{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T13:31:00Z","timestamp":1764250260575},"reference-count":38,"publisher":"Mark Allen Group","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Palliat Nurs"],"published-print":{"date-parts":[[2023,3,2]]},"abstract":"<jats:sec><jats:title>Background:<\/jats:title><jats:p> Patients with metastatic non-small cell lung cancer (NSCLC) often experience severe eating disorders and other problems because of rapid disease progression and various therapies, which significantly affect their quality of life (QoL). <\/jats:p><\/jats:sec><jats:sec><jats:title>Aims:<\/jats:title><jats:p> This study aimed to assess the nutritional status and QoL of patients with NSCLC at the start of immunotherapy and 3 months later. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> This study used a prospective, observational, consecutive sampling approach and was carried out between July 2018 and August 2019. The convenience sample comprised 60 patients treated in the oncology ward and the day care department of a public hospital in Greece. Their nutritional status was assessed using the Mini Nutritional Assessment questionnaire and their QoL using the European Organization for Research and Treatment of Cancer QLQ-C30 questionnaire and its QLQ-LC13 module. They were evaluated at the start of immunotherapy (phase I) and 3 months later (phase II). <\/jats:p><\/jats:sec><jats:sec><jats:title>Findings:<\/jats:title><jats:p> Of the initial 60 patients, 25% had died and 23.3% declined to participate by phase II. Of the 31 patients (51.7%) who completed the study, 64.5% had been assessed as malnourished at phase I; at phase II, this had decreased to 32.3%, so nutritional status appeared to have significantly improved. There were also significant improvements between phases I and II in global health status\/QoL, as well as in the physical, roles, emotional and social dimensions. Additionally, all nine symptoms of QLQ-C30 significantly decreased, while the QLQ-LC13 showed significant improvements in dyspnoea, alopecia and pain in parts of the body other than the chest, arm or shoulder. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> Metastatic NSCLC patients' QoL and nutritional status significantly improved after 3 months' immunotherapy. <\/jats:p><\/jats:sec>","DOI":"10.12968\/ijpn.2023.29.3.118","type":"journal-article","created":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T17:37:26Z","timestamp":1679593046000},"page":"118-128","source":"Crossref","is-referenced-by-count":4,"title":["Nutritional assessment and quality of life in patients with non-small cell lung cancer undergoing immunotherapy"],"prefix":"10.12968","volume":"29","author":[{"given":"Theocharis","family":"Konstantinidis","sequence":"first","affiliation":[{"name":"Assistant Professor, Department of Nursing, Hellenic Mediterranean University, Heraklion, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chrysi","family":"Fragkioudaki","sequence":"additional","affiliation":[{"name":"Registered Nurse, Medical Oncology Department, University General Hospital of Heraklion, Heraklion, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evridiki","family":"Patelarou","sequence":"additional","affiliation":[{"name":"Professor, Department of Nursing, Hellenic Mediterranean University, Heraklion, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michail","family":"Zografakis-Sfakianakis","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Nursing, Hellenic Mediterranean University, Heraklion, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Symeon","family":"Naoum","sequence":"additional","affiliation":[{"name":"Doctor of Medicine, Resident of Orthopaedic Surgery Orthopaedic Department, 251 Air Force General Hospital, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioanna","family":"Tsatsou","sequence":"additional","affiliation":[{"name":"Registered Nurse, Oncology-Haematology Department, 251 Air Force General Hospital, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioannis","family":"Kalemikerakis","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Nursing, University of West Attica, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ourania","family":"Govina","sequence":"additional","affiliation":[{"name":"Professor, Department of Nursing, University of West Attica, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5130","reference":[{"issue":"5","key":"B1","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1093\/jnci\/85.5.365","volume":"3","author":"Aaronson NK","year":"1993","journal-title":"J Natl Cancer Inst"},{"issue":"11","key":"B2","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1038\/nrc3829","volume":"14","author":"Argil\u00e9s JM","year":"2014","journal-title":"Nat Rev Cancer"},{"issue":"5","key":"B3","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/0959-8049(94)90535-5","volume":"30","author":"Bergman B","year":"1994","journal-title":"Eur J Cancer"},{"issue":"1","key":"B4","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1186\/1471-2407-11-353","volume":"11","author":"Braun DP","year":"2011","journal-title":"BMC Cancer"},{"key":"B5","unstructured":"Fayers P, Aaronson NK, Bjordal K et al. 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