{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T00:25:22Z","timestamp":1716942322265},"reference-count":29,"publisher":"Baishideng Publishing Group Inc.","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Clin Cases"],"abstract":"BACKGROUND<\/jats:p>\n For patients with acute paraplegia caused by spinal giant cell tumor (GCT) who require emergency decompressive surgery, there is still a lack of relevant reports on surgical options. This study is the first to present the case of an acute paraplegic patient with a thoracic spinal GCT who underwent an emergency total en bloc spondylectomy (TES). Despite tumor recurrence, three-level TES was repeated after denosumab therapy.<\/jats:p>\n CASE SUMMARY<\/jats:p>\n A 27-year-old female patient who underwent single-level TES in an emergency presented with sudden severe back pain and acute paraplegia due to a thoracic spinal tumor. After emergency TES, the patient's spinal cord function recovered, and permanent paralysis was avoided. The postoperative histopathological examination revealed that the excised neoplasm was a rare GCT. Unfortunately, the tumor recurred 9 months after the first surgery. After 12 months of denosumab therapy, the tumor size was reduced, and tumor calcification. To prevent recurrent tumor progression and provide a possible cure, a three-level TES was performed again. The patient returned to an active lifestyle 1 month after the second surgery, and no recurrence of GCT was found at the last follow-up.<\/jats:p>\n CONCLUSION<\/jats:p>\n This patient with acute paraplegia underwent TES twice, including once in an emergency, and achieved good therapeutic results. TES in emergency surgery is feasible and safe when conditions permit; however, it may increase the risk of tumor recurrence.<\/jats:p>","DOI":"10.12998\/wjcc.v12.i16.2894","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T06:55:01Z","timestamp":1716879301000},"page":"2894-2903","source":"Crossref","is-referenced-by-count":0,"title":["Thoracic giant cell tumor after two total en bloc<\/i> spondylectomies including one emergency surgery: A case report"],"prefix":"10.12998","volume":"12","author":[{"given":"Hai-Feng","family":"Liang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng-Na","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qin-Ming","family":"Fei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2024,6,6]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13153647"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-015-1835-9"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1111\/os.12375"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-022-07455-w"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2019.03.185"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.O.00156"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.21037\/jss-20-652"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-012-2707-6"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.4103\/0366-6999.208239"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-019-2029-4"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1579746"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-015-3777-5"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-005-0964-y"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-015-4348-5"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-018-5761-3"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1080\/00207454.2022.2079499"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1159\/000497379"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-017-5086-7"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2017.6655"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.3171\/spi.2007.6.6.15"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-014-3625-z"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3182233ccd"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyac018"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.580605"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001191"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/496351"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1111\/os.12561"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-015-4249-2"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/767198"}],"container-title":["World Journal of Clinical Cases"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/2307-8960\/full\/v12\/i16\/2894.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/2307-8960\/full\/v12\/i16\/2894.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T06:56:45Z","timestamp":1716879405000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/2307-8960\/full\/v12\/i16\/2894.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,6]]},"references-count":29,"journal-issue":{"issue":"16"},"URL":"https:\/\/doi.org\/10.12998\/wjcc.v12.i16.2894","relation":{},"ISSN":["2307-8960"],"issn-type":[{"value":"2307-8960","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6,6]]}}}