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Tomizawa,                D,              Miyamura, T,                Koh, K,                Ishii,            E. Acute            lymphoblastic leukemia in infants: A quarter century of nationwide efforts in            Japan. Pediatr Int          2022;64: e14935.","DOI":"10.1111\/ped.14935"},{"key":"2","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1038\/sj.leu.2404903","volume":"21","year":"2007","unstructured":"2. Tomizawa,                D, Koh,                K, Sato,                T,              Kinukawa, N,                Morimoto,            A, Isoyama,                K, et al.            Outcome of risk-based therapy for infant acute lymphoblastic leukemia            with or without an MLL gene rearrangement, with emphasis on late effects: a final report            of two consecutive studies, MLL96 and MLL98, of the Japan Infant Leukemia Study            Group. Leukemia          2007;21: 2258\u201363.","journal-title":"Leukemia","ISSN":"https:\/\/id.crossref.org\/issn\/0887-6924","issn-type":"print"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Green,              DM, Nolan,                VG,              Goodman, PJ,                Whitton,            JA, Srivastava,                D,                Leisenring,              WM, et al.            The cyclophosphamide equivalent dose as an approach for quantifying            alkylating agent exposure: a report from the Childhood Cancer Survivor            Study. Pediatr Blood Cancer          2014;61: 53\u201367.","DOI":"10.1002\/pbc.24679"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Mostoufi-Moab,                S, Seidel,                K,                Leisenring,              WM,              Armstrong,            GT, Oeffinger,                KC,              Stovall, M,              et al. Endocrine abnormalities in aging            survivors of childhood cancer: a report from the childhood cancer survivor            study. J Clin Oncol          2016;34: 3240\u20137.","DOI":"10.1200\/JCO.2016.66.6545"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Green,              DM, Liu,                W, Kutteh,                WH, Ke,                RW,              Shelton, KC,                Sklar, CA,              et al. Cumulative alkylating agent exposure            and semen parameters in adult survivors of childhood cancer: a report from the St Jude            Lifetime Cohort Study. Lancet Oncol          2014;15: 1215\u201323.","DOI":"10.1016\/S1470-2045(14)70408-5"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Fujino,              H, Ishida,                H, Iguchi,                A, Onuma,                M, Kato,                K, Shimizu,                M, et al.            High rates of ovarian function preservation after hematopoietic cell            transplantation with melphalan-based reduced intensity conditioning for pediatric acute            leukemia: an analysis from the Japan Association of Childhood Leukemia Study            (JACLS). Int J Hematol          2019;109: 578\u201383.","DOI":"10.1007\/s12185-019-02627-9"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Kato,              N, Takimoto,                H, Sudo,                N. The cubic            functions for spline smoothed L, S and M values for BMI reference data of japanese            children. Clin Pediatr Endocrinol          2011;20: 47\u20139.","DOI":"10.1297\/cpe.20.47"},{"key":"8","unstructured":"8. The Japan Society for Hematopoietic Cell          Transplantation [homepage on internet]. Hematopoietic stem cell transplantation Guideline:            <i>GVHD<\/i>, 4th edn. 2018; 2-15[Cited 2021Nov25]. Available          from: https:\/\/www.jshct.com\/uploads\/files\/guideline\/01_02_gvhd_ver04.pdf."},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Tews,              D, Schulz,                A, Denzer,                C, von                Schnurbein, J,                Ceccarini,              G, Debatin,                KM, et al.            Lipodystrophy as a late effect after stem cell            transplantation. J Clin Med          2021;10: 1559.","DOI":"10.3390\/jcm10081559"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Tanaka,              T, Naiki,                Y,              Horikawa, R,                Satoh,            M. Adult height            prediction method for pubertal short children (Growth Potential II            Method). J Jpn Ass Hum Auxo          2009;15: 17\u201322(In            Japanese).","DOI":"10.1297\/cpe.17.9"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Shimazaki,                S,              Kazukawa, I,                Mori, K,                Kihara, M,                Minagawa,            M. Factors            predicting endocrine late effects in childhood cancer survivors from a Japanese            hospital. Endocr J          2020;67: 131\u201340.","DOI":"10.1507\/endocrj.EJ19-0228"},{"key":"12","unstructured":"12. The Japanese Society for Pediatric            Endocrinology, editor. A practical guide to the endocrine management of          childhood cancer patients, 1st ed., SHINDAN TO CHIRYO SHA, Inc, Tokyo, Japan,            2021; 66\u20139 (in Japanese)."