{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T12:10:43Z","timestamp":1779019843034,"version":"3.51.4"},"reference-count":29,"publisher":"Mark Allen Group","issue":"Sup5a","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2026,5,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To determine the effectiveness of Biodress (a petroleum-based hydrogen-calcium salt of oxidised cellulose dressing made of organic materials; Bottu, Morocco) against both honey and povidone-iodine ointment on wound closure, the incidence of wound complications, the cost of wound care, ease of use, and the outcome of acute wounds.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>A single-blinded randomised controlled trial (RCT) was performed among patients with acute wounds selected from two hospitals in southeast Nigeria. Participants were randomised with computer-generated numbers into one of three equally-sized groups: the petroleum-based dressing used as the intervention, and either honey or povidone-iodine which were used as two independent control groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 42 patients were included in this RCT, median age 32.5 years, with 22 male and 20 female patients. No significant difference was observed in the effectiveness of the petroleum-based dressing over honey or povidone-iodine ointment on wound closure (p=0.288). However, considering injury type, Biodress showed some advantage over honey in burns injuries (p=0.017). None of the participants in the intervention group had wound infection at any of the follow-up visits. No significant difference was noted in the cost of dressing materials (dressing packs and cleansing solutions) (p=0.717), or in the cost of dressing agents (Biodress\/honey\/ povidone-iodine) (p=0.222). Similarly, there was no significant difference in the ease of use of the different materials. The petroleum-based dressing, however, was significantly less painful than the other dressing agents and required significantly fewer dressing materials per episode compared to the other dressings (p=0.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In this RCT, Biodress demonstrated its potential as a promising dressing agent for acute wounds, particularly burns injuries; however, further studies will help to substantiate or disprove this finding.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.12968\/jowc.2023.0159","type":"journal-article","created":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T11:51:13Z","timestamp":1777722673000},"source":"Crossref","is-referenced-by-count":0,"title":["Effectiveness of Biodress versus both honey and povidone-iodine ointment in acute wound healing in Enugu State, Nigeria: a randomised controlled trial"],"prefix":"10.12968","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5696-1044","authenticated-orcid":false,"given":"Chinenye J","family":"Anetekhai","sequence":"first","affiliation":[{"name":"Department of Nursing Sciences, Faculty of Health Sciences and Technology, University of Nigeria Enugu Campus, Nigeria."},{"name":"School of Nursing and Midwifery, Birmingham City University, City South Campus, Birmingham, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnes N","family":"Anarado","sequence":"additional","affiliation":[{"name":"Department of Nursing Sciences, Faculty of Health Sciences and Technology, University of Nigeria Enugu Campus, Nigeria."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilson I","family":"Anetekhai","sequence":"additional","affiliation":[{"name":"National Orthopaedic Hospital Enugu, Enugu State, Nigeria."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chinweuba U","family":"Anthonia","sequence":"additional","affiliation":[{"name":"Department of Nursing Sciences, Faculty of Health Sciences and Technology, University of Nigeria Enugu Campus, Nigeria."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uwakwe C","family":"Mba","sequence":"additional","affiliation":[{"name":"National Orthopaedic Hospital Enugu, Enugu State, Nigeria."},{"name":"Enugu State University of Science and Technology Teaching Hospital, Enugu State, Nigeria."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ifeanyi I","family":"Onah","sequence":"additional","affiliation":[{"name":"National Orthopaedic Hospital Enugu, Enugu State, Nigeria."},{"name":"Enugu State University of Science and Technology Teaching Hospital, Enugu State, Nigeria."},{"name":"Institute of Orthopaedics and Plastic Surgery, Abia State University, Nigeria."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulina C","family":"Chikeme","sequence":"additional","affiliation":[{"name":"Department of Nursing Sciences, Faculty of Health Sciences and Technology, University of Nigeria Enugu Campus, Nigeria."