{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,7,13]],"date-time":"2023-07-13T14:10:04Z","timestamp":1689257404110},"reference-count":23,"publisher":"Mark Allen Group","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:sec><jats:title>Objective:<\/jats:title><jats:p>To identify the microbial pathogens responsible for amputation wound infections, their distribution and antibiotic-sensitivity patterns.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method:<\/jats:title><jats:p>Consecutive patients who had limb amputations from April 2002 to March 2006 in an Nigerian hospital were recruited into this prospective observational study. The patients\u2019 demographic features, indications for amputation, microbiology of stump wound infections and the effects on length of hospital stay were reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Fifty-seven patients (mean age 34.6 \u00b1 19.2 years) had amputations in 58 limbs. Trauma leading to limb gangrene following treatment by traditional bone setters was the most common indication for amputation (64%). Approximately 76% of the amputations were in the lower limbs. Wound infection occurred in 48% of the stumps, of which 71% had been amputated because of a trauma injury. Pseudomonas aeruginosa was the most commonly isolated pathogen (40%). There was a very low correlation between the aetiologic bacterial agents and the age of patient, source of referral, indication for amputation and level of amputation. Amputation wound infections significantly prolonged the patients\u2019 length of hospital stay (p=0.002).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>Amputation wound infection constitutes a serious morbidity in our practice. Most of the causes are preventable.<\/jats:p><\/jats:sec><jats:sec><jats:title>Declaration of interest:<\/jats:title><jats:p>None.<\/jats:p><\/jats:sec>","DOI":"10.12968\/jowc.2008.17.5.29150","type":"journal-article","created":{"date-parts":[[2014,5,23]],"date-time":"2014-05-23T16:00:25Z","timestamp":1400860825000},"page":"202-206","source":"Crossref","is-referenced-by-count":3,"title":["Microbiology of amputation wound infection in a Nigerian setting"],"prefix":"10.12968","volume":"17","author":[{"given":"A.L.","family":"Akinyoola","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery and Traumatology, Obafemi Awolowo University, Ile-Ife, Nirgeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.D.","family":"Ojo","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Traumatology, Obafemi Awolowo University, Ile-Ife, Nirgeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.M.","family":"Oginni","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Traumatology, Obafemi Awolowo University, Ile-Ife, Nirgeria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5130","reference":[{"key":"p_1","first-page":"333","volume":"31","author":"Ogunlade S.O.","year":"2002","journal-title":"Afr J Med Med Sci"},{"key":"p_4","volume-title":"East Afr Med J 1998"},{"key":"p_6","first-page":"118","volume":"11","author":"Indications","year":"2002","journal-title":"Nigeria. 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Of these 50 limbs, only seven (14%) presented within 24 hours of the onset of gangrene: two (4%) within six hours and five (10%) with 6-24 hours."},{"key":"p_32","first-page":"335","volume":"21","author":"Omololu B.","year":"2002","journal-title":"West Afr J Med"},{"key":"p_33","doi-asserted-by":"publisher","DOI":"10.1080\/02724936.1995.11747766"},{"key":"p_34","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2000.16406"},{"key":"p_35","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2004.10.019"},{"key":"p_36","first-page":"5","volume":"62","author":"Huizinga W.K.","year":"1982","journal-title":"S Afr Med J"},{"key":"p_37","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.1989.tb01647.x"},{"key":"p_38","volume-title":"Practical Medical Microbiology","author":"Mackie T.J.","year":"1999","edition":"13"},{"key":"p_42","doi-asserted-by":"crossref","first-page":"176","DOI":"10.4103\/1117-1936.180540","volume":"13","year":"2006","journal-title":"Niger Postgrad Med J"},{"key":"p_43","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1302\/0301-620X.87B1.15585","volume":"87","author":"Eshete M","year":"2005","journal-title":"J Bone Joint Surg (Br)"},{"key":"p_44","unstructured":"The stumps of patients without wound infection (30 wounds) healed in a mean of 18.3 - 2SD (range 12-21), compared with 35.7 days 2SD in those with a wound infection (range 28-75) (p=0.032)."},{"key":"p_45","unstructured":"The mean hospital stay in patients without a wound infection was 26.7 - 12.3 days (range 14-36), compared with 42.3 - 18.1 days (range 28-84) in patients with a wound infection (p=0.002)."}],"container-title":["Journal of Wound Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/jowc.2008.17.5.29150","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,13]],"date-time":"2023-07-13T13:32:34Z","timestamp":1689255154000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/jowc.2008.17.5.29150"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5]]},"references-count":23,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["10.12968\/jowc.2008.17.5.29150"],"URL":"https:\/\/doi.org\/10.12968\/jowc.2008.17.5.29150","relation":{},"ISSN":["0969-0700","2052-2916"],"issn-type":[{"value":"0969-0700","type":"print"},{"value":"2052-2916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,5]]}}}