{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T17:20:16Z","timestamp":1770744016393,"version":"3.49.0"},"reference-count":33,"publisher":"IMR Press","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hospital Medicine"],"published-print":{"date-parts":[[2002,11]]},"abstract":"<jats:p>A proportion of children and adults with moderate to severe atopic eczema are not adequately controlled with emollients and topical steroids, resulting in significant morbidity and disability. Studies indicate a significant placebo response, so randomized controlled trials of new treatments are vital. This article reviews the evidence for phototherapy and systemic treatments in atopic eczema.<\/jats:p>","DOI":"10.12968\/hosp.2002.63.11.1910","type":"journal-article","created":{"date-parts":[[2014,5,23]],"date-time":"2014-05-23T11:31:25Z","timestamp":1400844685000},"page":"657-661","source":"Crossref","is-referenced-by-count":0,"title":["Phototherapy and systemic treatments"],"prefix":"10.31083","volume":"63","author":[{"given":"Nick J","family":"Reynolds","sequence":"first","affiliation":[{"name":"Department of Dermatology, Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne NE2 4HH and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon J","family":"Meggitt","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne NE2 4HH"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16242","reference":[{"key":"p_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2002.01709.x"},{"key":"p_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(96)90281-9"},{"key":"p_3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1994.tb02910.x"},{"key":"p_4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1997.tb03733.x"},{"key":"p_5","doi-asserted-by":"publisher","DOI":"10.1038\/75977"},{"key":"p_6","doi-asserted-by":"publisher","DOI":"10.1038\/86867"},{"key":"p_7","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1998.02316.x"},{"key":"p_8","first-page":"342","volume":"147","author":"Graham-Brown RA","year":"2002","journal-title":"Br J Dermatol"},{"key":"p_9","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(93)70026-P"},{"key":"p_10","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.308.6927.489"},{"key":"p_11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1996.tb03600.x"},{"key":"p_12","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199712113372403"},{"key":"p_13","doi-asserted-by":"publisher","DOI":"10.3310\/hta4370"},{"key":"p_14","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2000.104793"},{"key":"p_15","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(98)70123-9"},{"key":"p_16","doi-asserted-by":"publisher","DOI":"10.1038\/82625"},{"key":"p_17","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(90)90079-J"},{"key":"p_18","doi-asserted-by":"publisher","DOI":"10.1038\/ng1096-231"},{"key":"p_19","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2230.2001.00837.x"},{"key":"p_20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1978.tb07329.x"},{"key":"p_21","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.04922.x"},{"key":"p_22","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2000.03667.x"},{"key":"p_23","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1998.02122.x"},{"issue":"3","key":"p_24","first-page":"241","volume":"31","author":"Reynolds NJ","year":"1997","journal-title":"J R Coll Physicians Lond"},{"key":"p_25","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)05114-X"},{"key":"p_26","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)62968-7"},{"key":"p_27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1993.tb03171.x"},{"key":"p_28","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)92424-E"},{"key":"p_29","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)90134-B"},{"key":"p_30","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(94)70068-0"},{"key":"p_31","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1997.tb14942.x"},{"key":"p_32","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(93)70067-4"},{"key":"p_33","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)92617-8"}],"container-title":["Hospital Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/hosp.2002.63.11.1910","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T01:42:04Z","timestamp":1770687724000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/BJHM\/63\/11\/10.12968\/hosp.2002.63.11.1910"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,11]]},"references-count":33,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2002,11]]}},"alternative-id":["10.12968\/hosp.2002.63.11.1910"],"URL":"https:\/\/doi.org\/10.12968\/hosp.2002.63.11.1910","relation":{},"ISSN":["1462-3935","2053-4299"],"issn-type":[{"value":"1462-3935","type":"print"},{"value":"2053-4299","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,11]]}}}