{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T17:54:13Z","timestamp":1697046853462},"reference-count":29,"publisher":"Mark Allen Group","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:p>Although the number of cases of calciphylaxis is increasing, it is often not diagnosed until a late stage, increasing the risk of mortality. A characteristic is purple, mottled and painful lesions, which have a tendency to become necrotic<\/jats:p>","DOI":"10.12968\/jowc.2005.14.1.26728","type":"journal-article","created":{"date-parts":[[2014,5,23]],"date-time":"2014-05-23T15:58:36Z","timestamp":1400860716000},"page":"12-13","source":"Crossref","is-referenced-by-count":3,"title":["Spotting the signs: a case of late diagnosed painful calciphylaxis"],"prefix":"10.12968","volume":"14","author":[{"given":"C.","family":"Payasli","sequence":"first","affiliation":[{"name":"Zonguldak Karaelmas University, Zonguldak, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Hosnuter","sequence":"additional","affiliation":[{"name":"Zonguldak Karaelmas University, Zonguldak, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Babuccu","sequence":"additional","affiliation":[{"name":"Zonguldak Karaelmas University, Zonguldak, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Kargi","sequence":"additional","affiliation":[{"name":"Zonguldak Karaelmas University, Zonguldak, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Kocak","sequence":"additional","affiliation":[{"name":"Zonguldak Karaelmas University, Zonguldak, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Isikdemir","sequence":"additional","affiliation":[{"name":"Zonguldak Karaelmas University, Zonguldak, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5130","reference":[{"key":"p_3","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2003.12018.x"},{"key":"p_5","doi-asserted-by":"publisher","DOI":"10.1081\/RRS-120014585"},{"key":"p_6","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197302000-00015"},{"key":"p_7","volume-title":"Department of Plastic and Reconstructive Surgery","author":"Payasli MD"},{"key":"p_8","volume-title":"Department of Plastic and Reconstructive Surgery","author":"Associated Professor"},{"key":"p_15","unstructured":"Calciphylaxis is one of a series of systemic calcification syndromes that are complications of secondary hyperparathyroidism in chronic renal failure.3-8However, it is rare and not seen in all patients with chronic renal failure unless secondary hyperparathyroidism occurs, in which case the risk of it developing increases significantly."},{"key":"p_16","volume-title":"the development of necrotic ulcers is almost inevitable. Chronic renal failure and hyperparathyroidism act as sensitising agents, resulting in a high calcium-phosphate product (Ca2+-P3-","author":"Once"},{"key":"p_20","volume-title":"in 196412 and then uraemic gangrene syndrome by Torok","author":"This","year":"1991"},{"key":"p_22","unstructured":"In most cases, necrotic lesions begin as painful, red to purple livedoid plaques.14,18-21Generally, the lower extremity involvement is symmetrical, although the trunk and upper extremities may also be affected.22In this case we were unable to ascertain when the necrosis began and only made a diagnosis after the lesions had developed."},{"key":"p_23","unstructured":"In 1981 there were only about 50 recorded cases of calciphylaxis in the literature, but as stated above the number of such cases is rising. Calciphylaxis presents a challenge to plastic and reconstructive surgeons and nephrologists. Treatment should be considered part of renal disease management, and might benefit from inclusion in plastic surgery textbooks. Above all, it is very painful and progressive condition, so practitioners need to be aware of its manifestations and management. \u25a0 Fig 1. The affected foot of the patient. Note the large wound surface with eschar tissue"},{"key":"p_24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1983.tb03996.x"},{"key":"p_27","doi-asserted-by":"crossref","unstructured":"parathyroidectomy. 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