{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T16:31:38Z","timestamp":1781109098965,"version":"3.54.1"},"reference-count":38,"publisher":"Japanese Society for Pediatric Endocrinology","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pediatr Endocrinol"],"published-print":{"date-parts":[[2025]]},"DOI":"10.1297\/cpe.2024-0040","type":"journal-article","created":{"date-parts":[[2024,10,26]],"date-time":"2024-10-26T18:14:46Z","timestamp":1729966486000},"page":"27-35","source":"Crossref","is-referenced-by-count":1,"title":["Multifaceted delineation of atrophic thyroiditis among pediatric population:          An extensive literature survey"],"prefix":"10.1297","volume":"34","author":[{"given":"Sakura","family":"Motegi","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Showa University School of Medicine, Tokyo,              Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Adachi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Showa University School of Medicine, Tokyo,              Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiko","family":"Nagahara","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Showa University School of Medicine, Tokyo,              Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuyuki","family":"Ishida","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Showa University School of Medicine, Tokyo,              Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayako","family":"Ochi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Showa University School of Medicine, Tokyo,              Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsumi","family":"Mizuno","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Showa University School of Medicine, Tokyo,              Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"125","reference":[{"key":"1","unstructured":"1. Brent,              GA, Weetman,                AP. Hypothyroidism and          thyroiditis. In: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, editors. Williams          Textbook of Endocrinology 14<sup>th<\/sup> edition. Amsterdam: Elsevier Health Sciences          Division; 2019. p.404-432."},{"key":"2","unstructured":"2. van                Vliet, G,                Delado\u00eby,            J. Hypothyroidism in infants,          children, and adolescents: acquired hypothyroidism. In: Braverman LE, Cooper DS, editors.          Werner &amp; Ingbar\u2019s The Thyroid: A Fundamental and Clinical Text 10<sup>th<\/sup>          edition. Philadelphia: Lippincott Williams &amp; Wilkins; 2012.          p.797-802."},{"key":"3","unstructured":"3. Huang,              SA. Hypothyroidism. In:          Lifshitz F editor. Pediatric Endocrinology: Growth, Adrenal, Sexual, Thyroid, Calcium, and          Fluid Balance Disorders 5<sup>th<\/sup> edition Volume 2. Boca Raton: CRC Press;            2007. p.405-14."},{"key":"4","doi-asserted-by":"publisher","unstructured":"4. Roberts,                CG,                Ladenson,              PW.            Hypothyroidism. Lancet          2004;363: 793\u2013803.","DOI":"10.1016\/S0140-6736(04)15696-1"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Gopalakrishnan,                S, Marwaha,                RK. Juvenile            autoimmune thyroiditis. J Pediatr Endocrinol Metab          2007;20: 961\u201370.","DOI":"10.1515\/JPEM.2007.20.9.961"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Carl\u00e9,              A, Pedersen,                IB,              Knudsen, N,                Perrild, H,                Ovesen, L,                J\u00f8rgensen,              T, et al.            Thyroid volume in hypothyroidism due to autoimmune disease follows a            unimodal distribution: evidence against primary thyroid atrophy and autoimmune            thyroiditis being distinct diseases. J Clin Endocrinol            Metab          2009;94: 833\u20139.","DOI":"10.1210\/jc.2008-1370"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Matsuura,                N, Konishi,                J, Yuri,                K, Harada,                S, Fujieda,                K, Nohara,                Y, et al.            Comparison of atrophic and goitrous auto-immune thyroiditis in children:            clinical, laboratory and TSH-receptor antibody studies. Eur J            Pediatr          1990;149: 529\u201333.","DOI":"10.1007\/BF01957685"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Nagasaki,                K,              Nakamura, A,                Yamauchi,            T, Kamasaki,                H, Hara,                Y, Kanno,                J, et al.            Investigation of TSH receptor blocking antibodies in childhood-onset            atrophic autoimmune thyroiditis. Clin Pediatr            Endocrinol          2021;30: 79\u201384.","DOI":"10.1297\/cpe.30.79"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Wakatsuki,                R, Shimizu,                M, Shimbo,                A, Adachi,                E,              Kanamori, T,                Yamazaki,            S, et al.            Atrophic autoimmune thyroiditis complicated with systemic lupus            erythematosus. Mod Rheumatol Case Rep          2023;7: 65\u20137.","DOI":"10.1093\/mrcr\/rxac057"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Kadowaki,                S, Hori,                T,                Matsumoto,              H, Kanda,                K, Ozeki,                M,                Shirakami,              Y, et al.            