{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:44:44Z","timestamp":1759333484456},"reference-count":16,"publisher":"Mark Allen Group","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2004,11]]},"abstract":"<jats:p> Werner\u2019s syndrome is a rare premature ageing syndrome caused by mutations in the WRN gene. The disease spectrum shows sclero edematous skin changes, with chronic ulcerations, cutaneous wound-healing impairment and calcification. Juvenile cataract, arteriosclerosis, a higher risk of malignancy and diabetes mellitus are also often found. <\/jats:p>","DOI":"10.12968\/jowc.2004.13.10.26690","type":"journal-article","created":{"date-parts":[[2017,12,24]],"date-time":"2017-12-24T04:39:33Z","timestamp":1514090373000},"page":"415-416","source":"Crossref","is-referenced-by-count":11,"title":["Topical PDGF-BB results in limited healing in a patient with Werner\u2019s syndrome and chronic leg ulcers"],"prefix":"10.12968","volume":"13","author":[{"given":"U.","family":"Wollina","sequence":"first","affiliation":[{"name":"Dermatology and Venerology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Gruner","sequence":"additional","affiliation":[{"name":"Department of Dermatology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Koch","sequence":"additional","affiliation":[{"name":"Department of Dermatology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"K&#246;stler","sequence":"additional","affiliation":[{"name":"Department of Dermatology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Hubl","sequence":"additional","affiliation":[{"name":"The Institute of Clinical Chemistry and Laboratory Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.B.","family":"Hanson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Oshima","sequence":"additional","affiliation":[{"name":"1 Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5130","reference":[{"key":"p_1","doi-asserted-by":"publisher","DOI":"10.1177\/1534734604265142"},{"key":"p_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19981215)83:12B+<2833::AID-CNCR35>3.0.CO;2-3"},{"key":"p_3","doi-asserted-by":"publisher","DOI":"10.1159\/000056841"},{"key":"p_16","volume-title":"Biocentre","author":"Schindler"},{"key":"p_18","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.11.8.3905"},{"key":"p_20","doi-asserted-by":"publisher","DOI":"10.1126\/science.3022382"},{"key":"p_21","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1985.01660050088021"},{"key":"p_23","doi-asserted-by":"publisher","DOI":"10.1159\/000052777"},{"key":"p_24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1982.tb00283.x"},{"key":"p_25","first-page":"721","volume":"42","author":"H\u00fcrlimann F.","year":"1991","journal-title":"Hautarzt"},{"key":"p_26","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-199510000-00017"},{"key":"p_27","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.240450403"},{"key":"p_28","doi-asserted-by":"publisher","DOI":"10.1517\/14712598.2.2.211"},{"key":"p_29","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2001.00348.x"},{"key":"p_31","doi-asserted-by":"publisher","DOI":"10.1080\/000155501317140115"},{"key":"p_32","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.1993.tb00755.x"}],"container-title":["Journal of Wound Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/jowc.2004.13.10.26690","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T02:40:09Z","timestamp":1653360009000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/jowc.2004.13.10.26690"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,11]]},"references-count":16,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2004,11]]}},"alternative-id":["10.12968\/jowc.2004.13.10.26690"],"URL":"https:\/\/doi.org\/10.12968\/jowc.2004.13.10.26690","relation":{},"ISSN":["0969-0700","2052-2916"],"issn-type":[{"value":"0969-0700","type":"print"},{"value":"2052-2916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,11]]}}}