{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T15:19:07Z","timestamp":1717773547169},"reference-count":21,"publisher":"Baishideng Publishing Group Inc.","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Clin Cases"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n          <jats:p>Acute pancreatitis is a rare extrapulmonary manifestation of coronavirus disease 2019 (COVID-19) but its full correlation with COVID-19 infection remains unknown.<\/jats:p>\n          <jats:p>AIM<\/jats:p>\n          <jats:p>To identify acute pancreatitis\u2019 occurrence, clinical presentation and outcomes in a cohort of kidney transplant recipients with acute COVID-19.<\/jats:p>\n          <jats:p>METHODS<\/jats:p>\n          <jats:p>A retrospective observational single-centre cohort study from a transplant centre in Croatia for all adult renal transplant recipients with a functioning kidney allograft between March 2020 and August 2022 to record cases of acute pancreatitis during acute COVID-19. Data were obtained from hospital electronic medical records. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was proven by a positive SARS-CoV-2 real-time reverse transcriptase-polymerase chain reaction on the nasopharyngeal swab.<\/jats:p>\n          <jats:p>RESULTS<\/jats:p>\n          <jats:p>Four hundred and eight out of 1432 (28.49%) patients who received a renal allograft developed COVID-19 disease. The analyzed cohort included 321 patients (57% males). One hundred and fifty patients (46.7%) received at least one dose of the anti-SARS-CoV-2 vaccine before the infection. One hundred twenty-five (39.1%) patients required hospitalization, 141 (44.1%) developed pneumonia and four patients (1.3%) required mechanical ventilation. Treatment included immunosuppression modification in 233 patients (77.1%) and remdesivir in 53 patients (16.6%), besides the other supportive measures. In the study cohort, only one transplant recipient (0.3%) developed acute pancreatitis during acute COVID-19, presenting with abdominal pain and significantly elevated pancreatic enzymes. She survived without complications with a stable kidney allograft function.<\/jats:p>\n          <jats:p>CONCLUSION<\/jats:p>\n          <jats:p>Although rare, acute pancreatitis may complicate the course of acute COVID-19 in kidney transplant recipients. The mechanism of injury to the pancreas and its correlation with the severity of the COVID-19 infection in kidney transplant recipients warrants further research.<\/jats:p>","DOI":"10.12998\/wjcc.v12.i6.1104","type":"journal-article","created":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T05:36:57Z","timestamp":1708407417000},"page":"1104-1110","source":"Crossref","is-referenced-by-count":1,"title":["Acute pancreatitis as a complication of acute COVID-19 in kidney transplant recipients"],"prefix":"10.12998","volume":"12","author":[{"given":"Nikolina","family":"Basic-Jukic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivana","family":"Juric","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lea","family":"Katalinic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vesna","family":"Furic-Cunko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vibor","family":"Sesa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Mrzljak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2024,2,26]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pan.2013.07.063"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.405"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.23750\/abm.v91i1.9397"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(20)30126-6"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2020.03.044"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.pan.2023.10.013"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1007\/s12328-022-01633-5"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.12371"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.21926\/obm.hg.1903029"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.pan.2020.04.021"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.11657"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2020.03.055"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.663646"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1016\/j.idnow.2021.07.002"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.hbpd.2023.03.004"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30183-5"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.pan.2020.05.016"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-020-00408-4"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1097\/MPA.0000000000001770"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-09170-4"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000002160"}],"container-title":["World Journal of Clinical Cases"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/2307-8960\/full\/v12\/i6\/1104.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/2307-8960\/full\/v12\/i6\/1104.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T05:37:49Z","timestamp":1708407469000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/2307-8960\/full\/v12\/i6\/1104.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,26]]},"references-count":21,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.12998\/wjcc.v12.i6.1104","relation":{},"ISSN":["2307-8960"],"issn-type":[{"value":"2307-8960","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2,26]]}}}