{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T20:22:27Z","timestamp":1785529347912,"version":"3.56.0"},"reference-count":15,"publisher":"Mark Allen Group","issue":"Sup9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Wound Care"],"published-print":{"date-parts":[[2024,9,1]]},"abstract":"<jats:sec><jats:title>Objective:<\/jats:title><jats:p> This case series examines the use of a multimodal wound matrix (MWM) trialled in a selection of clinical practice settings and on a variety of hard-to-heal wounds. The objective was to evaluate the effects of MWM and its performance in managing such wounds, regardless of clinical setting and ulcer type. <\/jats:p><\/jats:sec><jats:sec><jats:title>Method:<\/jats:title><jats:p> Treatment of the MWM was conducted by independent wound care practitioners on wounds that were of &gt;4 weeks duration. Treatment was once a week. Assessment was taken after four weeks and at week 12 of the study to assess percentage area reduction (PAR) compared to baseline measurements taken at the first treatment visit. Complete (100%) re-epithelialisation was also recorded. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> A total of 63 wounds were treated with MWM, and ulcer types were grouped as: diabetic foot ulcers (n=21); venous leg ulcers (n=18); pressure injuries (n=10); and others (n=14). Of the wounds, 78% had 100% re-epithelialisation, with an average PAR of 57% at four weeks and 86% at 12 weeks. The average time to resolution for those wounds that closed was 7.9 weeks. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> Results from this series of independent case studies support the application of MWM to potentially benefit healing in hard-to-heal wounds of different aetiologies of any duration and in a variety of clinical settings. <\/jats:p><\/jats:sec>","DOI":"10.12968\/jowc.2024.0135","type":"journal-article","created":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T17:38:13Z","timestamp":1726508293000},"page":"S27-S35","source":"Crossref","is-referenced-by-count":3,"title":["The use of a multimodal wound matrix to treat a variety of hard-to-heal wounds: a case series surveillance"],"prefix":"10.12968","volume":"33","author":[{"given":"David","family":"Swain","sequence":"first","affiliation":[{"name":"First Coast Cardiovascular Institute, Jacksonville, FL, US"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Windy","family":"Cole","sequence":"additional","affiliation":[{"name":"Kent State University College of Podiatric Medicine, Kent, OH, US"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Barrett","sequence":"additional","affiliation":[{"name":"Wound Care Specialist, Downingtown, PA, US"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"Black","sequence":"additional","affiliation":[{"name":"Sylvania Podiatry, Sylvania, OH, US"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Hudson","sequence":"additional","affiliation":[{"name":"United Wound Healing, Coos Bay, OR, US"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Lacqua","sequence":"additional","affiliation":[{"name":"Richmond University Medical Centre, Staten Island, NY, 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