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Coley,              BD. Caffey\u2019s pediatric          diagnostic imaging. 13th ed ed: Elsevier; 2019. 2 v. p."},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Chang,              YW, Hong,                HS, Choi,                DL.            Sonography of the pediatric thyroid: a pictorial essay.            J Clin Ultrasound          2009;37: 149\u201357.","DOI":"10.1002\/jcu.20555"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Li,                L, Zhang,                A, Chen,                D, Taragin,                BH, Luo,                X.            Preliminary study of sound touch elastography in diffuse thyroid disease            in children. Front Pediatr          2022;10: 964413.","DOI":"10.3389\/fped.2022.964413"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Bak\u0131rta\u015f                Palab\u0131y\u0131k, F,                \u0130nci, E,                Papatya \u00c7ak\u0131r,              ED, Hocao\u011flu,                E. Evaluation            of normal thyroid tissue and autoimmune thyroiditis in children using shear wave            elastography. J Clin Res Pediatr Endocrinol          2019;11: 132\u20139.","DOI":"10.4274\/jcrpe.galenos.2018.2018.0137"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Uysal,              E, \u00d6zt\u00fcrk,                M.            Quantitative assessment of thyroid glands in healthy children with shear            wave elastography. Ultrasound Q          2019;35: 297\u2013300.","DOI":"10.1097\/RUQ.0000000000000426"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Hazem,              M, Zakaria,                OM, Daoud,                MYI, Al                Jabr, IK,                AlYahya,            AA, Hassanein,                AG, et al.            Accuracy of shear wave elastography in characterization of thyroid            nodules in children and adolescents. Insights Imaging          2021;12: 128.","DOI":"10.1186\/s13244-021-01074-7"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Tritou,              I, Vakaki,                M,                Sfakiotaki,              R,              Kalaitzaki,            K, Raissaki,                M. Pediatric            thyroid ultrasound: a radiologist\u2019s checklist. Pediatr            Radiol          2020;50: 563\u201374.","DOI":"10.1007\/s00247-019-04602-2"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Suzuki,              S,              Midorikawa,            S, Fukushima,                T, Shimura,                H, Ohira,                T, Ohtsuru,                A, et al.            Thyroid Examination Unit of the Radiation Medical Science Center for the            Fukushima Health Management Survey. 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Sao Paulo Med J          2002;120: 45\u20138.","DOI":"10.1590\/S1516-31802002000200004"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Schoen,              EJ, Clapp,                W, To,                TT,              Fireman,            BH. The key role            of newborn thyroid scintigraphy with isotopic iodide (123I) in defining and managing            congenital hypothyroidism. Pediatrics          2004;114: e683\u20138.","DOI":"10.1542\/peds.2004-0803"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. LaFranchi,                SH. Approach            to the diagnosis and treatment of neonatal hypothyroidism. J            Clin Endocrinol Metab          2011;96: 2959\u201367.","DOI":"10.1210\/jc.2011-1175"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Toublanc,                JE.            Comparison of epidemiological data on congenital hypothyroidism in Europe            with those of other parts in the world. Horm Res          1992;38: 230\u20135.","DOI":"10.1159\/000182549"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Minamitani,                K. Newborn            Screening for Congenital Hypothyroidism in Japan. Int J Neonatal            Screen          2021;7: 34.","DOI":"10.3390\/ijns7030034"},{"key":"15","doi-asserted-by":"publisher","unstructured":"15. Chang,              YW, Lee,                DH, Hong,                YH, Hong,                HS, Choi,                DL, Seo,                DY.            Congenital hypothyroidism: analysis of discordant US and scintigraphic            findings. Radiology          2011;258: 872\u20139.","DOI":"10.1148\/radiol.10100290"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Van                Vliet, G,                Diaz Escagedo,              P. Redefining            congenital hypothyroidism?J Clin Endocrinol Metab          2021;106: e1463\u20135.","DOI":"10.1210\/clinem\/dgaa905"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Uehara,              E, Abe,                K,                Tanase-Nakao,              K, Muroya,                K, Hattori,                A,                Matsubara,              K, et al.            