{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T03:25:10Z","timestamp":1758079510714,"version":"3.44.0"},"reference-count":9,"publisher":"Mark Allen Group","issue":"Sup9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2024,9,1]]},"abstract":"<jats:p> Catatrophic antiphospholipid syndrome (CAPS), a rare variant of antiphospholipid syndrome (APS), is associated with rapid multiorgan failure. While APS is associated with single medium-to-large blood vessel occlusions, CAPS is most often associated with several, concurrent vascular occlusions of small vessels, commonly of the kidneys, heart, skin and brain. We present a case of a 21-year-old female patient with a history of immune thrombocytopenia purpura and APS, who eventually developed concurrent cerebral venous sinus thrombosis, diffuse alveolar haemorrhage, renal thrombotic microangiopathy, and a necrotic, vasculitic wound on her forearm. Despite hospitalisation and treatment, her condition worsened and the patient eventually died after succumbing to suspected CAPS. <\/jats:p>","DOI":"10.12968\/jowc.2023.0285","type":"journal-article","created":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T16:00:57Z","timestamp":1758038457000},"page":"S23-S26","source":"Crossref","is-referenced-by-count":0,"title":["Catastrophic antiphospholipid syndrome: a case report and literature review"],"prefix":"10.12968","volume":"33","author":[{"given":"Jun","family":"Kyoung","sequence":"first","affiliation":[{"name":"University of Toledo, College of Medicine and Life Sciences, Toledo, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren","family":"Workman","sequence":"additional","affiliation":[{"name":"University of Toledo, College of Medicine and Life Sciences, Toledo, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taylor","family":"Spurgeon-Hess","sequence":"additional","affiliation":[{"name":"University of Toledo, College of Medicine and Life Sciences, Toledo, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirollos S","family":"Tadrousse","sequence":"additional","affiliation":[{"name":"University of Toledo, College of Medicine and Life Sciences, Toledo, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Drew","family":"Oostra","sequence":"additional","affiliation":[{"name":"Jobst Vascular Institute, ProMedica Health Network, Hematology Oncology, Toledo, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Simman","sequence":"additional","affiliation":[{"name":"Jobst Vascular Institute, ProMedica Health Network, Wound Care Program, Toledo, Ohio, USA"},{"name":"University of Toledo, College of Medicine and Life Science, Department of Surgery, Toledo, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5130","reference":[{"issue":"6","key":"B1","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1136\/annrheumdis-2013-204838","volume":"74","author":"Cervera R","year":"2015","journal-title":"Ann Rheum Dis"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1191\/0961203303lu394oa"},{"issue":"12","key":"B3","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1016\/j.autrev.2016.09.010","volume":"15","author":"Rodr\u00edguez-Pint\u00f3 I","year":"2016","journal-title":"Autoimmun Rev"},{"issue":"1","key":"B4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaut.2008.10.003","volume":"32","author":"Ortega-Hernandez OD","year":"2009","journal-title":"J Autoimmun"},{"issue":"5","key":"B5","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/s11926-003-0031-7","volume":"5","author":"Asherson RA","year":"2003","journal-title":"Curr Rheumatol Rep"},{"issue":"2","key":"B6","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.autrev.2006.06.005","volume":"6","author":"Asherson RA","year":"2006","journal-title":"Autoimmun Rev"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000721136.35507.aa"},{"issue":"12","key":"B8","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1177\/0961203320950461","volume":"29","author":"Cohen H","year":"2020","journal-title":"Lupus"},{"key":"B9","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.thromres.2020.10.010","volume":"198","author":"Sayar Z","year":"2021","journal-title":"Thromb Res"}],"container-title":["Journal of Wound Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/jowc.2023.0285","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T16:00:58Z","timestamp":1758038458000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/jowc.2023.0285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,1]]},"references-count":9,"journal-issue":{"issue":"Sup9","published-print":{"date-parts":[[2024,9,1]]}},"alternative-id":["10.12968\/jowc.2023.0285"],"URL":"https:\/\/doi.org\/10.12968\/jowc.2023.0285","relation":{},"ISSN":["0969-0700","2052-2916"],"issn-type":[{"value":"0969-0700","type":"print"},{"value":"2052-2916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,1]]}}}