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Meehan,              CA, Cochran,                E, Kassai,                A, Brown,                RJ, Gorden,                P.            Metreleptin for injection to treat the complications of leptin deficiency            in patients with congenital or acquired generalized lipodystrophy.            Expert Rev Clin Pharmacol          2016;9: 59\u201368.","DOI":"10.1586\/17512433.2016.1096772"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Brown,              RJ,                Araujo-Vilar,              D, Cheung,                PT, Dunger,                D, Garg,                A, Jack,                M, et al.            The diagnosis and management of lipodystrophy syndromes: a multi-society            practice guideline. J Clin Endocrinol Metab          2016;101: 4500\u201311.","DOI":"10.1210\/jc.2016-2466"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Ebihara,              K, Kusakabe,                T,              Masuzaki, H,                Kobayashi,              N, Tanaka,                T, Chusho,                H, et al.            Gene and phenotype analysis of congenital generalized lipodystrophy in            Japanese: a novel homozygous nonsense mutation in seipin gene. J            Clin Endocrinol Metab          2004;89: 2360\u20134.","DOI":"10.1210\/jc.2003-031211"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Haque,              WA,              Shimomura, I,                Matsuzawa,              Y, Garg,                A. Serum            adiponectin and leptin levels in patients with lipodystrophies.            J Clin Endocrinol Metab          2002;87: 2395.","DOI":"10.1210\/jcem.87.5.8624"},{"key":"5","doi-asserted-by":"publisher","unstructured":"5. Chou,              K, Perry,                CM.            Metreleptin: first global approval.            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Eur J Endocrinol          2010;162: 1083\u201391.","DOI":"10.1530\/EJE-09-1027"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Takeyari,                S,              Takakuwa, S,                Miyata, K,                Yamamoto,            K, Nakayama,                H, Ohata,                Y, et al.            Metreleptin treatment for congenital generalized lipodystrophy type 4            (CGL4): a case report. Clin Pediatr Endocrinol          2019;28: 1\u20137.","DOI":"10.1297\/cpe.28.1"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Erhardt,              E, Foraita,                R, Pigeot,                I, Barba,                G,                Veidebaum,              T,              Tornaritis,            M, et al.            IDEFICS consortium. Reference values for            leptin and adiponectin in children below the age of 10 based on the IDEFICS            cohort. 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Pharmacologic treatment strategies in children with type 2 diabetes            mellitus. Clin Pediatr Endocrinol          2013;22: 1\u20138.","DOI":"10.1297\/cpe.22.1"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Dutil,              C, Chaput,                JP.            Inadequate sleep as a contributor to type 2 diabetes in children and            adolescents. Nutr Diabetes          2017;7: e266.","DOI":"10.1038\/nutd.2017.19"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Marcovecchio,                ML,                Chiarelli,              F. The effects            of acute and chronic stress on diabetes control. Sci            Signal          2012;5: pt10.","DOI":"10.1126\/scisignal.2003508"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Rudnicka,                AR,                Nightingale,              CM, Donin,                AS, Sattar,                N, Cook,                DG,              Whincup, PH,              et al. Sleep Duration and Risk of Type 2            Diabetes. 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