Prepubertal onset of slipped capital femoral epiphysis associated with            hypothyroidism: a case report and literature review. BMC Endocr            Disord          2017;17: 59.","DOI":"10.1186\/s12902-017-0210-6"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Inamo,              Y. A 5-year-old            boy with atrophic autoimmune thyroiditis caused by thyroid-stimulation blocking            antibodies. J Pediatr Endocrinol Metab          2011;24: 591\u20134.","DOI":"10.1515\/jpem.2011.193"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Makita,              N, Isojima,                T,              Hiwatari, M,                Kitanaka,            S, Ida,                K, Iiri,                T. Painful            thyroiditis and subsequent atrophic hypothyroidism after cord blood            transfusion. Thyroid          2011;21: 1157\u20138.","DOI":"10.1089\/thy.2010.0352"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Mizota,              M, Tamada,                I,              Hizukuri, K,                Otsubo, K,                Arima, S,                Ono,            S. Two cases of            atrophic thyroiditis with unilateral low radioiodine uptake on the right lobe in thyroid            scintigram. Pediatr Int          2005;47: 456\u20138.","DOI":"10.1111\/j.1442-200x.2005.02090.x"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Kagawa,              J, Asakura,                I, Shimizu,                N, Hibino,                K, Ito,                M, Ikegaya,                T. The            long-term effect of replacement therapy in a short girl with autoimmune atrophic            thyroiditis of prepubertal onset. Clin Pediatr            Endocrinol          2004;13: 33\u20136.","DOI":"10.1297\/cpe.13.33"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Kawahara,                K,                Tsukimoto,              I, Yokoya,                S. Atrophic            autoimmune thyroiditis with positive thyroid stimulation blocking antibody in a            prepubertal boy. Clin Pediatr Endocrinol          2000;9: 105\u201311.","DOI":"10.1297\/cpe.9.105"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Nakagawa,                Y, Toya,                K, Nasuda,                K, Iijima,                S, Kubota,                A, Natsume,                H, et al.            A boy with atrophic thyroiditis of prepubertal onset, who was positive            for TSH-binding inhibitor immunoglobulins. Acta Paediatr            Jpn          1995;37: 405\u20138.","DOI":"10.1111\/j.1442-200X.1995.tb03343.x"},{"key":"17","unstructured":"17. Otabe,              O, Nakano,                Y, Kizaki,                Z,              Kinugasa, A,                Sawada,            T. A case of            atrophic thyroiditis associated with growth failure. Clin            Pediatr Endocrinol          1999;8(Supple 12):            93\u20135."},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Isojima,              T, Shimatsu,                A, Yokoya,                S, Chihara,                K, Tanaka,                T, Hizuka,                N, et al.            Standardized centile curves and reference intervals of serum insulin-like            growth factor-I (IGF-I) levels in a normal Japanese population using the LMS            method. Endocr J          2012;59: 771\u201380.","DOI":"10.1507\/endocrj.EJ12-0110"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Suzuki,              S,              Midorikawa,            S, Fukushima,                T, Shimura,                H, Ohira,                T, Ohtsuru,                A, et al.            Thyroid Examination Unit of the Radiation Medical Science Center for the            Fukushima Health Management Survey. Systematic            determination of thyroid volume by ultrasound examination from infancy to adolescence in            Japan: the Fukushima Health Management Survey. Endocr J          2015;62: 261\u20138.","DOI":"10.1507\/endocrj.EJ14-0478"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Badrinath                Murthy, D,                Gutierrez Alvarez,              A, Vargas,                W, Litao,                MKS, Shah,                B.            Auto-destruction of the thyroid gland and coexisting glutamic acid            decarboxylase mediated neurological disease in an adolescent: an unusual presentation of            autoimmunity. J Pediatr Endocrinol Metab          2021;34: 1329\u201333.","DOI":"10.1515\/jpem-2020-0697"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Bronsky,              D, Meltzer,                JL,                Waldstein,              SS. Idiopathic            juvenile myxedema and myasthenia gravis. A case with circulating thyroid and skeletal            muscle antibodies. Am J Med          1967;43: 956\u201362.","DOI":"10.1016\/0002-9343(67)90255-0"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Wasniewska,                M, Corrias,                A, Salerno,                M, Mussa,                A, Capalbo,                D, Messina,                MF, et al.            Thyroid function patterns at Hashimoto\u2019s thyroiditis presentation in            childhood and adolescence are mainly conditioned by patients\u2019 age.            Horm Res Paediatr          2012;78: 232\u20136.","DOI":"10.1159\/000343815"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Erba\u015f,              \u0130C, Erba\u015f,                \u0130M,                Evliyao\u011flu,              O. Clinical,            biochemical, and radiological follow-up results of children and adolescents with            Hashimoto\u2019s thyroiditis: a single-center experience. J Pediatr            Endocrinol Metab          2021;34: 987\u201394.","DOI":"10.1515\/jpem-2021-0035"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. G\u00f3mez                L\u00f3pez, E,                Nso-Roca,              AP, Juste                Ruiz, M,                Cort\u00e9s Castell,              E. Hashimoto\u2019s            disease in a cohort of 29 children and adolescents. Epidemiology, clinical course, and            comorbidities in the short and long term. Arch Argent            Pediatr          2018;116: 56\u20138 (in Spanish).","DOI":"10.5546\/aap.2018.eng.56"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Jeong,              SH, Hong,                HS, Lee,                JY. The            association between thyroid echogenicity and thyroid function in pediatric and            adolescent Hashimoto\u2019s thyroiditis. Medicine            (Baltimore)          2019;98: e15055.","DOI":"10.1097\/MD.0000000000015055"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Vitti,              P, Lampis,                M, Piga,                M,                Loviselli,              A, Brogioni,                S, Rago,                T, et al.            