},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Tonorezos,                ES, Hudson,                MM, Edgar,                AB, Kremer,                LC, Sklar,                CA,              Wallace, WH,              et al. Screening and management of adverse            endocrine outcomes in adult survivors of childhood and adolescent          cancer. Lancet Diabetes Endocrinol          2015;3: 545\u201355.","DOI":"10.1016\/S2213-8587(15)00038-8"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Miyoshi,              Y, Ohta,                H, Hashii,                Y,              Tokimasa, S,                Namba, N,                Mushiake,            S, et al.            Endocrinological analysis of 122 Japanese childhood cancer survivors in a            single hospital. Endocr J          2008;55: 1055\u201363.","DOI":"10.1507\/endocrj.K08E-075"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Patterson,                BC,                Wasilewski-Masker,              K, Ryerson,                AB,              Mertens, A,                Meacham,            L. Endocrine            health problems detected in 519 patients evaluated in a pediatric cancer survivor            program. J Clin Endocrinol Metab          2012;97: 810\u20138.","DOI":"10.1210\/jc.2011-2104"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Tomizawa,                D,              Miyamura, T,                Imamura, T,                Watanabe,            T, Moriya              Saito, A,                Ogawa, A,              et al. A risk-stratified therapy for            infants with acute lymphoblastic leukemia: a report from the JPLSG MLL-10            trial. Blood          2020;136: 1813\u201323.","DOI":"10.1182\/blood.2019004741"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Koh,              K, Kato,                M, Saito,                AM, Kada,                A,              Kawasaki, H,                Okamoto, Y,              et al. Phase II\/III study in children and            adolescents with newly diagnosed B-cell precursor acute lymphoblastic leukemia: protocol            for a nationwide multicenter trial in Japan. Jpn J Clin            Oncol          2018;48: 684\u201391.","DOI":"10.1093\/jjco\/hyy071"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Bizzarri,                C, Pinto,                RM,              Ciccone, S,                Brescia,            LP, Locatelli,                F, Cappa,                M. Early and            progressive insulin resistance in young, non-obese cancer survivors treated with            hematopoietic stem cell transplantation. Pediatr Blood            Cancer          2015;62: 1650\u20135.","DOI":"10.1002\/pbc.25603"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Meacham,                LR, Sklar,                CA, Li,                S, Liu,                Q, Gimpel,                N, Yasui,                Y, et al.            Diabetes mellitus in long-term survivors of childhood cancer. Increased            risk associated with radiation therapy: a report for the childhood cancer survivor            study. Arch Intern Med          2009;169: 1381\u20138.","DOI":"10.1001\/archinternmed.2009.209"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Friedman,                DN,                Tonorezos,              ES, Cohen,                P. Diabetes            and metabolic syndrome in survivors of childhood cancer. Horm            Res Paediatr          2019;91: 118\u201327.","DOI":"10.1159\/000495698"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Adachi,              M, Oto,                Y, Muroya,                K,              Hanakawa, J,                Asakura, Y,                Goto,            H. Partial            lipodystrophy in patients who have undergone hematopoietic stem cell transplantation            during childhood: an institutional cross-sectional survey. Clin            Pediatr Endocrinol          2017;26: 99\u2013108.","DOI":"10.1297\/cpe.26.99"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Adachi,              M, Asakura,                Y, Muroya,                K, Goto,                H,              Kigasawa,            H. Abnormal            adipose tissue distribution with unfavorable metabolic profile in five children            following hematopoietic stem cell transplantation: a new etiology for acquired partial            lipodystrophy. 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