{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,26]],"date-time":"2024-05-26T23:40:01Z","timestamp":1716766801932},"reference-count":28,"publisher":"Mark Allen Group","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2003,4]]},"abstract":"<jats:p>Toxic epidermal necrolysis, a life-threatening reaction to certain types of drugs, is characterised by epidermal sloughing of more than 30% of the total body surface area. Patient survival depends on prompt referral to a specialist burns unit.<\/jats:p>","DOI":"10.12968\/jowc.2003.12.4.26485","type":"journal-article","created":{"date-parts":[[2014,5,23]],"date-time":"2014-05-23T15:58:12Z","timestamp":1400860692000},"page":"151-154","source":"Crossref","is-referenced-by-count":4,"title":["Management of toxic epidermal necrolysis in a 15-year-old girl"],"prefix":"10.12968","volume":"12","author":[{"given":"S.","family":"Clennett","sequence":"first","affiliation":[{"name":"Burns and Surgical Specialities Unit, Royal Hobart Hospital, Hobart, Tasmania, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Hosking","sequence":"additional","affiliation":[{"name":"Smith and Nephew, Mount Waverley, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5130","reference":[{"key":"p_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004630-200021030-00004"},{"key":"p_3","first-page":"999","volume":"40","author":"Stevens-Johnson","year":"2000","journal-title":"J Assoc Physicians of India"},{"key":"p_5","doi-asserted-by":"publisher","DOI":"10.1016\/S0305-4179(98)00191-0"},{"key":"p_6","doi-asserted-by":"publisher","DOI":"10.1097\/00004630-200203000-00004"},{"key":"p_7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199512143332404"},{"key":"p_9","doi-asserted-by":"publisher","DOI":"10.1097\/00004630-199920060-00012"},{"key":"p_10","volume-title":"Mims.Annual Australian 2001","edition":"25"},{"key":"p_20","unstructured":"Daily silver sulphadiazine cream dressings were used for the first six days, after which the nursing staff advocated that they be replaced by an antibacterial sheet dressing, Acticoat (Smith and Nephew). Acticoat is a nanocrystalline silver-coated sheet dressing activated by sterile water to produce a rapid, long-lasting kill of a broad spectrum of bacteria.8,9A major benefit is its extended duration of activity, which meant the dressing could be left intact for a minimum of three days. A `burn dressing' (large sheets of cotton gauze folded several times to create an absorbent pad) was used as a secondary dressing. Conforming bandages and cotton stockinettes were used to create a vest, sleeves, leggings and pants (Figs 5 and 6). This garment remained intact for five days."},{"key":"p_27","unstructured":"Lyell10used the term toxic epidermal necrolysis in 1956 to describe the clinical presentation of four cases of a disease similar to scalding. The large areas of blisters and epidermal skin loss were clinically Fig 5 and 6. 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