{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:32:51Z","timestamp":1791977571450,"version":"4.4.0"},"reference-count":11,"publisher":"Mark Allen Group","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2025,5,2]]},"abstract":"<jats:p>Vitamin D is thought to be safe due to its wide therapeutic index and concentrations are rarely raised to toxic levels in the blood. However, excessive vitamin D supplementation can lead to hypervitaminosis D, causing hypercalcaemia and hyperphosphataemia. Due to its lipid solubility, vitamin D can be stored in adipose tissue, leading to persistent hypercalcaemia, even after supplementation has been discontinued. This case reports an 81-year-old female patient who developed hypervitaminosis D after taking excessive vitamin D supplementation for 30 years. The patient presented with complex bilateral leg wounds and tissue calcification. This case highlights the importance of monitoring vitamin D supplementation and the risks associated with hypervitaminosis D, including soft tissue calcification.<\/jats:p>","DOI":"10.12968\/jowc.2023.0177","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T08:57:06Z","timestamp":1747126626000},"page":"368-371","source":"Crossref","is-referenced-by-count":4,"title":["Hypervitaminosis D and hard-to-heal wounds: a case report"],"prefix":"10.12968","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-6437-8845","authenticated-orcid":false,"given":"Thomas Steve","family":"Jessop","sequence":"first","affiliation":[{"name":"MBChB Student, Division of Plastic Reconstructive Surgery, University of Stellenbosch, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9944-2033","authenticated-orcid":false,"given":"Nicolas","family":"Kairinos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5130","reference":[{"issue":"6","key":"B1","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1016\/j.clnu.2016.02.017","volume":"35","author":"P\u00e9rez-Barrios C","year":"2016","journal-title":"Clin Nutr"},{"issue":"4","key":"B2","doi-asserted-by":"crossref","first-page":"311","DOI":"10.7861\/clinmedicine.18-4-311","volume":"18","author":"Ellis S","year":"2018","journal-title":"Clin Med (Northfield Ill)"},{"key":"B3","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jsbmb.2017.07.006","volume":"180","author":"Razzaque MS","year":"2018","journal-title":"J Steroid Biochem Mol Biol"},{"issue":"9","key":"B4","volume":"15","author":"Costa E","year":"2023","journal-title":"Cureus"},{"issue":"4","key":"B5","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.4103\/jfmpc.jfmpc_1525_21","volume":"11","author":"Rathod SG","year":"2022","journal-title":"J Family Med Prim Care"},{"issue":"2","key":"B7","doi-asserted-by":"crossref","first-page":"166","DOI":"10.3945\/an.111.001628","volume":"3","author":"Theuwissen E","year":"2012","journal-title":"Adv Nutr"},{"issue":"2","key":"B9","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1097\/PRS.0b013e3181956551","volume":"123","author":"Kairinos N","year":"2009","journal-title":"Plast Reconstr Surg"},{"key":"B10","first-page":"103227","volume":"73","author":"Muneer S","year":"2022","journal-title":"Ann Med Surg (Lond)"},{"issue":"6","key":"B11","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/j.semarthrit.2005.01.016","volume":"34","author":"Boulman N","year":"2005","journal-title":"Semin Arthritis Rheum"},{"issue":"5","key":"B12","doi-asserted-by":"crossref","first-page":"652","DOI":"10.3390\/nu10050652","volume":"10","author":"Wang J","year":"2018","journal-title":"Nutrients"},{"issue":"6","key":"B13","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.mam.2008.04.002","volume":"29","author":"Zittermann A","year":"2008","journal-title":"Mol Aspects Med"}],"container-title":["Journal of Wound Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/jowc.2023.0177","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T08:57:23Z","timestamp":1747126643000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/jowc.2023.0177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,2]]},"references-count":11,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5,2]]}},"alternative-id":["10.12968\/jowc.2023.0177"],"URL":"https:\/\/doi.org\/10.12968\/jowc.2023.0177","relation":{},"ISSN":["0969-0700","2052-2916"],"issn-type":[{"value":"0969-0700","type":"print"},{"value":"2052-2916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,2]]}}}