{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T05:12:24Z","timestamp":1783746744246,"version":"3.55.0"},"reference-count":44,"publisher":"Japanese Society for Pediatric Endocrinology","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pediatr Endocrinol"],"published-print":{"date-parts":[[2026]]},"DOI":"10.1297\/cpe.2026-0021","type":"journal-article","created":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T22:11:41Z","timestamp":1783375901000},"page":"215-223","source":"Crossref","is-referenced-by-count":0,"title":["Uterine artery pulsatility index as a functional biomarker of central precocious puberty: a scoping review"],"prefix":"10.1297","volume":"35","author":[{"given":"Ignazio","family":"Cammisa","sequence":"first","affiliation":[{"name":"Department of Pediatrics, San Giovanni Evangelista Hospital, Tivoli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donato","family":"Rigante","sequence":"additional","affiliation":[{"name":"Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"},{"name":"Universit\u00e0 Cattolica Sacro Cuore, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clelia","family":"Cipolla","sequence":"additional","affiliation":[{"name":"Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"125","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Latronico, AC, Brito, VN, Carel, JC. Causes, diagnosis, and treatment of central precocious puberty. Lancet Diabetes Endocrinol 2016;4: 265\u201374.","DOI":"10.1016\/S2213-8587(15)00380-0"},{"key":"2","unstructured":"2. Turriziani Colonna, A, Curatola, A, Sodero, G, Lazzareschi, I, Cammisa, I, Cipolla, C. Central precocious puberty in children after COVID-19 outbreak: a single-center retrospective study. Minerva Pediatr (Torino) 2025;77: 306\u201313."},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Cammisa, I, Malavolta, E, Arzilli, F, Rotunno, G, Rigante, D, Cipolla, C. The effect of GnRH analogs on body mass index in girls with central precocious puberty: a single-center retrospective study with a literature review. Children (Basel) 2025;12: 336.","DOI":"10.3390\/children12030336"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Aguirre, RS, Eugster, EA. Central precocious puberty: From genetics to treatment. Best Pract Res Clin Endocrinol Metab 2018;32: 343\u201354.","DOI":"10.1016\/j.beem.2018.05.008"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Zevin, EL, Eugster, EA. Central precocious puberty: a review of diagnosis, treatment, and outcomes. Lancet Child Adolesc Health 2023;7: 886\u201396.","DOI":"10.1016\/S2352-4642(23)00237-7"},{"key":"6","unstructured":"6. Miranda-Lora, AL, Torres-Tamayo, M, Zurita-Cruz, JN, Aguilar-Herrera, BE, Calzada-Le\u00f3n, R, Rivera-Hern\u00e1ndez, AJ, et al. Diagnosis of precocious puberty: clinical guideline for the diagnosis and treatment of precocious puberty. Bol Med Hosp Infant Mex 2020;77(Supl 1): 7\u201314."},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Brito, VN, Latronico, AC, Arnhold, IJ, Mendon\u00e7a, BB. Update on the etiology, diagnosis and therapeutic management of sexual precocity. Arq Bras Endocrinol Metabol 2008;52: 18\u201331.","DOI":"10.1590\/S0004-27302008000100005"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Kan, L, He, D, Yue, W. The combined diagnostic and therapeutic value of ultrasound and X-ray bone age index in girls with idiopathic central precocious puberty. Endocr Connect 2025;14: e250354.","DOI":"10.1530\/EC-25-0354"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Iughetti, L, Predieri, B, Ferrari, M, Gallo, C, Livio, L, Milioli, S, et al. Diagnosis of central precocious puberty: endocrine assessment. J Pediatr Endocrinol Metab 2000;13(Suppl 