{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,4]],"date-time":"2025-05-04T00:36:27Z","timestamp":1746318987233},"reference-count":20,"publisher":"Mark Allen Group","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:sec><jats:title>Objective:<\/jats:title><jats:p>To evaluate the effect of ultrasound irradiation when used alongside standard care in the treatment of pressure ulcers; outcome measures were reduction in wound size and exudate weight.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method:<\/jats:title><jats:p>Five patients (two male and three female, age range: 76\u201392 years) with seven ulcers participated in this study. They had National Pressure Ulcer Advisory Panel (NPUAP) stage III or IV pressure ulcers. We conducted an ABABA study (A: standard treatment with dressings that promote a moist wound healing environment; B: ultrasound irradiation administered to the pressure ulcer through the same dressing used in period A; each period lasted 2\u20134 weeks). Six ulcers each were randomised to either the treatment group or control group. One ulcer was not randomised, but was the first to receive ultrasound in the BABA sequence, with a view to determining if the pilot was feasible. The control group received sham ultrasound in period B. Pulsed ultrasound (20% duty cycle, 0.5W\/cm<jats:sup>2<\/jats:sup>on the wound surface, 1MHz or 3MHz, for 10 minutes) was applied five times weekly.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>In the treatment group, two ulcers markedly decreased in size after 3\u20134 weeks of US treatment, one ulcer decreased in size soon after initiation of treatment and one ulcer showed no clear reduction in size. The volume of exudate was greater in period B than A in two ulcers that reduced markedly in size after 3\u20134 weeks of US treatment. None of the ulcers in the control group decreased markedly in size.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>This pilot study suggests that US used alongside standard treatment might promote the healing of pressure ulcers. However, larger studies are required to determine the effi cacy and mechanism of US treatment for PUs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Declaration of interest:<\/jats:title><jats:p>None.<\/jats:p><\/jats:sec>","DOI":"10.12968\/jowc.2010.19.2.46968","type":"journal-article","created":{"date-parts":[[2014,5,23]],"date-time":"2014-05-23T15:57:30Z","timestamp":1400860650000},"page":"63-68","source":"Crossref","is-referenced-by-count":8,"title":["Evaluation of the combined use of ultrasound irradiation and wound dressing on pressure ulcers"],"prefix":"10.12968","volume":"19","author":[{"given":"N.","family":"Maeshige","sequence":"first","affiliation":[{"name":"Division of Nutrition and Metabolism, Department of Biophysics, Kobe University Graduate School of Health Sciences, Kobe, Japan and Department of Rehabilitation, Eikokai Doi Hospital, Ono, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Fujiwara","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Eikokai Doi Hospital, Ono, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Honda","sequence":"additional","affiliation":[{"name":"Division of Health Sciences, Department of Community Health Sciences, Kobe University Graduate School of Health Sciences, Kobe, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Yoshikawa","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Nakayama Surgical Clinic, Akashi, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Terashi","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Usami","sequence":"additional","affiliation":[{"name":"Division of Nutrition and Metabolism, Department of Biophysics, Kobe University Graduate School of Health Sciences, and Department of Nutrition, Kobe University Hospital, Kobe, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Sugimoto","sequence":"additional","affiliation":[{"name":"Division of Health Sciences, Department of Community Health Sciences, Kobe University Graduate School of Health Sciences, Kobe, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5130","reference":[{"key":"p_3","doi-asserted-by":"publisher","DOI":"10.1006\/cyto.1998.0444"},{"key":"p_4","first-page":"11","volume":"21","author":"Sugimoto M.","year":"2006","journal-title":"Bull Health Sci Kobe"},{"key":"p_5","first-page":"D001275","volume":"4","author":"Baba-Akbari Sari A.","year":"2000","journal-title":"Cochrane Database Syst Rev"},{"key":"p_7","volume-title":"Health Technol Assess 2001"},{"key":"p_8","first-page":"40","volume":"48","author":"Selkowitz D.M.","year":"2002","journal-title":"Ostomy Wound Manage"},{"key":"p_9","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1093\/ptj\/76.12.1301","volume":"76","author":"Riet G.","year":"1996","journal-title":"Phys Ther"},{"key":"p_10","first-page":"66","volume":"71","author":"Mcdiarmid T.","year":"1985","journal-title":"Physiotherapy"},{"key":"p_11","doi-asserted-by":"crossref","first-page":"195","DOI":"10.2340\/165019779022195197","volume":"22","author":"Lundeberg T.","year":"1990","journal-title":"Scand J Rehab Med"},{"key":"p_12","doi-asserted-by":"crossref","first-page":"211","DOI":"10.2340\/165019779123211213","volume":"23","author":"Eriksson S.V.","year":"1991","journal-title":"Scand J Rehab Med"},{"key":"p_13","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(03)00285-X"},{"key":"p_14","first-page":"508","volume":"9","author":"Sugimoto M.","year":"2007","journal-title":"Jpn J PU"},{"key":"p_15","first-page":"98","volume-title":"Vol 1","author":"Joseph A.M.","year":"1990"},{"key":"p_16","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2003.10.024"},{"key":"p_18","unstructured":"Butterworth Heinemann, 2000."},{"key":"p_20","first-page":"371","volume":"40","author":"Physical","year":"2006","journal-title":"Rigaku Ryoho Janaru"},{"key":"p_21","volume-title":"Wound Care: A Collaborative Practice Manual for Physical Therapists and Nurses. 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