{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:06:30Z","timestamp":1791893190594,"version":"4.3.4"},"reference-count":37,"publisher":"Mark Allen Group","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2026,10,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This study aims to compare vacuum-assisted closure (VAC) and conventional wound dressings in patients with necrotising fasciitis (NF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>In this retrospective study, patients presenting with soft tissue infection and who were diagnosed with NF were enrolled, and divided into those treated with VAC therapy after the first surgical debridement (VAC group) and those patients treated with conventional dressing after surgery (non-VAC group).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 72 patients were included (43 patients in the VAC group and 29 patients in the non-VAC group). In the VAC group, VAC dressings were changed every 3\u20135 days, and patients had an average of five (range: 3\u20138) treatment sessions with an average hospital stay of 22.3 days (range: 14\u201339 days). In the non-VAC group, patients had an average of nine (range: 6\u201314) treatment sessions with five (range: 3\u20138) dressing changes every day during treatment, and had longer lengths of hospital stay of 41.1 days (range: 29\u201384 days). When compared to the non-VAC group, patients treated with VAC had a lower mortality rate and enabled the use of a simpler method of wound reconstruction (such as direct suture or skin graft).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In this study, findings showed that VAC therapy promoted infection control, reduced daily nursing care and increased wound healing, and patients had a shorter hospital stay and lower mortality rate.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.12968\/jowc.2021.0052","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T17:56:37Z","timestamp":1791395797000},"page":"958-964","source":"Crossref","is-referenced-by-count":0,"title":["Vacuum-assisted closure therapy in the management of patients with necrotising fasciitis"],"prefix":"10.12968","volume":"35","author":[{"given":"Fei","family":"Long","sequence":"first","affiliation":[{"name":"Plastic and Aesthetic Surgery Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elan","family":"Yang","sequence":"additional","affiliation":[{"name":"Plastic and Aesthetic Surgery Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Wang","sequence":"additional","affiliation":[{"name":"Plastic and Aesthetic Surgery Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhifei","family":"Liu","sequence":"additional","affiliation":[{"name":"Plastic and Aesthetic Surgery Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huaiwu","family":"He","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Unit, Peking Union Medical College Hospital, Chinese Academy of Medical Science And Peking Union Medical College, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3043-0020","authenticated-orcid":false,"given":"Xiaojun","family":"Wang","sequence":"additional","affiliation":[{"name":"Plastic and Aesthetic Surgery Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5130","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-021-06928-5"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2019.01.014"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/ta.0000000000002636"},{"issue":"1","key":"e_1_3_2_4_2","first-page":"76","article-title":"Use of a vacuum-assisted device for Fournier's gangrene: a new paradigm","volume":"10","author":"Silberstein J","year":"2008","unstructured":"Silberstein J, Grabowski J, Parsons JK. Use of a vacuum-assisted device for Fournier's gangrene: a new paradigm. Rev Urol 2008; 10(1):76\u201380","journal-title":"Rev Urol"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/1749-7922-6-46"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-199706000-00001"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-199706000-00002"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-020-03170-7"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2018.08.016"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0021-7697(07)91959-6"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2004.03.022"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.08.054"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2019.277"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1308\/rcsann.2019.0013"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-018-5096-z"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2008.07.053"},{"issue":"5","key":"e_1_3_2_17_2","first-page":"397","article-title":"Aggressive surgical management of necrotizing fasciitis serves to decrease mortality: a retrospective study\/discussion","volume":"64","author":"Bilton BD","year":"1998","unstructured":"Bilton BD, Zibari GB, McMillan RW et al. Aggressive surgical management of necrotizing fasciitis serves to decrease mortality: a retrospective study\/discussion. Am Surg 1998; 64(5):397\u2013400","journal-title":"Am Surg"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200308000-00005"},{"issue":"10","key":"e_1_3_2_19_2","first-page":"981","article-title":"Necrotizing fasciitis","volume":"55","author":"Puvanendran R","year":"2009","unstructured":"Puvanendran R, Huey JCM, Pasupathy S. Necrotizing fasciitis. Can Fam Physician 2009; 55(10):981\u2013987","journal-title":"Can Fam Physician"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1056\/nejm198406283102601"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-017-4145-x"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-019-06103-0"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ccm.0000129486.35458.7d"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.5811\/westjem.2017.3.33607"},{"issue":"9","key":"e_1_3_2_25_2","first-page":"488","article-title":"[Vacuum sealing as treatment of soft tissue damage in open fractures] [inGerman]","volume":"96","author":"Fleischmann W","year":"1993","unstructured":"Fleischmann W, Strecker W, Bombelli M, Kinzi L. [Vacuum sealing as treatment of soft tissue damage in open fractures] [inGerman]. Unfallchirurg 1993; 96(9):488\u2013492","journal-title":"Unfallchirurg"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0007-1226(97)91369-2"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199706000-00014"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0003-4975(99)01159-5"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12301"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-481X.2012.01008.x"},{"issue":"11","key":"e_1_3_2_31_2","first-page":"408","article-title":"The effect of a bacteria-and fungi-binding mesh dressing on the bacterial load of pressure ulcers treated with negative pressure wound therapy: a pilot study","volume":"28","author":"Ciliberti M","year":"2016","unstructured":"Ciliberti M, De Lara F, Serra G et al. The effect of a bacteria-and fungi-binding mesh dressing on the bacterial load of pressure ulcers treated with negative pressure wound therapy: a pilot study. Wounds 2016; 28(11):408\u2013420","journal-title":"Wounds"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2016.25.3.154"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.sap.0000187182.90907.3d"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2008.04.018"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199912000-00031"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1015-9584(09)60072-5"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2007.06.023"}],"container-title":["Journal of Wound Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/jowc.2021.0052","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T11:40:41Z","timestamp":1791891641000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/jowc.2021.0052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,2]]},"references-count":37,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10,2]]}},"alternative-id":["10.12968\/jowc.2021.0052"],"URL":"https:\/\/doi.org\/10.12968\/jowc.2021.0052","relation":{},"ISSN":["0969-0700","2052-2916"],"issn-type":[{"value":"0969-0700","type":"print"},{"value":"2052-2916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,2]]}}}