{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T20:19:13Z","timestamp":1770409153553,"version":"3.49.0"},"reference-count":32,"publisher":"IMR Press","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Hosp Med"],"published-print":{"date-parts":[[2017,3,2]]},"abstract":"<jats:p>An understanding of how to counteract the anticoagulant effect of direct oral anticoagulants is essential in the event of haemorrhage, emergency surgery and overdose. This review summarizes strategies for the reversal of direct oral anticoagulants, including the use of novel agents.<\/jats:p>","DOI":"10.12968\/hmed.2017.78.3.165","type":"journal-article","created":{"date-parts":[[2017,3,9]],"date-time":"2017-03-09T12:28:01Z","timestamp":1489062481000},"page":"165-169","source":"Crossref","is-referenced-by-count":1,"title":["Reversal of direct oral anticoagulants"],"prefix":"10.31083","volume":"78","author":[{"given":"X-Y","family":"Zhang","sequence":"first","affiliation":[{"name":"Haematology Specialist Registrar, Department of Haematology, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MJ","family":"Desborough","sequence":"additional","affiliation":[{"name":"Clinical Research Fellow, NHS Blood and Transplant, John Radcliffe Hospital, Oxford, and Oxford Clinical Research in Transfusion Medicine, Nuffield Division of Clinical Laboratory Sciences, University of Oxford, Oxford"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Shapiro","sequence":"additional","affiliation":[{"name":"Consultant Haematologist, Oxford Haemophilia and Thrombosis Centre, Oxford Comprehensive Biomedical Resource Centre, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford OX3 7LE"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16242","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.h1857"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1411800"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2016.07.008"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-014-0261-1"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-07-590323"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.h1585"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0905561"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1607887"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.13810"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1160\/TH13-05-0431"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)60732-2"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1310907"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.02.549"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.14344"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1160\/TH12-08-0573"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1111\/jth.13227"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.002332"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12107"},{"key":"B20","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1160\/TH07-12-0714","volume":"100","author":"Mueck W","year":"2008","journal-title":"Thromb Haemost"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1606424"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1009638"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1080\/15563650.2016.1240805"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu083"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1502000"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)62343-0"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61943-7"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60835-5"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.14371"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1510991"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2015.11.024"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1160\/TH09-11-0758"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000002310"}],"container-title":["British Journal of Hospital Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/hmed.2017.78.3.165","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T10:04:57Z","timestamp":1770372297000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/BJHM\/78\/3\/10.12968\/hmed.2017.78.3.165"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,2]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3,2]]}},"alternative-id":["10.12968\/hmed.2017.78.3.165"],"URL":"https:\/\/doi.org\/10.12968\/hmed.2017.78.3.165","relation":{},"ISSN":["1750-8460","1759-7390"],"issn-type":[{"value":"1750-8460","type":"print"},{"value":"1759-7390","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,2]]}}}