{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T03:32:18Z","timestamp":1793331138776,"version":"4.5.0"},"reference-count":0,"publisher":"British Editorial Society of Bone & Joint Surgery","issue":"6","license":[{"start":{"date-parts":[[1999,11,1]],"date-time":"1999-11-01T00:00:00Z","timestamp":941414400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/online.boneandjoint.org.uk\/TDM"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Bone and Joint Surgery. British volume"],"published-print":{"date-parts":[[1999,11]]},"abstract":"<jats:p> We have summarised the clinical and pathological changes in the knees of three patients in whom aqueous chlorhexidine 0.02% had been used as the irrigation solution during arthroscopically-assisted reconstruction of the anterior cruciate ligament. Even very dilute solutions of chlorhexidine can cause marked chondrolysis of articular cartilage leading to severe permanent damage to the knee. Irrigation solutions should be checked carefully to ensure that their composition is appropriate to the procedure being carried out. Exposure of articular cartilage to chlorhexidine should be avoided. <\/jats:p>","DOI":"10.1302\/0301-620x.81b6.0810995","type":"journal-article","created":{"date-parts":[[2018,2,21]],"date-time":"2018-02-21T11:50:51Z","timestamp":1519213851000},"page":"995-996","source":"Crossref","is-referenced-by-count":80,"title":["Chlorhexidine and chondrolysis in the knee"],"prefix":"10.1302","volume":"81-B","author":[{"given":"A. L.","family":"van Huyssteen","sequence":"first","affiliation":[{"name":"Department of Trauma and Orthopaedic Surgery, Royal Cornwall Hospitals Trust, Treliske Hospital, Truro, Cornwall TR1 3LJ, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. J.","family":"Bracey","sequence":"additional","affiliation":[{"name":"Department of Trauma and Orthopaedic Surgery, Royal Cornwall Hospitals Trust, Treliske Hospital, Truro, Cornwall TR1 3LJ, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"42","container-title":["The Journal of Bone and Joint Surgery. British volume"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/pdf\/10.1302\/0301-620X.81B6.0810995","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/pdf\/10.1302\/0301-620X.81B6.0810995","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T19:21:03Z","timestamp":1629141663000},"score":1,"resource":{"primary":{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/10.1302\/0301-620X.81B6.0810995"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,11]]},"references-count":0,"aliases":["10.1302\/0301-620x.81b6.9719","10.1302\/0301-620x.81b6.9719"],"journal-issue":{"issue":"6","published-print":{"date-parts":[[1999,11]]}},"alternative-id":["10.1302\/0301-620X.81B6.0810995"],"URL":"https:\/\/doi.org\/10.1302\/0301-620x.81b6.0810995","relation":{},"ISSN":["0301-620X","2044-5377"],"issn-type":[{"value":"0301-620X","type":"print"},{"value":"2044-5377","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,11]]}}}