{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T22:04:53Z","timestamp":1761948293396},"reference-count":14,"publisher":"Mark Allen Group","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dent Update"],"published-print":{"date-parts":[[2012,1,2]]},"abstract":"<jats:p> Warfarin is an oral anticoagulant, used routinely for patients with atrial fibrillation, deep vein thrombosis, pulmonary embolism and those with a mechanical prosthetic valve. There are several noted adverse reactions associated with its use, in particular the risk of haemorrhage. Other adverse reactions include: hypersensitivity, rash, alopecia, diarrhoea, unexplained drop in haematocrit, purple toes, skin necrosis, jaundice, hepatic dysfunction, nausea, vomiting and pancreatitis. In this case report, an interesting potential adverse reaction to warfarin is discussed. The reaction described affected the patient's tongue, without affecting any other aspect of the oral cavity or body. <\/jats:p><jats:p> Clinical Relevance: This case report highlights the potential problems that can be encountered by patients on warfarin therapy, specifically, the possibility for hypersensitivity type reactions. <\/jats:p>","DOI":"10.12968\/denu.2012.39.1.33","type":"journal-article","created":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T10:20:20Z","timestamp":1501582820000},"page":"33-37","source":"Crossref","is-referenced-by-count":3,"title":["An interesting potential reaction to warfarin"],"prefix":"10.12968","volume":"39","author":[{"given":"Grainne Mc","family":"Avinchey","sequence":"first","affiliation":[{"name":"Senior House Officer, Department of Maxillofacial Surgery, Altnagelvin Area Hospital, Glenshane Road, Londonderry BT47 6SB, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Swinson","sequence":"additional","affiliation":[{"name":"Consultant, Department of Maxillofacial Surgery, Altnagelvin Area Hospital, Glenshane Road, Londonderry BT47 6SB, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5130","reference":[{"key":"B1","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/j.1365-2141.2005.05856.x","volume":"132","author":"Baglin TP","year":"2006","journal-title":"Br J Haematol"},{"issue":"6","key":"B2","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.7326\/0003-4819-68-6-1365","volume":"68","author":"Koch-Weser J.","year":"1968","journal-title":"Ann Internat Med"},{"key":"B3","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1056\/NEJM199106273242606","volume":"324","author":"Hirsh J.","year":"1991","journal-title":"New Engl J Med"},{"issue":"2","key":"B4","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0733-8635(05)70360-0","volume":"14","author":"Parks ET.","year":"1996","journal-title":"Dermatol Clin"},{"issue":"5","key":"B5","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S0738-081X(00)00143-7","volume":"18","author":"Porter SR","year":"2000","journal-title":"Clin Dermatol"},{"issue":"4","key":"B6","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1177\/154411130401500405","volume":"15","author":"Scully C","year":"2004","journal-title":"Crit Rev Oral Biol Med"},{"issue":"3","key":"B7","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0011-8532(22)02230-3","volume":"28","author":"Wright JM.","year":"1984","journal-title":"Dent Clin N Am"},{"issue":"3","key":"B8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5005\/jcdp-9-3-1","volume":"9","author":"Abdollahi M","year":"2008","journal-title":"J Contemp Dental Pract"},{"key":"B9","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1592\/phco.23.4.533.32130","volume":"23","author":"Spyropoulos AC.","year":"2003","journal-title":"Pharmacotherapy"},{"issue":"5","key":"B10","first-page":"78","volume":"113","author":"Martin CM","year":"1970","journal-title":"Calif Med"},{"issue":"7","key":"B11","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1001\/archderm.1984.01650430113021","volume":"120","author":"Franson TR","year":"1984","journal-title":"Archiv Dermat"},{"issue":"1","key":"B12","volume":"9","author":"Shariat-Moharreri R","year":"2005","journal-title":"Internet J Anaesthesiol"},{"key":"B13","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/0002-9149(59)90403-5","volume":"3","author":"Sheps SG","year":"1959","journal-title":"Am J Cardiol"},{"key":"B14","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1161\/01.CIR.22.5.947","volume":"22","author":"Adams CW","year":"1960","journal-title":"Circulation"}],"container-title":["Dental Update"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/denu.2012.39.1.33","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T18:12:13Z","timestamp":1653415933000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/denu.2012.39.1.33"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1,2]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1,2]]}},"alternative-id":["10.12968\/denu.2012.39.1.33"],"URL":"https:\/\/doi.org\/10.12968\/denu.2012.39.1.33","relation":{},"ISSN":["0305-5000","2515-589X"],"issn-type":[{"value":"0305-5000","type":"print"},{"value":"2515-589X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,2]]}}}