{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T06:19:02Z","timestamp":1777875542566,"version":"3.51.4"},"reference-count":11,"publisher":"Mark Allen Group","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2006,5]]},"abstract":"Objective:<\/jats:title> The primary objective was to compare the efficacy of a self-adherent soft silicone dressing (Mepiform) with \u2018left-alone\u2019 management of hypertrophic scars using the Vancouver Scar Scale. Secondary objectives were to follow photographs of the scars, patients\u2019 opinions of the scars, and doctors\u2019 and patients\u2019 assessments of the overall dressing performance, safety and tolerance. <\/jats:p><\/jats:sec>Method:<\/jats:title> An exploratory open randomised controlled clinical investigation was undertaken on 11 female patients aged 21\u201343 years with postoperative scars (nine following breast surgery, two following lower abdominal-glutealplasty). Treatment was initiated between two weeks and two months (mean 4.7 weeks) after surgery. Ten patients completed the 12-month investigation; one patient in the treatment group discontinued for personal reasons. <\/jats:p><\/jats:sec>Results:<\/jats:title> All parameters in the Vancouver Scar Scale improved in both groups, although patients treated with the soft silicone dressing showed greater and more rapid improvements compared with the non-treated patients, while their assessments of the condition of the scar were more favourable. Medical staff rated the overall dressing performance as \u2018very good\u2019 or \u2018good\u2019. One adverse event was reported \u2013 local skin irritation at the site of the scar. <\/jats:p><\/jats:sec>Conclusion:<\/jats:title> The results suggest that patients treated with the soft silicone dressing experienced greater and more rapid improvements compared with non-treated patients. These results concur with those of previous studies. The fact that Mepiform is self-adhesive and causes limited damage to the stratum corneum on removal gives it an added value compared with non-adhesive silicone gel dressings. <\/jats:p><\/jats:sec>Declaration of interest:<\/jats:title> This study was supported by M\u00f6lnlycke Health Care AB, Gothenburg, Sweden. <\/jats:p><\/jats:sec>","DOI":"10.12968\/jowc.2006.15.5.26913","type":"journal-article","created":{"date-parts":[[2014,5,23]],"date-time":"2014-05-23T15:59:18Z","timestamp":1400860758000},"page":"193-196","source":"Crossref","is-referenced-by-count":42,"title":["Evaluation of a self-adherent soft silicone dressing for the treatment of hypertrophic postoperative scars"],"prefix":"10.12968","volume":"15","author":[{"given":"J.I.","family":"Colom Maj\u00e1n","sequence":"first","affiliation":[{"name":"Special Sciences Institute, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5130","reference":[{"key":"p_13","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200208000-00031"},{"key":"p_14","doi-asserted-by":"publisher","DOI":"10.1097\/00004630-199509000-00013"},{"key":"p_15","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.326.7380.88"},{"key":"p_16","volume-title":"Karolinska Hospital","author":"Ekholm C.","year":"1998"},{"key":"p_19","volume-title":"Anaheim","year":"1999"},{"key":"p_21","unstructured":"Eleven female patients (six in the treatment and five in the control group) were randomised and enrolled into the study. In the dressing group the mean age was 28.8 years (range 20-43) and in the control group it was 29.4 years (range 22-40). Other demographic data are given in Table 1. Nine had had breast surgery and two lower abdominal-glutealplasty due to obesity. Treatment was initiated between two weeks and two months after surgery. Ten participants completed the 12-month investigation; one in the treatment group discontinued the study due to personal reasons."},{"key":"p_37","volume-title":"The use of Mepiform silicone dressing as treatment for hypertrophic scars. Poster presented at European Wound Management Association Congress","author":"Middelkoop E.","year":"2000"},{"key":"p_39","volume-title":"American Burn Association 33rd Annual Meeting","author":"Effectiveness","year":"2001"},{"key":"p_41","volume-title":"Poster at the 7th Annual Canadian","author":"Mepiform"},{"key":"p_42","volume-title":"Wound Care Conference in London","author":"Association of","year":"2001"},{"key":"p_43","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2001.10.2.26054"}],"container-title":["Journal of Wound Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/jowc.2006.15.5.26913","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T02:52:06Z","timestamp":1653360726000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/jowc.2006.15.5.26913"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,5]]},"references-count":11,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006,5]]}},"alternative-id":["10.12968\/jowc.2006.15.5.26913"],"URL":"https:\/\/doi.org\/10.12968\/jowc.2006.15.5.26913","relation":{},"ISSN":["0969-0700","2052-2916"],"issn-type":[{"value":"0969-0700","type":"print"},{"value":"2052-2916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,5]]}}}