{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T04:06:08Z","timestamp":1747195568443,"version":"3.40.5"},"reference-count":15,"publisher":"Baishideng Publishing Group Inc.","issue":"22","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Clin Cases"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n          <jats:p>Epstein-Barr virus (EBV)-positive T-cell\/natural killer (NK)-cell lymphoproliferative disorder is a rare but challenging condition that requires multidisciplinary teamwork, including co-management by infection medicine, radiotherapy, rehabilitation, and psychology experts, as well as wound specialist nurses.<\/jats:p>\n          <jats:p>CASE SUMMARY<\/jats:p>\n          <jats:p>The patient was a 33-year-old female who presented with an erythema-like lesion on the left upper extremity that became desquamated and then blistered and eventually became a giant ulcer with exposed nerves and muscles. The left wrist had a fixed posture, and pathology tests showed cutaneous EBV-positive NK\/T-cell proliferative disease. We employed a multidisciplinary collaborative treatment approach, and after 13 wound changes over 45 days, combined with radiation therapy, dietary supplementation, and psychosocial therapy, the left upper extremity wound healed.<\/jats:p>\n          <jats:p>CONCLUSION<\/jats:p>\n          <jats:p>Giant ulcers caused by cutaneous EBV-positive NK\/T-cell proliferative disease can be treated using a multidisciplinary collaborative approach.<\/jats:p>","DOI":"10.12998\/wjcc.v13.i22.104258","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T03:49:07Z","timestamp":1747108147000},"source":"Crossref","is-referenced-by-count":0,"title":["Giant cutaneous ulcer in Epstein-Barr virus positive T-cell\/NK-cell lymphoproliferative disorder: A case report"],"prefix":"10.12998","volume":"13","author":[{"given":"Ya-Ping","family":"Guo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi-Xin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu-Li","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2025,8,6]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2019.00071"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2018.00289"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.13315\/j.cnki.cjcep.2018.10.014"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000822624.99191.d1"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000797948.13759.ba"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtv.2017.09.002"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2014.03.003"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/S1674-8301(12)60023-2"},{"key":"B9","unstructured":"Keyal U, Bhatta AK, Wang XL. UVA1 a promising approach for scleroderma. Am J Transl Res 2017; 4280-4287"},{"key":"B10","unstructured":"Du WW. Effect of combined treatment of patients with brachial plexus nerve injury by electroacupuncture and rehabilitation training on the functional recovery of the upper limb. Shijie Zuixin Yixue Xinxi Wenzhai 2020; 52-53"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10040775"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2017.26.1.20"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.1672-5972.2025.01.013"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.issn.1674-2907.2013.14.047"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2013.08.040"}],"container-title":["World Journal of Clinical Cases"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/2307-8960\/full\/v13\/i22\/104258.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/2307-8960\/full\/v13\/i22\/104258.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T03:49:18Z","timestamp":1747108158000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/2307-8960\/full\/v13\/i22\/104258.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,6]]},"references-count":15,"journal-issue":{"issue":"22"},"alternative-id":["104258"],"URL":"https:\/\/doi.org\/10.12998\/wjcc.v13.i22.104258","relation":{},"ISSN":["2307-8960"],"issn-type":[{"value":"2307-8960","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8,6]]}}}