Molecular and clinical features of congenital hypothyroidism due to            multiple <i>DUOX2<\/i> variants. Thyroid          2024;34: 827\u201336.","DOI":"10.1089\/thy.2024.0046"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Mio,              C, Grani,                G, Durante,                C, Damante,                G. Molecular            defects in thyroid dysgenesis. Clin Genet          2020;97: 222\u201331.","DOI":"10.1111\/cge.13627"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Narumi,              S, Opitz,                R,              Nagasaki, K,                Muroya, K,                Asakura, Y,                Adachi, M,              et al. GWAS of thyroid dysgenesis            identifies a risk locus at 2q33.3 linked to regulation of Wnt signaling.            Hum Mol Genet          2022;31: 3967\u201374.","DOI":"10.1093\/hmg\/ddac093"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Narumi,              S, Nagasaki,                K, Kiriya,                M, Uehara,                E, Akiba,                K,                Tanase-Nakao,              K, et al.            Functional variants in a TTTG microsatellite on 15q26.1 cause familial            nonautoimmune thyroid abnormalities. Nat Genet          2024;56: 869\u201376.","DOI":"10.1038\/s41588-024-01735-5"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Karakoc-Aydiner,                E, Turan,                S, Akpinar,                I, Dede,                F, Isguven,                P, Adal,                E, et al.            Pitfalls in the diagnosis of thyroid dysgenesis by thyroid            ultrasonography and scintigraphy. Eur J Endocrinol          2012;166: 43\u20138.","DOI":"10.1530\/EJE-11-0140"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Noussios,                G,                Anagnostis,              P, Goulis,                DG, Lappas,                D, Natsis,                K. Ectopic            thyroid tissue: anatomical, clinical, and surgical implications of a rare            entity. Eur J Endocrinol          2011;165: 375\u201382.","DOI":"10.1530\/EJE-11-0461"},{"key":"23","doi-asserted-by":"publisher","unstructured":"23. 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Association between monoallelic <i>TSHR<\/i> mutations and            congenital hypothyroidism: a statistical approach. Eur J            Endocrinol          2018;178: 137\u201344.","DOI":"10.1530\/EJE-16-1049"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Adaletli,                I,                Bayramoglu,              Z, Caliskan,                E, Yilmaz,                R, Akyol                Sari, ZN,                Bas, F,              et al. Multi-parametric ultrasound            evaluation of pediatric thyroid dyshormonogenesis. Ultrasound            Med Biol          2019;45: 1644\u201353.","DOI":"10.1016\/j.ultrasmedbio.2019.03.004"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Thieme,              ET. Goiter and            deaf mutism. Ann Surg          1975;182: 173\u20136.","DOI":"10.1097\/00000658-197508000-00017"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Sugisawa,                C, Higuchi,                S, Takagi,                M,              Hasegawa, Y,                Taniyama,            M, Abe,                K, et al.            Homozygous DUOXA2 mutation (p.Tyr138<sup>*<\/sup>) in a girl with            congenital hypothyroidism and her apparently unaffected brother: Case report and review            of the literature. Endocr J          2017;64: 807\u201312.","DOI":"10.1507\/endocrj.EJ16-0564"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Tanase-Nakao,                K,                Iwahashi-Odano,              M, Sugisawa,                C, Abe,                K, Muroya,                K,              Yamamoto, Y,              et al. Genotype-phenotype correlations in            30 japanese patients with congenital hypothyroidism attributable to TG            defects. J Clin Endocrinol Metab          2024;109: 2358\u201365.","DOI":"10.1210\/clinem\/dgae098"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Tajima,              T, Nakamura,                A, Oguma,                M,              Yamazaki,            M. Recent            advances in research on isolated congenital central hypothyroidism.            Clin Pediatr Endocrinol          2019;28: 69\u201379.","DOI":"10.1297\/cpe.28.69"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Williams,                JL, Paul,                D, Bisset,              3rd,            G. Pediatr            Radiol          2013;43: 1254\u201364.","DOI":"10.1007\/s00247-013-2707-0"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. van der                Kaay, DC,                Wasserman,              JD, Palmert,                MR.            