{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T08:44:35Z","timestamp":1782981875964,"version":"3.54.5"},"reference-count":23,"publisher":"Mark Allen Group","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2006,5]]},"abstract":"<jats:sec><jats:title>Objective:<\/jats:title><jats:p> To compare the effect of the sustained silver-releasing foam dressing Contreet Foam (Coloplast A\/S) with local best practice (LBP) on delayed healing ulcers using a real-life setting. <\/jats:p><\/jats:sec><jats:sec><jats:title>Method:<\/jats:title><jats:p> A total of 619 patients with ulcers of varying aetiologies were treated for four weeks with either the silver foam dressing or LBP. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> Wound area was reduced by 50% with the silver foam and 34% with LBP. Less slough and maceration, a faster reduction in exudate level and more positive wound progress was achieved with the silver foam. In addition, exudate handling, ease of use, odour and pain improved. Less time was spent on dressing changes, and mean wear time was longer for the silver foam (3.1 days) than for LBP (2.1 days). All differences were statistically significant (p&lt;0.05). The silver foam dressing outperformed all of the other dressing categories including moist wound healing products and other silver dressings. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> This large-scale comparative real-life study shows that the silver foam dressing supports faster healing of delayed healing wounds. <\/jats:p><\/jats:sec><jats:sec><jats:title>Declaration of interest:<\/jats:title><jats:p> The study was financially supported by Coloplast A\/S, Humlebaek, Denmark. <\/jats:p><\/jats:sec>","DOI":"10.12968\/jowc.2006.15.5.26909","type":"journal-article","created":{"date-parts":[[2014,5,23]],"date-time":"2014-05-23T15:59:18Z","timestamp":1400860758000},"page":"199-206","source":"Crossref","is-referenced-by-count":94,"title":["Effect of a sustained silver-releasing dressing on ulcers with delayed healing: the CONTOP study"],"prefix":"10.12968","volume":"15","author":[{"given":"K.-C.","family":"Munter","sequence":"first","affiliation":[{"name":"Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Beele","sequence":"additional","affiliation":[{"name":"Ghent University Hospital, Ghent, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Russel","sequence":"additional","affiliation":[{"name":"Queen\u2019s Hospital, Burton-on-Trent, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Gr\u00f6chenig","sequence":"additional","affiliation":[{"name":"Kantonspital Aurau, Aarau, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Basse","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Hvidovre University Hospital, Hvidovre, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Crespi","sequence":"additional","affiliation":[{"name":"Ospedale S. Rocco, Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Alikadic","sequence":"additional","affiliation":[{"name":"Division of Surgery, departement of Surgical Infection, University Medical Centre, Ljubljana, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Fraulin","sequence":"additional","affiliation":[{"name":"The Scarborough Hopsital, Scarborough, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.A.","family":"Dahl","sequence":"additional","affiliation":[{"name":"Wound and Skin Care Division, Coloplast A\/S, Humlebaek, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.P.","family":"Jemma","sequence":"additional","affiliation":[{"name":"Ribeir\u00e3o Preto, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5130","reference":[{"key":"p_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-4801.2005.00084.x"},{"key":"p_2","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2005.14.2.17441"},{"key":"p_3","unstructured":"Clinica; Issue: 1124: p10Clinical Trials or Literature Reviews? Get Real or Face Stricter Rules. www.clinicia .com C00857934,2004."},{"key":"p_5","volume-title":"Brookwood Medical Publications","author":"Introduction","year":"1996"},{"key":"p_8","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2003.12.9.26534"},{"key":"p_9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-4801.2005.00083.x"},{"key":"p_20","volume-title":"Pressure Ulcer Treatment Guidelines","author":"European Pressure Ulcer Advisory Panel","year":"1999"},{"key":"p_22","doi-asserted-by":"publisher","DOI":"10.1177\/107110078100200202"},{"key":"p_24","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2001.10.1.26038"},{"key":"p_27","volume-title":"Evidence from the EuroQol BIO MED Research Programme","author":"Perspective","year":"2003"},{"key":"p_28","volume-title":"Applied Analysis of Variance","author":"O'Brien R.G.","year":"1983"},{"key":"p_29","volume-title":"Practical Statistics for Medical Research","author":"Altman D.G.","year":"1992"},{"key":"p_36","volume-title":"At study conclusion it was 0.71 in the silver foam and 0.69 in the LBP group. The five categories (mobility","author":"At 0."},{"key":"p_55","unstructured":"Flanagan15indicated that percentage area reduction is an important indicator in differentiating between healing and non-healing wounds. A 20-40% reduction in wound area between two to four weeks is likely to be a reliable predictor of healing. It can be suggested that, as the relative wound area reduction was 28.8% in the LBP group after four weeks (Table 4), the wounds were not responding well to treatment; a 45.5% relative wound area reduction in the silver foam group is suggestive of a good response to treatment."},{"key":"p_63","unstructured":"Patient outcomes and quality of life are important parts of outcomes research.4In leg ulcer patients, the negative effect on quality of life is due to many interrelated factors including malodour, leakage, skin problems, pain, restricted mobility, lack of sleep and increased frequency of dressing and bandage changes.17-19Malodour, in particular, has a big impact on patients' psychological state and social life.20One of the main reasons for malodour is multiplication of and colonisation by bacteria.21The rapid disappearance of malodour observed in the silver foam group, when compared with LBP, could indicate that the sustained release of silver eliminates bacteria from the wound surface faster than LBP."},{"key":"p_68","volume-title":"S. Invisible wounds: the effects of skin ulcer malodours. J Wound Care 1994","author":"In"},{"key":"p_69","unstructured":"com\/2002\/march\/Naylor\/ Symptom-Control-Fungating-Wounds.html (March 2002)."},{"key":"p_72","first-page":"227","volume":"27","year":"2000","journal-title":"Continence Nursing"},{"key":"p_73","doi-asserted-by":"crossref","first-page":"365","DOI":"10.12968\/jowc.1998.7.7.365","volume":"7","author":"Price P","year":"1998","journal-title":"J Wound Care"},{"key":"p_75","doi-asserted-by":"publisher","DOI":"10.7748\/ns2000.06.14.40.71.c2865"},{"key":"p_78","doi-asserted-by":"crossref","unstructured":"instruments. 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