{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T08:46:24Z","timestamp":1774082784967,"version":"3.50.1"},"reference-count":10,"publisher":"Mark Allen Group","issue":"Sup3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2022,3,1]]},"abstract":"<jats:p> A growing body of evidence supports the use of topical oxygen therapy (TOT) in the treatment of diabetic foot ulcers (DFUs). In addition, anecdotal evidence suggests that topical oxygen may be effective in the treatment of other wound types. In May 2021, experts in the field of wound healing from across the US assembled in New Orleans for the inaugural Leaders in Wound Healing conference. In an interactive session dedicated to TOT, several physicians presented and debated the evidence for TOT. Experts in the audience also shared their experiences in treating patients with TOT. The consensus of the experts recommended the use of TOT in DFUs and supported payer reimbursement for the modality. However, they stressed the need for a guidance document on the use of TOT in patients with hard-to-heal wounds. Following the conference, a Delphi method was employed to establish consensus guidelines for prescribing TOT. A multidisciplinary panel of 24 wound experts (15 wound specialists, six vascular surgeons, one plastic surgeon, one critical care provider and one PhD researcher) participated in two rounds of questionnaires. The Delphi survey questions focused on the indications for topical oxygen, when to prescribe the therapy, pretreatment work-up, visit frequency and length of therapy. A clinical workflow algorithm was also included as part of the Delphi. After two rounds, the Delphi participants were able to reach consensus of &gt;77% on when to prescribe topical oxygen, the wound types that may benefit from the therapy, pretreatment wound preparation and work-up and length of therapy. The goal of the guidelines is to standardise the use of topical oxygen and inform further research efforts. <\/jats:p>","DOI":"10.12968\/jowc.2022.31.sup3.s20","type":"journal-article","created":{"date-parts":[[2022,2,24]],"date-time":"2022-02-24T12:42:16Z","timestamp":1645706536000},"page":"S20-S24","source":"Crossref","is-referenced-by-count":12,"title":["Guidelines for the use of topical oxygen therapy in the treatment of hard-to-heal wounds based on a Delphi consensus"],"prefix":"10.12968","volume":"31","author":[{"given":"Thomas E","family":"Serena","sequence":"first","affiliation":[{"name":"SerenaGroup Research Foundation, Cambridge, MA, US"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Andersen","sequence":"additional","affiliation":[{"name":"Wound Care Clinic, Madigan Army Medical Center, WA, US"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Windy","family":"Cole","sequence":"additional","affiliation":[{"name":"Kent State University College of Podiatric Medicine, OH, US"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Garoufalis","sequence":"additional","affiliation":[{"name":"Professional Foot Care Specialists, PC, Chicago, IL, US"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Frykberg","sequence":"additional","affiliation":[{"name":"Diabetic Foot Consultants, LLC, Fountain Hills, AZ, US"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Simman","sequence":"additional","affiliation":[{"name":"Wright State University and University of Toledo, OH, US"},{"name":"Jobst Vascular Institute, ProMedica Health Network, Toledo, OH, US"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5130","reference":[{"issue":"5","key":"B1","doi-asserted-by":"crossref","first-page":"S38","DOI":"10.1016\/S0002-9610(03)00303-9","volume":"187","author":"Gottrup F.","year":"2004","journal-title":"Am J Surg"},{"issue":"3","key":"B2","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1089\/wound.2017.0743","volume":"7","author":"Fife CE","year":"2018","journal-title":"Adv Wound Care"},{"issue":"1","key":"B3","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jval.2017.07.007","volume":"21","author":"Nussbaum SR","year":"2018","journal-title":"Value Health"},{"key":"B4","doi-asserted-by":"crossref","first-page":"S30","DOI":"10.12968\/jowc.2018.27.Sup9.S30","volume":"27","author":"Niederauer MQ","year":"2018","journal-title":"J Wound Care"},{"issue":"3","key":"B5","doi-asserted-by":"crossref","first-page":"616","DOI":"10.2337\/dc19-0476","volume":"43","author":"Frykberg RG","year":"2020","journal-title":"Diabetes Care"},{"key":"B6","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.12968\/jowc.2021.30.Sup5.S7","volume":"30","author":"Serena TE","year":"2021","journal-title":"J Wound Care"},{"issue":"8","key":"B7","doi-asserted-by":"crossref","first-page":"e14585","DOI":"10.1111\/dme.14585","volume":"38","author":"Thanigaimani S","year":"2021","journal-title":"Diabet Med"},{"issue":"1","key":"B8","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/s12874-016-0165-8","volume":"16","author":"Eubank BH","year":"2016","journal-title":"BMC Med Res Methodol"},{"issue":"6","key":"B9","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1097\/PRS.0b013e3182a80586","volume":"132","author":"Kim PJ","year":"2013","journal-title":"Plast Reconstr Surg"},{"issue":"3","key":"B10","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1111\/j.1524-475X.2012.00790.x","volume":"20","author":"Serena TE","year":"2012","journal-title":"Wound Repair Regen"}],"container-title":["Journal of Wound Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/jowc.2022.31.Sup3.S20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,24]],"date-time":"2022-02-24T12:43:55Z","timestamp":1645706635000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/jowc.2022.31.Sup3.S20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,1]]},"references-count":10,"journal-issue":{"issue":"Sup3","published-print":{"date-parts":[[2022,3,1]]}},"alternative-id":["10.12968\/jowc.2022.31.Sup3.S20"],"URL":"https:\/\/doi.org\/10.12968\/jowc.2022.31.sup3.s20","relation":{},"ISSN":["0969-0700","2052-2916"],"issn-type":[{"value":"0969-0700","type":"print"},{"value":"2052-2916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,1]]}}}