{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T09:18:43Z","timestamp":1792142323099,"version":"4.4.0"},"reference-count":0,"publisher":"British Editorial Society of Bone & Joint Surgery","issue":"1","license":[{"start":{"date-parts":[[1998,1,1]],"date-time":"1998-01-01T00:00:00Z","timestamp":883612800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/online.boneandjoint.org.uk\/TDM"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Bone and Joint Surgery. British volume"],"published-print":{"date-parts":[[1998,1]]},"abstract":"<jats:p>We have evaluated the use of a synthetic porous ceramic (Triosite) as a substitute for bone graft in posterior spinal fusion for idiopathic scoliosis. In a prospective, randomised study 341 patients at five hospitals in the UK and France were randomly allocated either to autograft from the iliac crest or rib segments (171) or to receive Triosite blocks (170). All patients were assessed after operation and at 3, 6, 12 and 18 months.<\/jats:p>\n                  <jats:p>The two groups were similar with regard to all demographic and baseline variables, but the 184 treated in France (54%) had Cotrel-Dubouset instrumentation and the 157 treated in the UK usually had Harrington-Luque implants. In the Triosite group the average Cobb angle of the upper curve was 56\u00b0, corrected to 24\u00b0 (57%). At 18 months, the average was 26\u00b0 (3% loss). In the autograft group the average preoperative upper curve of 53\u00b0 was corrected to 21\u00b0 (60%). At 18 months the mean curve was 25\u00b0 (8% loss). Pain levels after operation were similar in the two groups, being mild in most cases. In the Triosite group only three patients had problems of wound healing, but in the autograft group, 14 patients had delayed healing, infection or haematoma in the spinal wound. In addition, 15 autograft patients had pain at the donor site at three months. Seven had infections, two had haematoma and four had delayed healing.<\/jats:p>\n                  <jats:p>The haematological and serum biochemistry results showed no abnormal trends and no significant differences between the groups. There were no adverse events related to the graft material and no evidence of allergenicity.<\/jats:p>\n                  <jats:p>Our results suggest that Triosite synthetic porous ceramic is a safe and effective substitute for autograft in these patients. Histological findings on biopsy indicate that Triosite provides a favourable scaffolding for the formation of new bone and is gradually incorporated into the fusion mass.<\/jats:p>","DOI":"10.1302\/0301-620x.80b1.0800013","type":"journal-article","created":{"date-parts":[[2018,2,21]],"date-time":"2018-02-21T06:52:02Z","timestamp":1519195922000},"page":"13-18","source":"Crossref","is-referenced-by-count":385,"title":["Synthetic porous ceramic compared with autograft in scoliosis surgery"],"prefix":"10.1302","volume":"80-B","author":[{"given":"A. O.","family":"Ransford","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Morley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. A.","family":"Edgar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Webb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Passuti","sequence":"additional","affiliation":[{"name":"Clinique Chirurgicale Orthop\u00e9dique, Centre Hospitalier R\u00e9gional et Universitaire de Nantes, H\u00f4tel Dieu, Place Alexis Ricordeau, BP 1005, 44035 Nantes Cedex 0I, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Chopin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Morin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Michel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Garin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Pries","sequence":"additional","affiliation":[{"name":"CHRU Jean Bernard, 350 Avenue Jacquest Coeur, 86000 Poitiers, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"42","container-title":["The Journal of Bone and Joint Surgery. British volume"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/pdf\/10.1302\/0301-620X.80B1.0800013","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/pdf\/10.1302\/0301-620X.80B1.0800013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T15:26:52Z","timestamp":1629127612000},"score":1,"resource":{"primary":{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/10.1302\/0301-620X.80B1.0800013"}},"subtitle":["A PROSPECTIVE, RANDOMISED STUDY OF 341 PATIENTS"],"short-title":[],"issued":{"date-parts":[[1998,1]]},"references-count":0,"aliases":["10.1302\/0301-620x.80b1.7276","10.1302\/0301-620x.80b1.7276","10.1302\/0301-620x.80b1.7276"],"journal-issue":{"issue":"1","published-print":{"date-parts":[[1998,1]]}},"alternative-id":["10.1302\/0301-620X.80B1.0800013"],"URL":"https:\/\/doi.org\/10.1302\/0301-620x.80b1.0800013","relation":{},"ISSN":["0301-620X","2044-5377"],"issn-type":[{"value":"0301-620X","type":"print"},{"value":"2044-5377","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,1]]}}}