1): 709\u201315.","DOI":"10.1515\/JPEM.2000.13.S1.709"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Cheuiche, AV, da Silveira, LG, de Paula, LCP, Lucena, IRS, Silveiro, SP. Diagnosis and management of precocious sexual maturation: an updated review. Eur J Pediatr 2021;180: 3073\u201387.","DOI":"10.1007\/s00431-021-04022-1"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Cheuiche, AV, Moro, C, Lucena, IRS, de Paula, LCP, Silveiro, SP. Accuracy of doppler assessment of the uterine arteries for the diagnosis of pubertal onset in girls: a scoping review. Sci Rep 2023;13: 5791.","DOI":"10.1038\/s41598-023-32880-2"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Sessa, L, Rotunno, G, Sodero, G, Pane, LC, Rendeli, C, Maresca, G, et al. Predictive value of transabdominal pelvic ultrasonography for the diagnosis of central precocious puberty: A single-center observational retrospective study. Clin Pediatr Endocrinol 2024;33: 199\u2013206.","DOI":"10.1297\/cpe.2024-0025"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Kongmanas, HB, Trinavarat, P, Wacharasindhu, S. Sensitivity and specificity of using pelvic ultrasonographic parameters combined with basal gonadotropin levels to diagnose central precocious puberty in Thai girls. Asian Biomed Res Rev News 2021;15: 27\u201334.","DOI":"10.2478\/abm-2021-0004"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Nguyen, NN, Huynh, LBP, Do, MD, Yang, TY, Tsai, MC, Chen, YC. Diagnostic accuracy of female pelvic ultrasonography in differentiating precocious puberty from premature thelarche: a systematic review and meta-analysis. Front Endocrinol (Lausanne) 2021;12: 735875.","DOI":"10.3389\/fendo.2021.735875"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Battaglia, C, Regnani, G, Mancini, F, Iughetti, L, Venturoli, S, Flamigni, C. Pelvic sonography and uterine artery color Doppler analysis in the diagnosis of female precocious puberty. Ultrasound Obstet Gynecol 2002;19: 386\u201391.","DOI":"10.1046\/j.1469-0705.2002.00669.x"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Br\u00e4nnstr\u00f6m, M, Norman, RJ. Involvement of leukocytes and cytokines in the ovulatory process and corpus luteum function. Hum Reprod 1993;8: 1762\u201375.","DOI":"10.1093\/oxfordjournals.humrep.a137929"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Findlay, JK. Angiogenesis in reproductive tissues. J Endocrinol 1986;111: 357\u201366.","DOI":"10.1677\/joe.0.1110357"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Laursen, EM, Holm, K, Brocks, V, Jarden, M, M\u00fcller, J. Doppler assessment of flow velocity in the uterine artery during pubertal maturation. Ultrasound Obstet Gynecol 1996;8: 341\u20135.","DOI":"10.1046\/j.1469-0705.1996.08050341.x"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Ziereisen, F, Heinrichs, C, Dufour, D, Saerens, M, Avni, EF. The role of Doppler evaluation of the uterine artery in girls around puberty. Pediatr Radiol 2001;31: 712\u20139.","DOI":"10.1007\/s002470100463"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Battaglia, C, Salvatori, M, Gallinelli, A, Artini, PG, Genazzani, AR, Volpe, A. Color Doppler and hormone replacement therapy: the role of thromboxane and plasma viscosity. Gynecol Endocrinol 1999;13: 183\u20138.","DOI":"10.3109\/09513599909167553"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Battaglia, C, Mancini, F, Regnani, G, Persico, N, Iughetti, L, De Aloysio, D. Pelvic ultrasound and color Doppler findings in different isosexual precocities. Ultrasound Obstet Gynecol 2003;22: 277\u201383.","DOI":"10.1002\/uog.154"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Golestani, R, Sheikhvatan, M, Behpour, AM, Mehdizadeh, M, Hajiashrafi, AA. Relationship between uterine and ovarian arterial blood flow measured by Doppler sonography at different stages of puberty. Taiwan J Obstet Gynecol 2008;47: 62\u20135.","DOI":"10.1016\/S1028-4559(08)60056-X"},{"key":"23","unstructured":"23. Linares, J, Espinoza, A, Riquelme, J, Avila, A, Cassorla, F. Doppler evaluation of the uterine artery for the diagnosis and follow-up of patients with precocious puberty. ESPE Abstract  2015."