{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T20:51:07Z","timestamp":1790887867300,"version":"4.1.0"},"reference-count":45,"publisher":"IMR Press","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Hosp Med"],"published-print":{"date-parts":[[2024,4,2]]},"abstract":"<jats:p>There is a significant burden of cardiovascular disease morbidity and mortality in the end-stage kidney disease population, driven by traditional and non-traditional risk factors. Despite its prevalence, heart failure is difficult to diagnose in the dialysis population due to overlapping clinical presentations, limitations of investigations, and the impact on the cardiorenal axis. \u2018Foundation therapies\u2019 are the key medications which improve patient outcomes in heart failure with reduced ejection fraction and include beta-blockers, renin-angiotensin-aldosterone system inhibitors and sodium-glucose cotransporter-2 inhibitors. They are underutilised in the dialysis population due to the exclusion of chronic kidney disease patients from major trials and legitimate clinical concerns e.g. hyperkalaemia, intradialytic hypotension and residual kidney function preservation. A coordinated cardiorenal multidisciplinary approach can guide appropriate diagnostic considerations (biomarkers interpretation, imaging, addressing unique complications of kidney disease), optimise dialysis management (prescription length, frequency and ultrafiltration targets) and when at euvolaemia facilitate the stepwise introduction of appropriate foundation therapies.<\/jats:p>","DOI":"10.12968\/hmed.2023.0452","type":"journal-article","created":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T10:45:20Z","timestamp":1715597120000},"page":"1-10","source":"Crossref","is-referenced-by-count":3,"title":["What to do with foundation therapies for heart failure for patients with end-stage kidney disease on haemodialysis"],"prefix":"10.31083","volume":"85","author":[{"given":"Sherna F","family":"Adenwalla","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Sciences, University of Leicester, Leicester, UK"},{"name":"Department of Renal Medicine, University 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