{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T16:09:14Z","timestamp":1764950954750,"version":"3.46.0"},"reference-count":34,"publisher":"Mark Allen Group","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2025,12,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To evaluate the incremental cost-effectiveness and cost-utility ratios (ICER; ICUR) of a single-layer high compression bandage (SLHCB) compared with Unna's boot (UB) from the perspective of the Brazilian healthcare system, with a time horizon of 26 weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>A health economic evaluation of data from a prospective, randomised, open blinded endpoint study was conducted in 22 primary healthcare services in Porto Alegre city, Brazil, with patients with venous leg ulcers (VLUs) who were randomly allocated to receive SLHCB or UB. Participants were followed until VLU healing or up to 26 weeks. Nurses performed dressings weekly and blinded examiners measured the VLU size by planimetry at baseline and every two weeks. The Short Form-6 Dimensions questionnaire was applied at baseline and on the last day of follow-up to measure quality-adjusted life years (QALYs). The ICER and ICUR were estimated, and probabilistic sensitivity analyses performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 61 participants were enrolled in the trial, corresponding to 110 VLUs. SLHCB incurred an average expenditure of R$1118.74 (I$442.19) per VLU, while UB incurred R$1078.74 (I$426.38) per VLU. SLHCB exhibited a mean VLU reduction of 64.82% compared with 27.56% for UB. The mean QALY for SLHCB was 0.187 and 0.164 for UB. The ICER was 1.07 (0.42) per percentage point of VLUs healed and the ICUR was 1739.13 (687.40) per QALY gained.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In this study, SLHCB was cost-effective when compared with UB. These findings may prompt decision-makers to weigh the prospect of allocating an additional R$1.07 (I$0.42) for each percentage point reduction in VLU area or R$1739.13 (I$687.40) per QALY gained. This financial consideration holds significant implications for guiding resource allocation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.12968\/jowc.2024.0015","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T16:04:22Z","timestamp":1764950662000},"page":"982-990","source":"Crossref","is-referenced-by-count":0,"title":["Cost-effectiveness of a single-layer high compression bandage versus Unna's boot for venous leg ulcer treatment: the VENOS trial"],"prefix":"10.12968","volume":"34","author":[{"given":"Ana Cl\u00e1udia","family":"Fuhrmann","sequence":"first","affiliation":[{"name":"Nursing School, Universidade Federal of Rio Grande do Sul, Porto Alegre\/RS, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda Peixoto","family":"Cordova","sequence":"additional","affiliation":[{"name":"Hospital de Clinicas de Porto Alegre, Porto Alegre\/RS, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diani Oliveira","family":"Machado","sequence":"additional","affiliation":[{"name":"Grupo Hospitalar Concei\u00e7\u00e3o, Porto Alegre\/RS, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duane","family":"Mocellin","sequence":"additional","affiliation":[{"name":"Hospital Moinhos de Vento, Porto Alegre\/RS, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey A","family":"Johnson","sequence":"additional","affiliation":[{"name":"School of Public Health, University of Alberta, Edmonton\/AB, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisiane Manganelli Girardi","family":"Paskulin","sequence":"additional","affiliation":[{"name":"Nursing School, Universidade Federal of Rio Grande do Sul, Porto Alegre\/RS, Brazil"},{"name":"Hospital de Clinicas de Porto Alegre, Porto Alegre\/RS, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5130","reference":[{"issue":"5","key":"B1","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1002\/bjs.11082","volume":"106","author":"Epstein DM","year":"2019","journal-title":"Br J Surg"},{"issue":"3","key":"B2","doi-asserted-by":"crossref","first-page":"181","DOI":"10.23736\/S0392-9590.18.03999-8","volume":"37","author":"Nicolaides A","year":"2018","journal-title":"Int Angiol"},{"issue":"5","key":"B3","first-page":"298","volume":"100","author":"Bonkemeyer Millan S","year":"2019","journal-title":"Am Fam Physician"},{"key":"B4","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s12262-021-03064-x","volume":"85","author":"Jindal R","year":"2023","journal-title":"Indian J Surg"},{"issue":"1","key":"B5","doi-asserted-by":"crossref","first-page":"29","DOI":"10.3390\/jcm10010029","volume":"10","author":"Raffetto JD","year":"2020","journal-title":"J Clin Med"},{"issue":"22","key":"B6","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1056\/NEJMoa1801214","volume":"378","author":"Gohel MS","year":"2018","journal-title":"N Engl J Med"},{"issue":"2","key":"B7","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1111\/iwj.13891","volume":"20","author":"Patton D","year":"2023","journal-title":"Int Wound J"},{"issue":"7","key":"B8","first-page":"CD013397","volume":"7","author":"Shi C","year":"2021","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"B9","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.jvsv.2021.06.010","volume":"10","author":"Shaydakov ME","year":"2022","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"issue":"2","key":"B10","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.jtv.2019.02.004","volume":"28","author":"Oates