of mean or population frequency. Eighty-one charts were reviewed. Mean age was 51.98 \u00b1 1.71 years. Short bowel syndrome (54.3%) was the primary diagnosis, with 36 months (range, 1324 months) median length of HPN therapy. Forty-seven subjects (58%) had infections over a 5-year period. Of these, there were 144 sepsis events. There was positive correlation (r=0.423; P<0.001) between number of infections and HPN duration. The median length of time the CVC was in place was 281 (range, 14\u20134380) days. There were 66.7% tunneled CVCs; 25.9% peripherally inserted central catheters (PICCs), and 7.4% implanted venous port. In this sample, there was no association between line infection and catheter type. Most patients presented with fever (58.3%) and chills (38.2%). Blood cultures were done (89.6%), and coagulase negative Staphylococcus was the resulting pathogen present in 25.7%. Patients with bloodstream infection were treated for 17.9 \u00b1 1.2 days with combination antibiotics (22.2%). Overall, the CVC infection rate was 0.97 per 1000 catheter days. <\/jats:p><\/jats:sec>Conclusion:<\/jats:title> We found the standard approach to infection prevention is comparable to reports in literature. However, a subset of patients with multiple CVC infections require education with an emphasis on preventive techniques in order to reduce the incidence of infection. <\/jats:p><\/jats:sec>","DOI":"10.12968\/bjon.2020.29.8.s34","type":"journal-article","created":{"date-parts":[[2020,4,23]],"date-time":"2020-04-23T18:23:01Z","timestamp":1587666181000},"page":"S34-S42","source":"Crossref","is-referenced-by-count":7,"title":["Central venous catheter infection in Canadian home parenteral nutrition patients: a 5-year multicenter retrospective study"],"prefix":"10.12968","volume":"29","author":[{"given":"Olivia","family":"Saqui","sequence":"first","affiliation":[{"name":"Toronto General Hospital, University Health Network, Toronto, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Toronto General Hospital, University Health Network, Toronto, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Allard","sequence":"additional","affiliation":[{"name":"Toronto General Hospital, University Health Network, Toronto, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5130","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2004.04.024"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.4065\/74.3.217"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1177\/0148607105029005367"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1177\/0148607105029006408"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.2309\/java.12-2-10"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1155\/2007\/217897"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1177\/014860710202600508"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1177\/01486071060300S1S57"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2016.01.020"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1177\/088453360101600105"},{"key":"B13","first-page":"569","volume":"123","author":"Singhal R","year":"2006","journal-title":"Indian J Med Res"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1054\/clnu.2002.0541"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1097\/01.RVI.0000121405.46920.87"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1002\/jpen.1455"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1177\/0115426505020005579"},{"key":"B18","first-page":"1","volume":"20","author":"Ayers P","year":"2013","journal-title":"J Parenter Enteral Nutr"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1177\/0148607103027002137"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmedinf.2006.09.024"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.9085"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.3109\/0142159X.2012.642831"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1177\/0148607102026003159"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1177\/01486071060300S1S5"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1177\/011542650602100156"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1023\/A:1005628121546"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(03)00326-3"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.09.064"}],"container-title":["British Journal of Nursing"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/bjon.2020.29.8.S34","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T23:31:31Z","timestamp":1653435091000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/bjon.2020.29.8.S34"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,23]]},"references-count":26,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,4,23]]}},"alternative-id":["10.12968\/bjon.2020.29.8.S34"],"URL":"https:\/\/doi.org\/10.12968\/bjon.2020.29.8.s34","relation":{},"ISSN":["0966-0461","2052-2819"],"issn-type":[{"value":"0966-0461","type":"print"},{"value":"2052-2819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,23]]}}}