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BMC Public Health          2014;14: 25.","DOI":"10.1186\/1471-2458-14-25"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Saito,              M,                Yamamoto-Hanada,              K, Pak,                K, Ayabe,                T, Mezawa,                H,                Ishitsuka,              K, et al.            Japan Environment and Children\u2019s Study (JECS) Group.            Having small-for-gestational-age infants was associated with maternal            allergic features in the JECS birth cohort. Allergy          2018;73: 1908\u201311.","DOI":"10.1111\/all.13490"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Yamamoto-Hanada,                K,                Ishitsuka,              K, Pak,                K, Saito,                M, Ayabe,                T, Mezawa,                H, et al.            Japan Environment and Children\u2019s Study (JECS) Group.            Allergy and mental health among pregnant women in the Japan Environment            and Children\u2019s Study. J Allergy Clin Immunol Pract          2018;6: 1421\u20131424.e2.","DOI":"10.1016\/j.jaip.2017.12.006"},{"key":"8","unstructured":"8. Japan Environment and Children\u2019s            Study (JECS) Sub-Cohort Study Protocol. Available from https:\/\/www.env.go.jp\/chemi\/ceh\/en\/about\/advanced\/material\/jecs-sub-cohort_study_protocol_101-en.pdf."},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Sekiyama,                M,              Yamazaki, S,                Michikawa,              T, Nakayama,                SF, Nitta,                H,                Taniguchi,              Y, et al.            Japan Environment and Children\u2019s Study Group.            Study design and participants\u2019 profile in the sub-cohort study in the            Japan Environment and Children\u2019s Study (JECS). J            Epidemiol          2022;32: 228\u201336.","DOI":"10.2188\/jea.JE20200448"},{"key":"10","unstructured":"10. Japan Environment and Children\u2019s            Study (JECS) Study Protocol. Available from https:\/\/www.env.go.jp\/chemi\/ceh\/en\/about\/advanced\/material\/jecs-study_protocol_14_en.pdf."},{"key":"11","unstructured":"11. Sorcini,              M, Fazzini,                C,              Olivieri, A,                Grandolfo,              ME, Medda,                E, Stazi,                MA, et al.            The National Registry. Neonatal screening in            congenital hypothyroidism in Italy. Ann Ist Super            Sanita          1994;30: 275\u201387."},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Medda,              E, Olivieri,                A, Stazi,                MA,                Grandolfo,              ME, Fazzini,                C, Baserga,                M, et al.            Risk factors for congenital hypothyroidism: results of a population            case-control study (1997-2003). Eur J Endocrinol          2005;153: 765\u201373.","DOI":"10.1530\/eje.1.02048"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Oakley,              GA, Muir,                T, Ray,                M,              Girdwood, RW,                Kennedy, R,                Donaldson,              MD. Increased            incidence of congenital malformations in children with transient thyroid-stimulating            hormone elevation on neonatal screening. J Pediatr          1998;132: 726\u201330.","DOI":"10.1016\/S0022-3476(98)70369-5"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Chen,              J, Lin,                S, Zeng,                G, Wang,                W, Lin,                Z, Xu,                C, et al.            Epidemiologic characteristics and risk factors for congenital            hypothyroidism from 2009 to 2018 in Xiamen, China. Endocr            Pract          2020;26: 585\u201394.","DOI":"10.4158\/EP-2019-0491"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Chen,              CY, Lee,                KT, Lee,                CT, Lai,                WT, Huang,                YB.            Epidemiology and clinical characteristics of congenital hypothyroidism in            an Asian population: a nationwide population-based study. J            Epidemiol          2013;23: 85\u201394.","DOI":"10.2188\/jea.JE20120113"},{"key":"16","doi-asserted-by":"publisher","unstructured":"16. Nishiyama,                S, Mikeda,                T, Okada,                T,              Nakamura, K,                Kotani, T,                Hishinuma,              A. Transient            hypothyroidism or persistent hyperthyrotropinemia in neonates born to mothers with            excessive iodine intake. Thyroid          2004;14: 1077\u201383.","DOI":"10.1089\/thy.2004.14.1077"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Hall,              SK,                Hutchesson,              AC, Kirk,                JM.            Congenital hypothyroidism, seasonality and consanguinity in the West            Midlands, England. Acta Paediatr          1999;88: 212\u20135.","DOI":"10.1111\/j.1651-2227.1999.tb01084.x"},{"key":"18","doi-asserted-by":"publisher","unstructured":"18. Gu,                YH, Kato,                T, Harada,                S, Inomata,                H, Saito,                T, Aoki,                K.            Seasonality in the incidence of congenital hypothyroidism in Japan:            gender-specific patterns and correlation with temperature.            Thyroid          2007;17: 869\u201374.","DOI":"10.1089\/thy.2006.0317"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Gu,                YH, Harada,                S, Kato,                T, Inomata,                H, Aoki,                K,              Hirahara,            F. Increased            incidence of extrathyroidal congenital malformations in Japanese patients with            congenital hypothyroidism and their relationship with Down syndrome and other            factors. Thyroid          2009;19: 869\u201379.","DOI":"10.1089\/thy.2008.0405"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Tuli,              G, Munarin,                J,              Tessaris, D,                Matarazzo,              P, Einaudi,                S, de                Sanctis, L.            Incidence of primary congenital hypothyroidism and relationship between            diagnostic categories and associated malformations.            Endocrine          2021;71: 122\u20139.","DOI":"10.1007\/s12020-020-02370-w"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Wu,                MH, Chen,                HC, Lu,                CW, Wang,                JK, Huang,                SC, Huang,                SK.            Prevalence of congenital heart disease at live birth in            Taiwan. J Pediatr          2010;156: 782\u20135.","DOI":"10.1016\/j.jpeds.2009.11.062"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Sadowski,                SL.            Congenital cardiac disease in the newborn infant: past, present, and            future. Crit Care Nurs Clin North Am          2009;21: 37\u201348,            vivi.","DOI":"10.1016\/j.ccell.2008.10.001"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Korevaar,                TI, Chaker,                L, Jaddoe,                VW, Visser,                TJ, Medici,                M, Peeters,                RP. 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