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5130","reference":[{"key":"e_1_3_3_1_2","doi-asserted-by":"publisher","DOI":"10.18203\/2349-2902.isj20151491"},{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-818422-6.00072-1"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000416006.55218.d0"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2017.06.073"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2006.32167.x"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001332"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bea.2022.100055"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000733724.87630.d6"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.2217\/cpr.13.50"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2021.30.Sup4.S28"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26164784"},{"issue":"4","key":"e_1_3_3_12_2","first-page":"219","article-title":"Influence of hydrogencalcium salts of oxidized cellulose on MMP-2, MMP-9 and TNF-\u03b1 production and wound healing in non-healing wounds","volume":"21","author":"Frankova J","year":"2013","unstructured":"Frankova J, Diamantova D, Vrbkova J, Ulrichova J. Influence of hydrogencalcium salts of oxidized cellulose on MMP-2, MMP-9 and TNF-\u03b1 production and wound healing in non-healing wounds. Acta Dermatovenerol Croat 2013; 21(4):219\u2013223","journal-title":"Acta Dermatovenerol Croat"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.11.011"},{"key":"e_1_3_3_14_2","unstructured":"National Bureau of Statistics. Nigeria launches its most extensive national measure of multidimensional poverty. 2022. https:\/\/tinyurl.com\/ms9ddjyf (accessed 11 February 2026)"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-019-4512-4"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00152192-200505002-00085"},{"issue":"4","key":"e_1_3_3_17_2","first-page":"44","article-title":"Reliability of wound measuring techniques in an outpatient wound center","volume":"47","author":"Bryant JL","year":"2001","unstructured":"Bryant JL, Brooks TL, Schmidt B, Mostow EN. Reliability of wound measuring techniques in an outpatient wound center. Ostomy Wound Manage 2001; 47(4):44\u201351","journal-title":"Ostomy Wound Manage"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-481X.2010.00765.x"},{"key":"e_1_3_3_19_2","volume-title":"EWMA Position Document. Identifying criteria for wound infection","author":"Cutting KF","year":"2005","unstructured":"Cutting KF, White RJ, Mahoney P, Harding KG. Clinical identification of wound infection: a Delphi Approach. In: EWMA Position Document. Identifying criteria for wound infection. Medical Education Partnership Ltd, 2005. https:\/\/tinyurl.com\/4b95dp7w (accessed 11 February 2026)"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-025-03224-w"},{"issue":"2","key":"e_1_3_3_21_2","first-page":"163","article-title":"Postoperative wound care after dermatologic procedures: a comparison of 2 commonly used petrolatum-based ointments","volume":"12","author":"Morales-Burgos A","year":"2013","unstructured":"Morales-Burgos A, Loosemore MP, Goldberg LH. Postoperative wound care after dermatologic procedures: a comparison of 2 commonly used petrolatum-based ointments. J Drugs Dermatol 2013; 12(2):163\u2013164","journal-title":"J Drugs Dermatol"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2014.07.024"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1089\/acm.2005.11.511"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0305-4179(97)00113-7"},{"issue":"3","key":"e_1_3_3_25_2","first-page":"140","article-title":"The antipseudomonal property of honey and gentamicin","volume":"19","author":"Adeleke OE","year":"2006","unstructured":"Adeleke OE, Olaitan PB. The antipseudomonal property of honey and gentamicin. Ann Burns Fire Disasters 2006; 19(3):140\u2013143","journal-title":"Ann Burns Fire Disasters"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-7-171"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.WON.0000264833.11108.35"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12262-012-0682-6"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0326871"}],"container-title":["Journal of Wound Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/jowc.2023.0159","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T11:51:25Z","timestamp":1779018685000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/jowc.2023.0159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,1]]},"references-count":29,"journal-issue":{"issue":"Sup5a","published-print":{"date-parts":[[2026,5,1]]}},"alternative-id":["10.12968\/jowc.2023.0159"],"URL":"https:\/\/doi.org\/10.12968\/jowc.2023.0159","relation":{},"ISSN":["0969-0700","2052-2916"],"issn-type":[{"value":"0969-0700","type":"print"},{"value":"2052-2916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,1]]}}}