{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T17:50:05Z","timestamp":1781977805945,"version":"3.54.5"},"reference-count":35,"publisher":"Mark Allen Group","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2026,6,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>\n                      It is important to evaluate limb blood flow during the perioperative period to salvage affected limbs in patients with chronic limb-threatening ischaemia (CLTI). However, it is difficult to evaluate limb blood flow during endovascular treatment (EVT). This study aimed to investigate the usefulness of regional tissue oxygen saturation (rSO\n                      <jats:sub>2<\/jats:sub>\n                      ) values measured by near-infrared spectroscopy (NIRS) techniques during EVT to predict the wound healing prognosis in patients with CLTI.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>\n                      Patients with CLTI who successfully underwent EVT between April 2018 and March 2022 were included. Patients who had infections or failed EVT were excluded. The rSO\n                      <jats:sub>2<\/jats:sub>\n                      value was measured in the affected limb using the NIRS device (TOE-20, Astem Co., Ltd., Japan) during EVT. At one year after EVT, the patients were divided into two groups: healing and non-healing. Intraprocedural rSO\n                      <jats:sub>2<\/jats:sub>\n                      values were retrospectively analysed to determine the cut-off value for wound healing using receiver operating characteristic (ROC) curve analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 34 patients (healing group: 15; non-healing group: 19) were included in this study. Intraprocedural rSO\n                      <jats:sub>2<\/jats:sub>\n                      values were significantly higher in the healing group than in the non-healing group (51.1\u00b13.4% versus 44.4\u00b15.0%, respectively; p&lt;0.001). ROC curve analysis revealed that the optimal cut-off intraprocedural rSO\n                      <jats:sub>2<\/jats:sub>\n                      value for wound healing within one year was 47.0% (sensitivity: 86.7%, specificity: 73.7%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      The results of this study showed that intraprocedural rSO\n                      <jats:sub>2<\/jats:sub>\n                      values during EVT may be useful in the prediction of postoperative wound healing in patients with CLTI.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.12968\/jowc.2023.0211","type":"journal-article","created":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T17:11:32Z","timestamp":1780679492000},"page":"510-518","source":"Crossref","is-referenced-by-count":0,"title":["Regional tissue oxygen saturation as an indicator of wound healing during endovascular treatment for chronic limb-threatening ischaemia"],"prefix":"10.12968","volume":"35","author":[{"given":"Hajime","family":"Tsuyuki","sequence":"first","affiliation":[{"name":"Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan"},{"name":"Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2601-0226","authenticated-orcid":false,"given":"Masaki","family":"Sano","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan"},{"name":"Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazunori","family":"Inuzuka","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan"},{"name":"Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuto","family":"Katahashi","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan"},{"name":"Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takafumi","family":"Kayama","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Hamamatsu Medical Center, Hamamatsu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Yamanaka","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan"},{"name":"Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Endo","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan"},{"name":"Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nozomu","family":"Ishikawa","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan"},{"name":"Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiyuki","family":"Ojima","sequence":"additional","affiliation":[{"name":"Department of Community Health and Preventive Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroya","family":"Takeuchi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Unno","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Hamamatsu Medical Center, Hamamatsu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5130","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx095"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2006.09.024"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2014.12.009"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.19.21967"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1253\/circj.72.605"},{"issue":"6","key":"e_1_3_2_6_2","first-page":"479","article-title":"Transcutaneous oxygen pressure measurements in diabetic and non-diabetic patients clinically suspected of severe limb ischemia: a matched paired retrospective analysis","volume":"28","author":"Biotteau E","year":"2009","unstructured":"Biotteau E, Mahe G, Rousseau P et al. Transcutaneous oxygen pressure measurements in diabetic and non-diabetic patients clinically suspected of severe limb ischemia: a matched paired retrospective analysis. Int Angiol 2009; 28(6):479\u2013483","journal-title":"Int Angiol"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X14565372"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(97)70062-4"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.3400\/avd.oa.20-00132"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2016.07.020"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.21.4.040502"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mvr.2015.11.004"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-004-2833-2"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2005.10.025"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1006\/jsre.1996.0059"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(05)80014-X"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2007.10.045"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.3400\/avd.oa.18-00117"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2019.05.006"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0007-1226(87)90185-8"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvscit.2021.07.001"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-21-1041"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000119574.27772.FD"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2015.07.005"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2012.07.017"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2015.03.034"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29688"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1024\/0301-1526.29.3.191"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00253861"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.3892\/br.2018.1064"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20140571"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2021.06.009"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2263011728"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1097\/PHM.0b013e3182876a06"},{"issue":"4","key":"e_1_3_2_35_2","first-page":"95","article-title":"Importance of skin perfusion pressure in treatment of critical limb ischemia","volume":"20","author":"Tsuji Y","year":"2008","unstructured":"Tsuji Y, Hiroto T, Kitano I et al. Importance of skin perfusion pressure in treatment of critical limb ischemia. Wounds 2008; 20(4):95\u2013100","journal-title":"Wounds"}],"container-title":["Journal of Wound Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/jowc.2023.0211","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T17:11:48Z","timestamp":1781975508000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/jowc.2023.0211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,2]]},"references-count":35,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6,2]]}},"alternative-id":["10.12968\/jowc.2023.0211"],"URL":"https:\/\/doi.org\/10.12968\/jowc.2023.0211","relation":{},"ISSN":["0969-0700","2052-2916"],"issn-type":[{"value":"0969-0700","type":"print"},{"value":"2052-2916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,2]]}}}