A","year":"2019","journal-title":"J Tissue Viability"},{"issue":"1","key":"B11","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1177\/1358863X211028298","volume":"27","author":"Kolluri R","year":"2022","journal-title":"Vasc Med"},{"key":"B12","unstructured":"Bjork R. The long and short of it: understanding compression bandaging. Wound Care Advisor 2013; 2(6). https:\/\/woundcareadvisor.com\/best-practices-vol2-no6\/"},{"issue":"3","key":"B13","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1111\/wrr.12903","volume":"29","author":"Paranhos T","year":"2021","journal-title":"Wound Repair Regen"},{"issue":"1","key":"B14","doi-asserted-by":"crossref","first-page":"e056790","DOI":"10.1136\/bmjopen-2021-056790","volume":"12","author":"Urwin S","year":"2022","journal-title":"BMJ Open"},{"issue":"1","key":"B15","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/wrr.12683","volume":"27","author":"Olsson M","year":"2019","journal-title":"Wound Repair Regen"},{"issue":"14","key":"B16","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1001\/jama.2019.1265","volume":"321","author":"Sanders GD","year":"2019","journal-title":"JAMA"},{"issue":"4","key":"B17","doi-asserted-by":"crossref","first-page":"216","DOI":"10.33235\/wpr.30.4.216-222","volume":"30","author":"Cordova FP","year":"2022","journal-title":"Wound Practice Res"},{"key":"B18","unstructured":"Ministry of Health [Brazil]. [Methodological guidelines: economic evaluation studies of health technologies] [in Portuguese]. 2nd ed. Bras\u00edlia-DF. 2014. https:\/\/tinyurl.com\/yupxshkk (accessed 5 November 2025)"},{"key":"B19","doi-asserted-by":"crossref","first-page":"e067975","DOI":"10.1136\/bmj-2021-067975","volume":"376","author":"Husereau D","year":"2022","journal-title":"BMJ"},{"issue":"7","key":"B20","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1177\/0268355520988226","volume":"36","author":"Stather P","year":"2021","journal-title":"Phlebology"},{"issue":"7","key":"B21","doi-asserted-by":"crossref","first-page":"300","DOI":"10.12968\/jowc.2015.24.7.300","volume":"24","author":"Guest JF","year":"2015","journal-title":"J Wound Care"},{"issue":"5","key":"B22","doi-asserted-by":"crossref","first-page":"244","DOI":"10.12968\/jowc.2017.26.5.244","volume":"26","author":"Guest JF","year":"2017","journal-title":"J Wound Care"},{"issue":"3","key":"B23","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1046\/j.1524-475X.2003.11303.x","volume":"11","author":"Moffatt CJ","year":"2003","journal-title":"Wound Repair Regen"},{"key":"B24","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.vhri.2018.02.003","volume":"17","author":"Campolina AG","year":"2018","journal-title":"Value Health Reg Issues"},{"key":"B25","doi-asserted-by":"crossref","first-page":"S108","DOI":"10.1016\/j.jval.2011.05.012","volume":"14","author":"Cruz LN","year":"2011","journal-title":"Value Health"},{"key":"B26","unstructured":"Porto Alegre City Hall. Bidding and Contracts Department. [Price registry for goods\/materials] [in Portuguese]. Porto Alegre, Brazil. https:\/\/tinyurl.com\/5aahpe44 (accessed 11 November 2025)"},{"key":"B27","unstructured":"Porto Alegre City Hall. [Composition of the remuneration of career civil servants of the direct administration, autonomous agencies, and foundation] [In Portuguese]. https:\/\/tinyurl.com\/2sdzeye5 (accessed 5 November 2025)"},{"key":"B28","unstructured":"Organization for Economic Cooperation and Development. Purchasing power parities (PPP). 2022. https:\/\/tinyurl.com\/42kpawm9 (accessed 15 Octover 2025)"},{"key":"B29","unstructured":"Ministry of Health [Brazil]. [The use of cost-effectiveness thresholds in health decisions: recommendations from the National Committee for Health Technology Incorporation in SUS] [in Portuguese]. 2022. https:\/\/tinyurl.com\/3jm5t3nn (accessed 5 November 2025)"},{"issue":"2","key":"B30","first-page":"155","volume":"12","author":"Ribeiro BT","year":"2020","journal-title":"J Bras Econ Sa\u00fade."},{"issue":"1","key":"B31","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1186\/s13643-020-01536-x","volume":"9","author":"Shields GE","year":"2020","journal-title":"Syst Rev"},{"issue":"4","key":"B32","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1590\/0104-1169.0373.2590","volume":"23","author":"Abreu AM","year":"2015","journal-title":"Rev Lat Am Enfermagem"},{"key":"B33","first-page":"e3839","volume":"31","author":"Sodr\u00e9 SL","year":"2023","journal-title":"Rev Lat Am Enfermagem"},{"key":"B34","unstructured":"Weir D, Davies P. The impact of venous leg ulcers on a patient's quality of life: considerations for dressing selection. Wounds International. 2023. 14(1). https:\/\/tinyurl.com\/4xxa66x7 (accessed 15 October 2025)"}],"container-title":["Journal of Wound Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/pdf\/10.12968\/jowc.2024.0015","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T16:05:17Z","timestamp":1764950717000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.magonlinelibrary.com\/doi\/10.12968\/jowc.2024.0015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,2]]},"references-count":34,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12,2]]}},"alternative-id":["10.12968\/jowc.2024.0015"],"URL":"https:\/\/doi.org\/10.12968\/jowc.2024.0015","relation":{},"ISSN":["0969-0700","2052-2916"],"issn-type":[{"value":"0969-0700","type":"print"},{"value":"2052-2916","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,2]]}}}