{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T15:49:37Z","timestamp":1749743377656,"version":"3.40.5"},"reference-count":15,"publisher":"Mark Allen Group","issue":"Sup5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2025,5,1]]},"abstract":"<jats:sec><jats:title>Objective:<\/jats:title><jats:p> To compare transcutaneous oxygen measurement (TCOM) and near infrared spectroscopy (NIRS) measurement of tissue oxygen levels in hard-to-heal (chronic) wounds. <\/jats:p><\/jats:sec><jats:sec><jats:title>Method:<\/jats:title><jats:p> Patients aged 18\u201385 years presenting with hard-to-heal lower extremity wounds between 1 December 2019 and 31 July 2020 were included in this cross-sectional study. TCOM and NIRS measurements of tissue oxygenation were obtained. Data were stratified by wound severity (Wagner score), skin pigmentation (Fitzpatrick skin type), and use of melanin correction for NIRS measurement. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> A total of 76 patients were included. Correlation coefficients between TCOM and NIRS with melanin correction were obtained for: Fitzpatrick I\u2013III (p=0.41); Fitzpatrick IV\u2013VI (p=0.08); Wagner 0\u20132 (p=0.22); Wagner 3\u20135 (p=0.34). Results without melanin correction were: Fitzpatrick I\u2013III (p=0.19); Fitzpatrick IV\u2013VI (p=0.08); Wagner 0\u20132 (p=0.05); and Wagner 3\u20135 (p=0.34). <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> There was only one significant correlation between TCOM and NIRS measurements of tissue oxygenation in patients with hard-to-heal lower extremity wounds and that was for patients with Wagner scores of 0\u20132 without melanin correction. Further investigation is needed on the application of NIRS to guide the interventional management of hard-to-heal wounds. <\/jats:p><\/jats:sec>","DOI":"10.12968\/jowc.2023.0022","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T13:56:46Z","timestamp":1747144606000},"page":"S26-S32","source":"Crossref","is-referenced-by-count":1,"title":["Comparing oxygenation assessment methods for the interventional management of hard-to-heal wounds"],"prefix":"10.12968","volume":"34","author":[{"given":"Caroline","family":"Mussatto","sequence":"first","affiliation":[{"name":"School of Medicine, University of Kansas Medical Center, Kansas, US"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Nygard","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Kansas Medical Center, Kansas, US"},{"name":"MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kris","family":"Butler","sequence":"additional","affiliation":[{"name":"Hyperbaric Medicine\/Outpatient Burn and Wound Clinic University of Kansas Hospital, Kansas, US"},{"name":"RN, BSN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas","family":"Richards","sequence":"additional","affiliation":[{"name":"School of Medicine, University of Kansas Medical Center, Kansas, US"},{"name":"MS, MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brenden","family":"Bombardier","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Kansas Medical Center, Kansas, US"},{"name":"MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren","family":"Clark","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Data Science, University of Kansas Medical Center, Kansas, US"},{"name":"MS"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanming","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Data Science, University of Kansas Medical Center, Kansas, US"},{"name":"PhD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate","family":"Young","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Data Science, University of Kansas Medical Center, Kansas, US"},{"name":"MS"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carissa","family":"Walter","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Kansas Medical Center, Kansas, US"},{"name":"MPH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peyton","family":"Ackerman","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Kansas Medical Center, Kansas, US"},{"name":"BA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Orr","sequence":"additional","affiliation":[{"name":"School of Medicine, University of Kansas Medical Center, Kansas, US"},{"name":"Hyperbaric Medicine\/Outpatient Burn and Wound Clinic University of Kansas Hospital, Kansas, US"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron","family":"Rohr","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Kansas Medical Center, Kansas, US"},{"name":"MS, MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamal","family":"Gupta","sequence":"additional","affiliation":[{"name":"Hyperbaric Medicine\/Outpatient Burn and Wound Clinic University of Kansas Hospital, Kansas, US"},{"name":"MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Alli","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Kansas Medical Center, Kansas, US"},{"name":"MD"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5130","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1089\/wound.2015.0635"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1080\/13696998.2023.2232256"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12356"},{"key":"B4","unstructured":"Ercengiz A, Mutluoglu M. Hyperbaric transcutaneous oximetry. StatPearls Publishing, 2023"},{"issue":"2","key":"B5","first-page":"1006","volume":"1","author":"Bowen RE","year":"2016","journal-title":"SM Vasc Med"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpm.2018.02.005"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000005669"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1109\/TRPMS.2020.3009913"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.472568"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1007\/s10877-013-9507-9"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.2.003047"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1177\/107110078100200202"},{"key":"B13","unstructured":"Sharma AN, Patel BC. Laser Fitzpatrick skin type recommendations. 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