{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T19:24:47Z","timestamp":1793215487845,"version":"4.5.0"},"reference-count":25,"publisher":"IMR Press","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Hosp Med"],"published-print":{"date-parts":[[2020,5,2]]},"abstract":"<jats:p>Community-acquired pneumonia is a common clinical problem requiring admission to hospital, with a particularly high incidence in the elderly population and those with significant comorbidities. Diagnosis is made on the combination of a short history of respiratory symptoms and systemic ill-health with new examination and\/or radiological features of consolidation. Multiple other infective and non-infective conditions can mimic community-acquired pneumonia, leading to misdiagnosis in 5\u201317% of cases. The CURB-65 score can identify patients with community-acquired pneumonia with a higher risk of mortality, but is insensitive at identifying patients requiring intensive care support and needs to be combined with clinical markers of potential severity. Both high admission levels of C-reactive protein and the failure of levels of C-reactive protein to decline by &gt;50% by day 4 after admission are associated with higher risk of complications, need for ventilation or inotropic support, and mortality. Empirical antibiotic therapy for most patients admitted to hospital is combination of a \u00df-lactam and a macrolide. Short courses of antibiotics do not result in significantly different outcomes to longer courses unless the patient has developed complications such as a complex parapneumonic effusion. Implementation of a community-acquired pneumonia care bundle into clinical practice reduces mortality, and should be a high priority for all acute hospitals.<\/jats:p>","DOI":"10.12968\/hmed.2020.0124","type":"journal-article","created":{"date-parts":[[2020,5,23]],"date-time":"2020-05-23T09:11:55Z","timestamp":1590225115000},"page":"1-9","source":"Crossref","is-referenced-by-count":2,"title":["Management of community-acquired pneumonia: essential tips for the physician on call"],"prefix":"10.31083","volume":"81","author":[{"given":"Malcolm","family":"Avari","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, University College London Hospitals Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy S","family":"Brown","sequence":"additional","affiliation":[{"name":"UCL Respiratory, Department of Medicine, University College London, Rayne Institute, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16242","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1093\/ajhp\/zxz068"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1186\/s41479-016-0002-1"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1086\/589754"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2007.10.033"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2008.105080"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1186\/s41479-017-0039-9"},{"issue":"2","key":"B7","first-page":"35","volume":"6","author":"Cill\u00f3niz C","year":"2018","journal-title":"Med Sci"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy723"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0191721"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2018.06.017"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9010275"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18020388"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2007.04.023"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2009.121434"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2015-206834"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1038\/srep22911"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201512-848OC"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1186\/s12931-018-0781-4"},{"issue":"5","key":"B19","first-page":"167","volume":"16","author":"Morgan AJ","year":"2016","journal-title":"Br J Anaesth Educ"},{"key":"B20","unstructured":"National Institute for Health and Care Excellence. Pneumonia (community-acquired): antimicrobial prescribing (NG138). 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