{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T11:41:40Z","timestamp":1771674100938,"version":"3.50.1"},"reference-count":55,"publisher":"Mark Allen Group","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nurs"],"published-print":{"date-parts":[[2020,5,14]]},"abstract":"<jats:p>Transient loss of consciousness (TLOC) accounts for 3% of all attendance in emergency departments within the UK. More than 90% of TLOC presentations are due to epileptic seizures, psychogenic seizures or syncope. However, in England and Wales in 2002, it was estimated that 92 000 patients were incorrectly diagnosed with epilepsy, at an additional annual cost to the NHS of up to \u00a3189 million. This article will reflect on the case study of a 54-year-old female patient who presented with a possible TLOC, and had a background of long-term depression. Differential diagnoses will be discussed, but the article will focus on orthostatic hypotension. Being diagnosed with this condition is independently associated with an increased risk of all-cause mortality. Causes of orthostatic hypotension and the pathophysiology behind the condition will be discussed, highlighting the importance of obtaining an accurate clinical history. This is extremely pertinent if a patient collapses in an NHS setting and this is witnessed by nurses because they can contribute to the history of the type of collapse, to aid diagnosis and correct treatment. In addition, nurses have a valuable role to play in highlighting polypharmacy to doctors, and non-medical prescribers, as a contributing factor to orthostatic hypotension is polypharmacy. It is therefore important to accurately distinguish TLOC aetiology, not only to provide appropriate management, but to also identify patients at risk of morbidity\/mortality related to underlying disease.<\/jats:p>","DOI":"10.12968\/bjon.2020.29.9.506","type":"journal-article","created":{"date-parts":[[2020,5,14]],"date-time":"2020-05-14T17:29:19Z","timestamp":1589477359000},"page":"506-511","source":"Crossref","is-referenced-by-count":2,"title":["Orthostatic hypotension: clinical review and case study"],"prefix":"10.12968","volume":"29","author":[{"given":"Rachael","family":"Bailey","sequence":"first","affiliation":[{"name":"Trainee Advanced Clinical Practitioner, Department of Health and Social Care, University of Derby"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerri","family":"Mortimore","sequence":"additional","affiliation":[{"name":"Lecturer in Advanced Practice, Department of Health and Social Care, University of Derby"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5130","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-69269-2_4"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.12.065"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0075255"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2007.12.007"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy037"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.4103\/2230-8210.86860"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1681.2002.03640.x"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.07.047"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.4065\/79.7.890"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.110.151654"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1111\/joim.12021"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2011.02.004"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/aft213"},{"issue":"1","key":"B18","first-page":"CD008269","author":"Gibbons CH","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-137-9-200211050-00011"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.4330\/wjc.v7.i4.204"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.2165\/11591710-000000000-00000"},{"issue":"3","key":"B22","first-page":"164","volume":"18","author":"Hopson JR","year":"1993","journal-title":"Herz"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(00)00322-X"},{"key":"B24","unstructured":"Japp AG, Robertson C. Macleod's clinical diagnosis. 2nd edn. London: Elsevier; 2018"},{"key":"B25","unstructured":"Joint Formulary Committee. British National Formulary 76. London: BMJ Group and Pharmaceutical Press; 2018"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2006.08.005"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afp192"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.2459\/01.JCM.0000446386.01100.35"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2006.01512.x"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2004.01114.x"},{"key":"B31","unstructured":"Martini FH, Nath JL, Bartholomew EF. Fundamentals of anatomy and physiology. 10th edn. Boston (MA): Pearson; 2015"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.2006.163.4.600"},{"issue":"1","key":"B33","first-page":"22","volume":"17","author":"Meyer JM.","year":"2018","journal-title":"Curr Psychiatr"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2007.058198"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1111\/acem.13013"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2008.02.022"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00177.2005"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2006.046565"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01175.2013"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.09.049"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003347"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv093"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.06.1084"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbiomolbio.2015.12.015"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.598722"},{"key":"B49","first-page":"1","author":"Saedon NI","year":"2018","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfh614"},{"key":"B51","unstructured":"Seller RH, Symons AB. Differential diagnosis of common complaints. 6th edn. Philadelphia (PA): Elsevier Saunders; 2012"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-55136-6.00015-0"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012407"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2012.11.005"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2012.06.028"},{"key":"B57","unstructured":"Tortora GJ, Derrickson B. Principles of anatomy and physiology. Volume 2: maintenance and continuity of the human body. 13th edn. Hoboken (NJ): Wiley; 2011"},{"issue":"1","key":"B58","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/j.1540-8167.2007.00984.x","volume":"19","author":"Van Dijk N","year":"2008","journal-title":"Journal of Cardiovascular Electrophysiology"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2008.01946.x"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2018.08.012"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1497.2006.00450.x"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1111\/joim.12249"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2017.06.022"}],"container-title":["British Journal of Nursing"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/bjon.2020.29.9.506","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T21:05:32Z","timestamp":1722891932000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/bjon.2020.29.9.506"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,14]]},"references-count":55,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2020,5,14]]}},"alternative-id":["10.12968\/bjon.2020.29.9.506"],"URL":"https:\/\/doi.org\/10.12968\/bjon.2020.29.9.506","relation":{},"ISSN":["0966-0461","2052-2819"],"issn-type":[{"value":"0966-0461","type":"print"},{"value":"2052-2819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,14]]}}}