{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:54:14Z","timestamp":1790729654333,"version":"4.1.0"},"reference-count":9,"publisher":"Mark Allen Group","issue":"19","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Nurs"],"published-print":{"date-parts":[[2022,10,27]]},"abstract":"<jats:sec><jats:title>HIGHLIGHTS<\/jats:title><jats:p> Compare effectiveness of chemical disinfectants in reducing S. aureus. Five disinfectants reduced the bacterial load, especially chlorhexidine solutions. Focus on Brazilian clinical practice of needleless connector disinfection <\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose:<\/jats:title><jats:p> This study aimed to gain further knowledge about the comparative effectiveness of chemical disinfectants in reducing the bacterial load of NCs inoculated with S. aureus. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> Disinfection of needleless connectors was undertaken in vitro against S. aureus comparing 70% isopropyl alcohol (IPA), 70% ethanol, 0.5% and 2% chlorhexidine in 70% IPA applied with gauze, and 70% IPA single-use cap (Site-Scrub\u00ae). <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> All disinfectants reduced the bacterial load (P&lt;0.001), especially the chlorhexidine solutions. Mechanical friction should follow guidelines. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> This study found that all tested disinfectants effectively reduced the bacterial load and more clinical studies must be developed with a focus on the Brazilian clinical practice of needleless connector disinfection. <\/jats:p><\/jats:sec>","DOI":"10.12968\/bjon.2022.31.19.s26","type":"journal-article","created":{"date-parts":[[2022,10,28]],"date-time":"2022-10-28T16:47:37Z","timestamp":1666975657000},"page":"S26-S31","source":"Crossref","is-referenced-by-count":5,"title":["Disinfection of needleless connectors to reduce <i>Staphylococcus aureus<\/i> bacterial load"],"prefix":"10.12968","volume":"31","author":[{"given":"Patr\u00edcia Kuerten","family":"Rocha","sequence":"first","affiliation":[{"name":"Universidade Federal de Santa Catarina, Nursing Department, Paediatric Area, Gepesca Laboratory, Florian\u00f3polis, Brazil; Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico (CNPq), Brazil; Alliance for Vascular Access Teaching and Research, School of Nursing and Midwifery, Griffith University, Brisbane, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire M.","family":"Rickard","sequence":"additional","affiliation":[{"name":"Alliance for Vascular Access Teaching and Research, School of Nursing and Midwifery, Griffith University, Brisbane, Australia; School of Nursing, Midwifery and Social Work, The University of Queensland, Brisbane, Australia; Nursing and Midwifery Research Centre, Herston Infectious Diseases Institute, Metro North Health, Brisbane, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Cristina","family":"Gales","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo, Paulista School of Medicine, Internal Medicine Department, Division of Infectious Diseases, Alert Laboratory, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tha\u00eds Cristine Marques","family":"Sincero","sequence":"additional","affiliation":[{"name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico (CNPq), Brazil; Universidade Federal de Santa Catarina, Health Sciences Centre, Clinical Analysis Department, Molecular Microbiology Laboratory, Florian\u00f3polis, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gillian","family":"Ray-Barruel","sequence":"additional","affiliation":[{"name":"Alliance for Vascular Access Teaching and Research, School of Nursing and Midwifery, Griffith University, Brisbane, Australia; QEII Jubilee Hospital, Brisbane, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda J.","family":"Ullman","sequence":"additional","affiliation":[{"name":"Alliance for Vascular Access Teaching and Research, School of Nursing and Midwifery, Griffith University, Brisbane, Australia; School of Nursing, Midwifery and Social Work, The University of Queensland, Brisbane, Australia; Queensland Children's Hospital, Brisbane, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila Biazus","family":"Dalcin","sequence":"additional","affiliation":[{"name":"Universidade Federal de Santa Catarina, Nursing Department, Paediatric Area, Gepesca Laboratory, Florian\u00f3polis, Brazil; Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior (CAPES), Bras\u00edlia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mavilde L. Gon\u00e7alves","family":"Pedreira","sequence":"additional","affiliation":[{"name":"National Council for Scientific and Technological Development (CNPq), Brazil; Alliance for Vascular Access Teaching and Research, School of Nursing and Midwifery, Griffith University, Brisbane, Australia; Universidade Federal de S\u00e3o Paulo, Paediatric Nursing Department, LEEnf Laboratory, SEGTEC Research Group, Sao Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5130","reference":[{"key":"p_14","volume-title":"Midwifery and Social Work","author":"School"},{"key":"p_37","volume-title":"Methods for microbial needleless connector decontamination: a systematic review and meta-analysis.Am J Infect Control. 2019;47(8):956-962. https:\/\/pubmed. ncbi.nlm.nih.gov\/30824388\/.Accessed","author":"Flynn JM","year":"2021"},{"issue":"6","key":"p_38","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1177\/1129729820904904","volume":"21","author":"Rosenthal VD","year":"2020","journal-title":"J Vasc Access."},{"key":"p_39","first-page":"S1","volume":"39","author":"Gorski L","year":"2016","journal-title":"J Infus Nurs."},{"key":"p_40","first-page":"1","author":"O'Grady N","year":"2011","journal-title":"Centers for Disease Control."},{"issue":"1","key":"p_43","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1093\/jac\/dkx350","volume":"73","author":"Seas C","year":"2018","journal-title":"J Antimicrob Chemother."},{"issue":"9","key":"p_44","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/j.ajic.2019.11.030","volume":"48","author":"Slater K","year":"2020","journal-title":"Am J Infect Control."},{"issue":"5","key":"p_45","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1017\/ice.2016.330","volume":"38","author":"Flynn JM","year":"2017","journal-title":"Infect Control Hosp Epidemiol."},{"key":"p_46","volume-title":"https:\/\/pubmed.ncbi.nlm.nih.gov\/29632665\/. Accessed","author":"Casey AL","year":"2021"}],"container-title":["British Journal of Nursing"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/bjon.2022.31.19.S26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,28]],"date-time":"2022-10-28T16:51:27Z","timestamp":1666975887000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/bjon.2022.31.19.S26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,27]]},"references-count":9,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2022,10,27]]}},"alternative-id":["10.12968\/bjon.2022.31.19.S26"],"URL":"https:\/\/doi.org\/10.12968\/bjon.2022.31.19.s26","relation":{},"ISSN":["0966-0461","2052-2819"],"issn-type":[{"value":"0966-0461","type":"print"},{"value":"2052-2819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,27]]}}}