{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T03:04:16Z","timestamp":1788923056188,"version":"build-2803163510"},"reference-count":27,"publisher":"Mark Allen Group","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2018,3,2]]},"abstract":"<jats:sec><jats:title>Objective:<\/jats:title><jats:p> To estimate whether a collagen-containing dressing could potentially afford the UK's National Health Service (NHS) a cost-effective intervention for the management of diabetic foot ulcers (DFUs). <\/jats:p><\/jats:sec><jats:sec><jats:title>Method:<\/jats:title><jats:p> A decision model depicting the management of a DFU was constructed and populated with a combination of published clinical outcomes, resource use estimates and utilities for DFUs. The model estimated the incremental cost-effectiveness of a collagen-containing dressing plus standard care compared with standard care alone over a period of four months in terms of the incremental cost per quality-adjusted life year (QALY) gained. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> Treatment of DFUs of &gt;6 months duration with a collagen-containing dressing plus standard care instead of standard care alone is expected to increase the probability of healing from 0.08 to 0.53 by four months and increase health-related quality of life at four months from 0.156 to 0.163 QALYs per patient. Additionally, treatment with a collagen-containing dressing has the potential to reduce management costs by 22% over four months when compared with standard care alone (from \u00a32897 to \u00a32255 per patient). Treatment of new DFUs with a collagen-containing dressing plus standard care instead of standard care alone was also found to improve outcomes for less cost. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> Within the study's limitations, use of a collagen-containing dressing plus standard care instead of standard care alone potentially affords the NHS a cost-effective (dominant) treatment for both non-healing and new DFUs, since it improves outcomes for less cost. Hence, protocols should be established which enable clinicians to effectively introduce collagen-containing dressings into care pathways and monitor response to treatment. <\/jats:p><\/jats:sec>","DOI":"10.12968\/jowc.2018.27.3.136","type":"journal-article","created":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T15:21:41Z","timestamp":1520349701000},"page":"136-144","source":"Crossref","is-referenced-by-count":12,"title":["Potential cost-effectiveness of using a collagen-containing dressing in managing diabetic foot ulcers in the UK"],"prefix":"10.12968","volume":"27","author":[{"given":"Julian F.","family":"Guest","sequence":"first","affiliation":[{"name":"Catalyst Health Economics Consultants, Rickmansworth, Hertfordshire, UK; and Faculty of Life Sciences and Medicine, King's College, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heenal","family":"Singh","sequence":"additional","affiliation":[{"name":"Catalyst Health Economics Consultants, Rickmansworth, Hertfordshire, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Vowden","sequence":"additional","affiliation":[{"name":"Bradford Teaching Hospitals NHS Foundation Trust and University of Bradford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5130","reference":[{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2015-009283"},{"issue":"12","key":"B3","first-page":"322","volume":"14","author":"Guest JF","year":"2016","journal-title":"Int Wound J"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12816"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2004.01375.x"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1007\/s13300-012-0004-9"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2017.26.6.292"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000305463.32800.32"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000414705.56138.65"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.137.7.822"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-739X(07)71657-3"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdiacomp.2007.03.006"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.3402\/dfa.v6.24999"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12357"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.134.3.293"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12020"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1177\/1534734609331597"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2003.12.Sup3.11432"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1097\/WON.0b013e31822ad290"},{"issue":"3","key":"B20","volume":"1","author":"Cullen B","year":"2010","journal-title":"Wounds International"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.2147\/DMSO.S36024"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2008.17.2.28181"},{"issue":"1","key":"B23","first-page":"1","volume":"8","author":"Westgate S","year":"2012","journal-title":"Wounds UK"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-475X.1999.00201.x"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.24.2.290"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2002.11.2.26675"},{"key":"B27","first-page":"4","volume":"56","author":"L\u00e1zaro-Mart\u00edne JL","year":"2010","journal-title":"Ostomy Wound Manage"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2017.26.Sup1.S12"}],"container-title":["Journal of Wound Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/jowc.2018.27.3.136","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T21:32:31Z","timestamp":1653427951000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/jowc.2018.27.3.136"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,2]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3,2]]}},"alternative-id":["10.12968\/jowc.2018.27.3.136"],"URL":"https:\/\/doi.org\/10.12968\/jowc.2018.27.3.136","relation":{},"ISSN":["0969-0700","2052-2916"],"issn-type":[{"value":"0969-0700","type":"print"},{"value":"2052-2916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,2]]}}}