{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T14:13:11Z","timestamp":1790863991958,"version":"4.1.0"},"reference-count":5,"publisher":"Mark Allen Group","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2010,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p> To determine the effectiveness of Flammac\u00e9rium, a topical treatment used in the treatment of burns, in the stabilisation of necrosis in non-healing wounds. The therapy is designed to prevent the risk of infection, stop necrosis from spreading and improve the patient's quality of life. <\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p> This retrospective survey involved patients with necrotic, non-healing wounds who had been treated with Flammac\u00e9rium. In all cases, debridement was contraindicated. Available data on wound evolution were collected. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> Ninety-nine patient files were analysed and the wound aetiologies included in the survey were classified as arterial (n=42), malignant (n=5), pressure ulcers (n=30), traumatic wounds (n=10) and other wounds (n=12). The formation of a leather-like eschar induced by topical use of Flammac\u00e9rium improved pain management, decreased exudate levels and malodour, and had a positive effect on quality of life, increasing patient comfort, participation in social activity and psychological wellbeing. Following application of the cream, an eschar develops that strongly adheres to wound edges. By preventing the necrosis from spreading, this gave the practitioners more time to prepare for subsequent treatment, including skin grafting. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p> Flammac\u00e9rium seems to be effective in the stabilisation of necrosis in non-healing wounds in which debridement is contraindicated. However, this study is limited by its retrospective nature. A prospective study will hopefully confirm and strengthen these results. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conflict of interest<\/jats:title><jats:p> None <\/jats:p><\/jats:sec>","DOI":"10.12968\/jowc.2010.19.9.78219","type":"journal-article","created":{"date-parts":[[2014,5,23]],"date-time":"2014-05-23T16:00:15Z","timestamp":1400860815000},"page":"369-378","source":"Crossref","is-referenced-by-count":9,"title":["Flammacrium in the formation and stabilisation of eschar in chronic wounds"],"prefix":"10.12968","volume":"19","author":[{"given":"C.","family":"Signe-Picard","sequence":"first","affiliation":[{"name":"Wound Healing Unit; Lapeyronie Hospital, University Hospital Centre of Montpellier, 295 Av. Doyen G. Giraud, 34295 Montpellier, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M-I.","family":"Cerdan","sequence":"additional","affiliation":[{"name":"Wound Healing Unit; Lapeyronie Hospital, University Hospital Centre of Montpellier, 295 Av. Doyen G. Giraud, 34295 Montpellier, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Naggara","sequence":"additional","affiliation":[{"name":"Hospital Pharmacy; Lapeyronie Hospital, University Hospital Centre of Montpellier, 295 Av. Doyen G. Giraud, 34295 Montpellier, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Trial","sequence":"additional","affiliation":[{"name":"Wound Healing Unit; Lapeyronie Hospital, University Hospital Centre of Montpellier, 295 Av. Doyen G. Giraud, 34295 Montpellier, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"T\u00e9ot","sequence":"additional","affiliation":[{"name":"Wound Healing Unit; Lapeyronie Hospital, University Hospital Centre of Montpellier, 295 Av. Doyen G. Giraud, 34295 Montpellier, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5130","reference":[{"key":"p_1","volume-title":"Carretto, e."},{"key":"p_3","doi-asserted-by":"publisher","DOI":"10.1179\/joc.1998.10.1.17"},{"key":"p_4","volume-title":"monography Flammac\u00e9rium.vidal 2008 3 Angelotti, n., martini","year":"1997"},{"key":"p_5","doi-asserted-by":"crossref","unstructured":"bactericidal ability of silver cations.Water res 2007; 41: 18, 4097-4104. 5 Herruzo-Cabrera r., Garcia-torres v., rey-Calero J.,vizcaino-Alcaide m.J. evaluation of the penetration strength, bactericidal efficacy and spectrum of action of several antimicrobial creams against isolated microorganisms in a burn centre. burns. 1992; 18: 1, 39-44.","DOI":"10.1016\/0305-4179(92)90118-E"},{"key":"p_7","unstructured":"First period (1-3 days"}],"container-title":["Journal of Wound Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/jowc.2010.19.9.78219","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T02:40:27Z","timestamp":1653360027000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/jowc.2010.19.9.78219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9]]},"references-count":5,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["10.12968\/jowc.2010.19.9.78219"],"URL":"https:\/\/doi.org\/10.12968\/jowc.2010.19.9.78219","relation":{},"ISSN":["0969-0700","2052-2916"],"issn-type":[{"value":"0969-0700","type":"print"},{"value":"2052-2916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,9]]}}}