{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T15:28:31Z","timestamp":1771169311113,"version":"3.50.1"},"reference-count":28,"publisher":"Mark Allen Group","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2020,11,2]]},"abstract":"<jats:sec><jats:title>Objective:<\/jats:title><jats:p> To examine the effect of a nanocolloidal silver-based gel called SilvoGel (ChitoTech, Iran) versus eosin (prepared by Razi Hospital, Iran) among patients with immunobullous disease. <\/jats:p><\/jats:sec><jats:sec><jats:title>Method:<\/jats:title><jats:p> This blind, randomised controlled study was carried out on patients with pemphigus vulgaris who had hard-to-heal ulcers, divided into two equal-sized groups: one treatment group receiving the nanocolloidal silver-based gel and the control group receiving the conventional eosin. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> A total of 32 patients participated in the study. In both the treatment and control groups, ulcer area, exudate and tissue type improved significantly (p&lt;0.001 for all measures). A significantly higher rate of improvement in ulcer area was observed in the treatment group compared with the control group (p&lt;0.001). Both patient and physician satisfaction were significantly higher in the treatment group compared with the control group (p=0.003 and p=0.01, respectively). <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> The results of this study indicate that use of the nanocolloidal silver-based gel for treating patients with immunobullous disease including pemphigus could potentially increase the rate and quality of wound healing. <\/jats:p><\/jats:sec>","DOI":"10.12968\/jowc.2020.29.11.664","type":"journal-article","created":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T19:03:20Z","timestamp":1605121400000},"page":"664-668","source":"Crossref","is-referenced-by-count":8,"title":["Comparison of topical nanocolloidal silver formulation use with eosin 2% solution in management of hard-to-heal ulcers in patients with pemphigus vulgaris"],"prefix":"10.12968","volume":"29","author":[{"given":"Robabeh","family":"Abedini","sequence":"first","affiliation":[{"name":"Tehran University of Medical Sciences, Dermatology Department, Razi Hospital, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamidreza","family":"Mahmoudi","sequence":"additional","affiliation":[{"name":"Tehran University of Medical Sciences, Dermatology Department, Razi Hospital, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soheila","family":"Kordestani","sequence":"additional","affiliation":[{"name":"Medical Engineering Department, Amirkabir University of Technology, Tehran, Iran."},{"name":"ChitoTech Inc, Unit 9&11, East Wing, No. 83, Khaghani Building, Somayeh Avenue, Tehran, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farzaneh Nayeb","family":"Habib","sequence":"additional","affiliation":[{"name":"Medical Engineering Department, Amirkabir University of Technology, Tehran, 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