Management of neonates born to mothers with Graves\u2019            disease. Pediatrics          2016;137: e20151878.","DOI":"10.1542\/peds.2015-1878"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. H\u00e9brant,              A, van                Staveren, WC,                Maenhaut,            C, Dumont,                JE,              Lecl\u00e8re,            J. Genetic            hyperthyroidism: hyperthyroidism due to activating TSHR mutations.            Eur J Endocrinol          2011;164: 1\u20139.","DOI":"10.1530\/EJE-10-0775"},{"key":"34","doi-asserted-by":"publisher","unstructured":"34. Zimmerman,                D. Fetal and            neonatal hyperthyroidism. Thyroid          1999;9: 727\u201333.","DOI":"10.1089\/thy.1999.9.727"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35. Tessaris,                D, Corrias,                A,                Matarazzo,              P, De              Sanctis, L,                Wasniewska,              M, Messina,                MF, et al.            Thyroid abnormalities in children and adolescents with McCune-Albright            syndrome. Horm Res Paediatr          2012;78: 151\u20137.","DOI":"10.1159\/000342641"},{"key":"36","unstructured":"36. Nelson,              WE, Kliegman,                R, St.              Geme, III,              JW."},{"key":"37","doi-asserted-by":"publisher","unstructured":"37. Intenzo,                CM,              Capuzzi, DM,                Jabbour, S,                Kim, SM,                dePapp,            AE. Scintigraphic            features of autoimmune thyroiditis. Radiographics          2001;21: 957\u201364.","DOI":"10.1148\/radiographics.21.4.g01jl17957"},{"key":"38","doi-asserted-by":"crossref","unstructured":"38. Yolmo,              D, Madana,                J,                Kalaiarasi,              R,                Gopalakrishnan,              S, Kiruba                Shankar, M,                Krishnapriya,              S.            Retrospective case review of pyriform sinus fistulae of third branchial            arch origin commonly presenting as acute suppurative thyroiditis in            children. J Laryngol Otol          2012;126: 737\u201342.","DOI":"10.1017\/S0022215112000898"},{"key":"39","doi-asserted-by":"crossref","unstructured":"39. Essenmacher,                AC, Joyce,                PH, Kao,                SC,              Epelman, M,                Pesce, LM,                D\u2019Alessandro,              MP, et al.            Sonographic Evaluation of Pediatric Thyroid Nodules.            Radiographics          2017;37: 1731\u201352.","DOI":"10.1148\/rg.2017170059"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40. Squires,                JH,                Martinez-Rios,              C, Davis,                JC, Dietz,                KR,              Epelman, MS,                Lai, HA,              et al. Imaging of pediatric thyroid tumors: A COG          Diagnostic Imaging Committee\/SPR Oncology Committee White Paper. Pediatr Blood Cancer.            2023;70 Suppl 4(Suppl 4):e29957.","DOI":"10.1002\/pbc.29957"},{"key":"41","doi-asserted-by":"crossref","unstructured":"41. Dermody,              S, Walls,                A, Harley,              Jr,            EH. Int J Pediatr            Otorhinolaryngol          2016;89: 121\u20136.","DOI":"10.1016\/j.ijporl.2016.08.005"},{"key":"42","unstructured":"42. Sperling,                M. Pediatric endocrinology.          4th ed ed: Saunders\/Elsevier; 2014."},{"key":"43","doi-asserted-by":"crossref","unstructured":"43. LaFranchi,                SH. Inaugural            management guidelines for children with thyroid nodules and differentiated thyroid            cancer: children are not small adults. Thyroid          2015;25: 713\u20135.","DOI":"10.1089\/thy.2015.0275"},{"key":"44","doi-asserted-by":"publisher","unstructured":"44. Moon,              WJ, Jung,                SL, Lee,                JH, Na,                DG, Baek,                JH, Lee,                YH, et al.            Thyroid Study Group, Korean Society of Neuro- and Head and Neck            Radiology. Benign and malignant thyroid nodules: US            differentiation--multicenter retrospective study.            Radiology          2008;247: 762\u201370.","DOI":"10.1148\/radiol.2473070944"},{"key":"45","doi-asserted-by":"publisher","unstructured":"45. Francis,                GL,                Waguespack,              SG, Bauer,                AJ,              Angelos, P,                Benvenga,            S, Cerutti,                JM, et al.            American Thyroid Association Guidelines Task Force.            Management guidelines for children with thyroid nodules and            differentiated thyroid cancer. Thyroid          2015;25: 716\u201359.","DOI":"10.1089\/thy.2014.0460"},{"key":"46","doi-asserted-by":"crossref","unstructured":"46. Chng,              CL, Kocjan,                G,                Kurzawinski,              TR, Beale,                T.            Intrathyroidal ectopic thymic tissue mimicking thyroid cancer in            children. 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