{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T20:54:59Z","timestamp":1792702499329,"version":"4.5.0"},"reference-count":53,"publisher":"Mark Allen Group","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:p> Moderate trauma is the major cause of pelvic fractures in older people. The incidence is about 20\u201330 per 100,000, and the female-to-male ratio is about 3:1. Most fractures can be treated conservatively. This paper reports a rare complication of this fracture \u2014 necrotising fasciitis of the leg. The patient presented at our hospital with a simple closed pelvic fracture. The fracture caused a perforation of the small bowel and subsequent necrotising fasciitis of the left upper leg. A segment of small bowel was removed and the necrotising fasciitis was treated with repeated surgical debridement, broadspectrum antibiotic therapy, maggot debridement therapy (MDT) and topical negative pressure (TNP) therapy. The wound finally closed and the patient became mobile. The case is described and relevant literature is reviewed. <\/jats:p>","DOI":"10.12968\/jowc.2006.15.3.26875","type":"journal-article","created":{"date-parts":[[2014,5,23]],"date-time":"2014-05-23T15:59:04Z","timestamp":1400860744000},"page":"117-120","source":"Crossref","is-referenced-by-count":11,"title":["Necrotising fasciitis of the leg following a simple pelvic fracture: case report and literature review"],"prefix":"10.12968","volume":"15","author":[{"given":"A.L.","family":"Rozeboom","sequence":"first","affiliation":[{"name":"Department of Surgery, Leiden University medical Centre, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Steenvoorde","sequence":"additional","affiliation":[{"name":"Department of Surgery, Leiden University medical Centre, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.H.","family":"Hartgrink","sequence":"additional","affiliation":[{"name":"Department of Surgery"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.N","family":"Jukema","sequence":"additional","affiliation":[{"name":"Department of Traumatology, Leiden University medical Centre, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5130","reference":[{"key":"p_2","doi-asserted-by":"publisher","DOI":"10.3109\/17453679209154786"},{"key":"p_3","doi-asserted-by":"publisher","DOI":"10.3109\/17453679508995533"},{"key":"p_5","first-page":"27S","volume":"169","author":"Treatment","year":"1995","journal-title":"Am J Surg"},{"key":"p_7","first-page":"366","volume":"168","author":"Necrotising","year":"2002","journal-title":"Eur J Surg"},{"key":"p_8","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199611000-00011"},{"key":"p_10","volume-title":"Curr Opin Infect Dis 2005"},{"key":"p_11","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.330.7495.830"},{"key":"p_13","doi-asserted-by":"publisher","DOI":"10.1007\/BF02588060"},{"key":"p_14","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0022-5347(17)37162-8","volume":"147","author":"Perry M.O.","year":"1992","journal-title":"J Urol"},{"key":"p_16","volume-title":"Third conference of the European Wound","author":"Steenvoorde P."},{"key":"p_17","unstructured":"Management Association, Pisa (Italy), 22-24 May 2003; www.ewma.org\/ pisa2003\/pdf\/044."},{"key":"p_18","doi-asserted-by":"publisher","DOI":"10.1007\/s001130050318"},{"key":"p_19","series-title":"Fig 7","volume-title":"The wound healed fully","author":"Two"},{"key":"p_21","unstructured":"Necrotising fasciitis affects the subcutaneous fat, superficial fascia and superior surface of the deep fascia. The skin is initially intact but becomes gangrenous secondary to interruption of its deep blood supply.12The condition was described in 1871 by Jones13and in 1924 by Meleney, and was named in 1952. The first known report of it was by Hippocrates.14-16"},{"key":"p_24","volume-title":"TNP therapy and MDT were successfully used in this patient. Since the first published report of TNP","author":"Along","year":"1997"},{"key":"p_25","unstructured":"There are numerous indications for TNP including complicated surgical wounds, laparostomies and chronic wounds.21,25-27There is a low incidence of localised superficial skin irritation if the vacuum sponge overlaps the normal skin. In this case, therefore, the polyvinylalcohol foam (Versa Foam, KCI) was used as it causes less soft-tissue irritation.26"},{"key":"p_27","unstructured":"MDTdates back to the 1920s in the US35and is a valuable treatment option in modern surgery.36,37The maggots' extracorporeal digestive system releases enzymes such as tryptase, peptidase and lipase, which break down debris and necrotic tissue while leaving healthy tissue unharmed. The therapy can prevent amputation and preserve patients' quality of life.38It is particularly effective in the treatment of wounds infected with Gram-positive bacteria.39,40"},{"key":"p_33","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800620510"},{"key":"p_34","volume-title":"US Sanitary Commission. Surgical Memoirs of the War of Rebellion. 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