},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Paesano, PL, Colantoni, C, Mora, S, di Lascio, A, Ferrario, M, Esposito, A, et al. Validation of an accurate and noninvasive tool to exclude female precocious puberty: pelvic ultrasound with uterine artery pulsatility index. AJR Am J Roentgenol 2019;213: 451\u20137.","DOI":"10.2214\/AJR.18.19875"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Cheuiche, AV, da Silveira, LG, Escott, GM, Lucena, IRS, Pu\u00f1ales, M, Costenaro, F, et al. Accuracy of Doppler assessment of the uterine arteries in healthy girls for the diagnosis of pubertal onset. Endocrine 2022;76: 172\u20138.","DOI":"10.1007\/s12020-021-02948-y"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Bertoncello, FZ, Beust, MF, Tagliari, CM, Herter, LD, Kopacek, C. Correlation of pelvic ultrasonography with pubertal development in girls. Rev Bras Ginecol Obstet 2024;46: e-rbgo5.","DOI":"10.61622\/rbgo\/2024AO05"},{"key":"27","unstructured":"27. Gonz\u00e1lez N\u00fa\u00f1ez, A, P\u00e9rez Rivera, DK, Herrera Flores, I. Effectiveness of the uterine artery pulsatility index as a non-invasive diagnostic method for precocious puberty and its correlation with pelvic and breast ultrasound findings, bone age, and hormonal profile. ESPE Abstract 2024."},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Cheuiche, AV, da Silveira, LG, Lucena, IRS, Pu\u00f1ales, M, Costenaro, F, Kopacek, C, et al. Doppler assessment of the uterine arteries is a valuable adjunct tool for the evaluation of efficacy of gonadotropin-releasing hormone agonist therapy in girls with central precocious puberty. Neuroendocrinology 2025;115: 520\u20139.","DOI":"10.1159\/000544985"},{"key":"29","unstructured":"29. De Rosa, G, Pardeo, M, Rigante, D. Current recommendations for the pharmacologic therapy in Kawasaki syndrome and management of its cardiovascular complications. Eur Rev Med Pharmacol Sci 2007;11: 301\u20138."},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Rigante, D, Valentini, P, Rizzo, D, Leo, A, De Rosa, G, Onesimo, R, et al. Responsiveness to intravenous immunoglobulins and occurrence of coronary artery abnormalities in a single-center cohort of Italian patients with Kawasaki syndrome. Rheumatol Int 2010;30: 841\u20136.","DOI":"10.1007\/s00296-009-1337-1"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Grande Gutierrez, N, Mathew, M, McCrindle, BW, Tran, JS, Kahn, AM, Burns, JC, et al. Hemodynamic variables in aneurysms are associated with thrombotic risk in children with Kawasaki disease. Int J Cardiol 2019;281: 15\u201321.","DOI":"10.1016\/j.ijcard.2019.01.092"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. Chu, C, He, L, Lin, YX, Xie, LP, Liu, F. Giant bilateral axillary artery aneurysms with left complete obstructive thrombus in intravenous immunoglobulin-sensitive Kawasaki disease: a case report. Pediatr Rheumatol Online J 2021;19: 157.","DOI":"10.1186\/s12969-021-00643-w"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. Ziereisen, F, Guissard, G, Damry, N, Avni, EF. Sonographic imaging of the paediatric female pelvis. Eur Radiol 2005;15: 1296\u2013309.","DOI":"10.1007\/s00330-005-2648-6"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34. de Vries, L, Phillip, M. Role