{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:45:24Z","timestamp":1792813524637,"version":"4.5.0"},"reference-count":34,"publisher":"Mark Allen Group","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2022,11,2]]},"abstract":"<jats:sec><jats:title>Objective:<\/jats:title><jats:p>Silver dressings have been used in the treatment of diabetic foot ulcers (DFUs). However, meta-analyses examining their effectiveness is lacking. Therefore, this meta-analysis evaluates the effectiveness of silver dressings on DFU healing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method:<\/jats:title><jats:p>Various databases were searched for randomised controlled trials (RCTs) of silver dressing applied to DFUs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>A total of seven studies involving 650 patients were identified for inclusion in the meta-analysis. The odds ratio (OR) for silver dressing improving wound healing rate, complete healing time, ulcer-related in-hospital time and infection resolution rate were: 4.02 (95% confidence interval [CI]: 2.25\u20137.17; p&lt;0.01); 2.81 (95% CI: \u20133.33\u2013\u20132.29; p&lt;0.01); 12.13 (95% CI:\u201320.64\u2013\u20133.62; p&lt;0.01); and 7.36 (95% CI: 1.58\u201334.22; p=0.01), respectively. The OR on ulcer area reduction was 8.60 (95% CI:\u20138.93\u201326.12; p=0.34) indicating no significant effect.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>The results of this meta-analysis showed that silver dressings enhance DFU healing rate, shorten the time to complete healing, shorten in-hospital duration, and improve infection resolution rate, while having no significant effect on reduction of ulcer area. Large-scale, multicentre, rigorously designed RCTs are recommended for future investigation to justify the beneficial effects of silver dressings on DFU healing.<\/jats:p><\/jats:sec>","DOI":"10.12968\/jowc.2022.31.11.979","type":"journal-article","created":{"date-parts":[[2022,11,11]],"date-time":"2022-11-11T17:30:19Z","timestamp":1668187819000},"page":"979-986","source":"Crossref","is-referenced-by-count":25,"title":["Effectiveness of silver dressings in the treatment of diabetic foot ulcers: a systematic review and meta-analysis"],"prefix":"10.12968","volume":"31","author":[{"given":"YiXin","family":"Luo","sequence":"first","affiliation":[{"name":"School of Nursing, Sun Yat-sen University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Li","sequence":"additional","affiliation":[{"name":"Emergency Department, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 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