Diagnostic usefulness of thyroid ultrasonography in atrophic            thyroiditis. J Clin Ultrasound          1994;22: 375\u20139.","DOI":"10.1002\/jcu.1870220604"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Cohen,              RJ,              Stansifer,            PD, Barrett,                O.            Radioactive iodine uptake in Hashimoto\u2019s thyroiditis.            Arch Intern Med          1965;116: 111\u20132.","DOI":"10.1001\/archinte.1965.03870010113013"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. B\u00fclow                Pedersen, I,                Laurberg,            P, Knudsen,                N,                J\u00f8rgensen,              T, Perrild,                H, Ovesen,                L, et al.            A population study of the association between thyroid autoantibodies in            serum and abnormalities in thyroid function and structure. Clin            Endocrinol (Oxf)          2005;62: 713\u201320.","DOI":"10.1111\/j.1365-2265.2005.02284.x"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Hu,                X, Chen,                Y, Shen,                Y, Tian,                R, Sheng,                Y, Que,                H. Global            prevalence and epidemiological trends of Hashimoto\u2019s thyroiditis in adults: A systematic            review and meta-analysis. Front Public Health          2022;10: 1020709.","DOI":"10.3389\/fpubh.2022.1020709"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Rivkees,                SA, Bode,                HH,                Crawford,              JD. Long-term            growth in juvenile acquired hypothyroidism: the failure to achieve normal adult            stature. N Engl J Med          1988;318: 599\u2013602.","DOI":"10.1056\/NEJM198803103181003"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Fernandez-Gonzalez,                SM, Perez                Vila, MM,                Prado-Carro,              AM. Precocious            puberty in hypothyroidism: Mini-review of Van Wyk-Grumbach syndrome.            J Endocr Soc          2023;7: bvad135.","DOI":"10.1210\/jendso\/bvad135"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. Bogner,              U, Heged\u00fcs,                L, Hansen,                JM, Finke,                R,                Schleusener,              H. Thyroid            cytotoxic antibodies in atrophic and goitrous autoimmune thyroiditis.            Eur J Endocrinol          1995;132: 69\u201374.","DOI":"10.1530\/eje.0.1320069"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. Chiovato,                L, Bassi,                P, Santini,                F, Mammoli,                C, Lapi,                P, Carayon,                P, et al.            Antibodies producing complement-mediated thyroid cytotoxicity in patients            with atrophic or goitrous autoimmune thyroiditis. J Clin            Endocrinol Metab          1993;77: 1700\u20135.","DOI":"10.1210\/jcem.77.6.7903315"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34. Zantut-Wittmann,                DE,              Persoli, L,                Tambascia,              MA, Fischer,                E, Franco                Maldonado, D,                Costa, AM,              et al. HLA-DRB1*04 and HLA-DQB1*03            association with the atrophic but not with the goitrous form of chronic autoimmune            thyroiditis in a Brazilian population. Horm Metab Res          2004;36: 492\u2013500.","DOI":"10.1055\/s-2004-825732"},{"key":"35","doi-asserted-by":"publisher","unstructured":"35. Carl\u00e9,              A, Laurberg,                P, Knudsen,                N, Perrild,                H, Ovesen,                L,                Rasmussen,              LB, et al.            Thyroid peroxidase and thyroglobulin auto-antibodies in patients with            newly diagnosed overt hypothyroidism. Autoimmunity          2006;39: 497\u2013503.","DOI":"10.1080\/08916930600907913"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36. Fountoulakis,                S,                Tsatsoulis,              A. On the            pathogenesis of autoimmune thyroid disease: a unifying hypothesis.            Clin Endocrinol (Oxf)          2004;60: 397\u2013409.","DOI":"10.1046\/j.1365-2265.2004.01978.x"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37. Sugenoya,                A, Itoh,                N, Kasuga,                Y,                Kobayashi,              S, Ohhashi,                T, Nagai,                N, et al.            Histopathological features of atrophic thyroiditis with blocking type-TSH            binding inhibitor immunoglobulins. Endocr J          1995;42: 277\u201381.","DOI":"10.1507\/endocrj.42.277"},{"key":"38","doi-asserted-by":"crossref","unstructured":"38. Adachi,              M, Takamasu,                T, Inuo,                C.            Hyponatremia secondary to severe atopic dermatitis in early            infancy. Pediatr Int          2019;61: 544\u201350.","DOI":"10.1111\/ped.13865"}],"container-title":["Clinical Pediatric Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/cpe\/34\/1\/34_2024-0040\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T23:26:40Z","timestamp":1736551600000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/cpe\/34\/1\/34_2024-0040\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.1297\/cpe.2024-0040","relation":{},"ISSN":["0918-5739","1347-7358"],"issn-type":[{"value":"0918-5739","type":"print"},{"value":"1347-7358","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"2024-0040"}}