of pelvic ultrasound in girls with precocious puberty. Horm Res Paediatr 2011;75: 148\u201352.","DOI":"10.1159\/000323361"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35. Orsini, LF, Salardi, S, Pilu, G, Bovicelli, L, Cacciari, E. Pelvic organs in premenarcheal girls: real-time ultrasonography. Radiology 1984;153: 113\u20136.","DOI":"10.1148\/radiology.153.1.6473771"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36. Sample, WF, Lippe, BM, Gyepes, MT. Gray-scale ultrasonography of the normal female pelvis. Radiology 1977;125: 477\u201383.","DOI":"10.1148\/125.2.477"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37. Siegel, MJ. Pediatric gynecologic sonography. Radiology 1991;179: 593\u2013600.","DOI":"10.1148\/radiology.179.3.2027956"},{"key":"38","doi-asserted-by":"crossref","unstructured":"38. Salardi, S, Orsini, LF, Cacciari, E, Bovicelli, L, Tassoni, P, Reggiani, A. Pelvic ultrasonography in premenarcheal girls: relation to puberty and sex hormone concentrations. Arch Dis Child 1985;60: 120\u20135.","DOI":"10.1136\/adc.60.2.120"},{"key":"39","doi-asserted-by":"crossref","unstructured":"39. Kim, YH, Lee, HJ, Shin, JE, Lee, Y, Shin, JC, Park, TC, et al. The predictive value of the uterine artery pulsatility index during the early third trimester for the occurrence of adverse pregnancy outcomes depending on the maternal obesity. Obes Res Clin Pract 2015;9: 374\u201381.","DOI":"10.1016\/j.orcp.2014.12.001"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40. Cavoretto, PI, Salmeri, N, Candiani, M, Farina, A. Reference ranges of uterine artery pulsatility index from first to third trimester based on serial Doppler measurements: longitudinal cohort study. Ultrasound Obstet Gynecol 2023;61: 474\u201380.","DOI":"10.1002\/uog.26092"},{"key":"41","doi-asserted-by":"crossref","unstructured":"41. Horgan, R, Sinkovskaya, E, Saade, G, Kalafat, E, Rice, MM, Heeze, A, et al. Longitudinal assessment of spiral and uterine arteries in normal pregnancy using novel ultrasound tool. Ultrasound Obstet Gynecol 2023;62: 860\u20136.","DOI":"10.1002\/uog.26312"},{"key":"42","unstructured":"42. Medina Castro, N, Figueroa Diesel, H, Guzm\u00e1n Huerta, M, Hern\u00e1ndez Andrade, E. Valores de referencia del \u00edndice de pulsatilidad de las arterias uterina y umbilical durante el embarazo. Ginecol Obstet Mex 2006;74: 509\u201315 (in Spanish)."},{"key":"43","doi-asserted-by":"crossref","unstructured":"43. Plasencia, W, Barber, MA, Alvarez, EE, Segura, J, Valle, L, Garcia-Hernandez, JA. Comparative study of transabdominal and transvaginal uterine artery Doppler pulsatility indices at 11-13 + 6 weeks. Hypertens Pregnancy 2011;30: 414\u201320.","DOI":"10.3109\/10641955.2010.506232"},{"key":"44","doi-asserted-by":"crossref","unstructured":"44. Lefebvre, J, Demers, S, Bujold, E, Nicolaides, KH, Girard, M, Brassard, N, et al. Comparison of two different sites of measurement for transabdominal uterine artery Doppler velocimetry at 11-13 weeks. Ultrasound Obstet Gynecol 2012;40: 288\u201392.","DOI":"10.1002\/uog.11137"}],"container-title":["Clinical Pediatric Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/cpe\/35\/3\/35_2026-0021\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T04:23:57Z","timestamp":1783743837000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/cpe\/35\/3\/35_2026-0021\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":44,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.1297\/cpe.2026-0021","relation":{},"ISSN":["0918-5739","1347-7358"],"issn-type":[{"value":"0918-5739","type":"print"},{"value":"1347-7358","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"article-number":"2026-0021"}}