{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:52:44Z","timestamp":1791978764831,"version":"4.4.0"},"reference-count":25,"publisher":"IMR Press","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Hosp Med"],"published-print":{"date-parts":[[2019,4,2]]},"abstract":"<jats:p>This literature review clarifies the role of radiotherapy in the management of low-volume haemoptysis. Embase and Medline were interrogated, and PRISMA guidelines were then used to select relevant articles. Seventy-eight articles were considered relevant and manually reviewed.<\/jats:p>\n                  <jats:p>The evidence suggests that external beam radiotherapy is more effective than endobronchial brachytherapy at controlling low-volume haemoptysis. There is no evidence to recommend a combination of the two techniques. Different doses and fractionations appear equally effective, with a potential survival advantage of higher dose regimens for fitter patients.<\/jats:p>\n                  <jats:p>Palliative radiotherapy is effective at controlling low-volume haemoptysis. External beam radiotherapy is the first-line treatment, with endobronchial brachytherapy recommended following external beam radiotherapy failure. Choice of dose and fractionation should take into account the patient's performance status.<\/jats:p>","DOI":"10.12968\/hmed.2019.80.4.211","type":"journal-article","created":{"date-parts":[[2019,4,5]],"date-time":"2019-04-05T13:06:11Z","timestamp":1554469571000},"page":"211-215","source":"Crossref","is-referenced-by-count":5,"title":["Radiotherapy in the control of bleeding from primary and secondary lung tumours"],"prefix":"10.31083","volume":"80","author":[{"given":"Simona","family":"Gaito","sequence":"first","affiliation":[{"name":"Clinical Research fellow, Department of Radiotherapy, The Christie NHS Foundation Trust, Manchester M20 4BX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Hughes","sequence":"additional","affiliation":[{"name":"ST5 (registrar), Department of Radiotherapy, The Christie NHS Foundation Trust, Manchester"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Woolf","sequence":"additional","affiliation":[{"name":"Clinical Oncology Consultant, Department of Radiotherapy, The Christie NHS Foundation Trust, Manchester"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganesh","family":"Radhakrishna","sequence":"additional","affiliation":[{"name":"Clinical Oncology Consultant, Department of Radiotherapy, The Christie NHS Foundation Trust, Manchester"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16242","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-5002(01)00249-5"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1991.62"},{"issue":"6","key":"B3","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1038\/bjc.1992.196","volume":"65","author":"Anonymous","year":"1992","journal-title":"Br J Cancer"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19851015)56:8<2107::AID-CNCR2820560837>3.0.CO;2-T"},{"key":"B5","first-page":"1567","volume":"2","author":"Dobbertin I","year":"1999","journal-title":"Anticancer Res"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.brachy.2017.01.003"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2004.09.008"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.15.3312"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199001000-00001"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1378\/chest.112.2.440"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2013.54.2.403"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1186\/s13014-016-0608-8"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/S0936-6555(96)80041-0"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(00)00607-6"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2008.03.018"},{"issue":"11","key":"B16","first-page":"CD008711","volume":"11","author":"Prutsky G","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/S0936-6555(05)80446-7"},{"issue":"12","key":"B18","first-page":"CD004284","volume":"12","author":"Reveiz L","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1016\/j.prro.2011.01.005"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6602477"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(85)90307-4"},{"key":"B23","first-page":"CD002143","volume":"1","author":"Stevens R","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/j.brachy.2015.09.006"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.06.123"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.3816\/CLC.2010.n.023"}],"container-title":["British Journal of Hospital Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/hmed.2019.80.4.211","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T10:03:27Z","timestamp":1770372207000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/BJHM\/80\/4\/10.12968\/hmed.2019.80.4.211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,2]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,4,2]]}},"alternative-id":["10.12968\/hmed.2019.80.4.211"],"URL":"https:\/\/doi.org\/10.12968\/hmed.2019.80.4.211","relation":{},"ISSN":["1750-8460","1759-7390"],"issn-type":[{"value":"1750-8460","type":"print"},{"value":"1759-7390","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,2]]}}}