{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T04:26:00Z","timestamp":1775535960696,"version":"3.50.1"},"reference-count":0,"publisher":"British Editorial Society of Bone & Joint Surgery","issue":"3","license":[{"start":{"date-parts":[[2000,4,1]],"date-time":"2000-04-01T00:00:00Z","timestamp":954547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/online.boneandjoint.org.uk\/TDM"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Bone and Joint Surgery. British volume"],"published-print":{"date-parts":[[2000,4]]},"abstract":"<jats:p> Scoliosis seen in the chicken after pinealectomy resembles adolescent idiopathic scoliosis in man. It has been suggested that in both species, deficiency of the pineal hormone, melatonin, is responsible for this phenomenon. <\/jats:p><jats:p> In nine patients with adolescent idiopathic scoliosis and in ten age- and gender-matched controls, the circadian levels of serum melatonin and the excretion of urinary 6-hydroxy-melatonin-sulphate, the principal metabolite of melatonin, were determined. There were no statistically significant differences in the secretion of serum melatonin or the excretion of urinary 6-hydroxy-melatonin-sulphate between the patients and the control group. The hypothesis of melatonin deficiency as a causative factor in the aetiology of adolescent idiopathic scoliosis cannot be supported by our data. <\/jats:p>","DOI":"10.1302\/0301-620x.82b3.0820399","type":"journal-article","created":{"date-parts":[[2018,2,21]],"date-time":"2018-02-21T11:50:08Z","timestamp":1519213808000},"page":"399-403","source":"Crossref","is-referenced-by-count":94,"title":["Melatonin and adolescent idiopathic scoliosis"],"prefix":"10.1302","volume":"82-B","author":[{"given":"W.","family":"Brodner","sequence":"first","affiliation":[{"name":"Department of Orthopaedics"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Krepler","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Nicolakis","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Langer","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Vienna General Hospital, University of Vienna Medical School, W\u00e4hringer G\u00fcrtel 18-20, A-1090 Vienna, Austria."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Kaider","sequence":"additional","affiliation":[{"name":"Department of Medical Computer Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Lack","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Krankenhaus der Barmherzigen Schwestern, Stumpergasse 13, A-1060 Vienna, Austria."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Waldhauser","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Vienna General Hospital, University of Vienna Medical School, W\u00e4hringer G\u00fcrtel 18-20, A-1090 Vienna, Austria."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"42","container-title":["The Journal of Bone and Joint Surgery. British volume"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/pdf\/10.1302\/0301-620X.82B3.0820399","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/pdf\/10.1302\/0301-620X.82B3.0820399","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T19:23:02Z","timestamp":1629141782000},"score":1,"resource":{"primary":{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/10.1302\/0301-620X.82B3.0820399"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,4]]},"references-count":0,"aliases":["10.1302\/0301-620x.82b3.10208","10.1302\/0301-620x.82b3.10208"],"journal-issue":{"issue":"3","published-print":{"date-parts":[[2000,4]]}},"alternative-id":["10.1302\/0301-620X.82B3.0820399"],"URL":"https:\/\/doi.org\/10.1302\/0301-620x.82b3.0820399","relation":{},"ISSN":["0301-620X","2044-5377"],"issn-type":[{"value":"0301-620X","type":"print"},{"value":"2044-5377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,4]]}}}