{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T09:53:51Z","timestamp":1767174831808,"version":"build-2238731810"},"reference-count":0,"publisher":"British Editorial Society of Bone & Joint Surgery","issue":"3","license":[{"start":{"date-parts":[[2000,4,1]],"date-time":"2000-04-01T00:00:00Z","timestamp":954547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/online.boneandjoint.org.uk\/TDM"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Bone and Joint Surgery. British volume"],"published-print":{"date-parts":[[2000,4]]},"abstract":"<jats:p>Cleidocranial dysplasia (CCD) is inherited as an autosomal dominant disorder characterised by failure of membranous ossification. The condition is due to a mutation of the cbfa1 gene on chromosome 6 which has a role in the development of osteoblasts from the mesenchymal cells. In their growing years, these patients have an unusual shape of the femoral head reminiscent of a \u2018chef\u2019s hat\u2019. In order to confirm the consistency of this sign, we have reviewed the radiographs of 28 patients with CCD. All except three had this appearance. The sign was also seen in patients with coxa vara associated with a variety of other conditions. The chef\u2019s hat sign may occur secondary to the particular mechanical environment created by coxa vara as well as abnormal cellular function in patients with CCD. Although coxa vara has some influence on the shape of the femoral head, it is not entirely responsible for its morphology since it was present in only six of the 28 patients with CCD.<\/jats:p>","DOI":"10.1302\/0301-620x.82b3.0820404","type":"journal-article","created":{"date-parts":[[2018,2,21]],"date-time":"2018-02-21T06:50:08Z","timestamp":1519195808000},"page":"404-408","source":"Crossref","is-referenced-by-count":13,"title":["The \u2018chef\u2019s hat\u2019 appearance of the femoral head in cleidocranial dysplasia"],"prefix":"10.1302","volume":"82-B","author":[{"given":"S.","family":"Aktas","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery and Traumatology, Trakya University Faculty of Medicine, Edirne 22030, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Wheeler","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, University of Florida, 1600 South West Archer Road, Gainesville, Florida 32610, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. D.","family":"Sussman","sequence":"additional","affiliation":[{"name":"Shriners Hospital for Children, 3101 South West Sam Jackson Park Road, Portland, Oregon 97201, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"42","container-title":["The Journal of Bone and Joint Surgery. British volume"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/pdf\/10.1302\/0301-620X.82B3.0820404","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/pdf\/10.1302\/0301-620X.82B3.0820404","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T15:23:03Z","timestamp":1629127383000},"score":1,"resource":{"primary":{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/10.1302\/0301-620X.82B3.0820404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,4]]},"references-count":0,"aliases":["10.1302\/0301-620x.82b3.9919"],"journal-issue":{"issue":"3","published-print":{"date-parts":[[2000,4]]}},"alternative-id":["10.1302\/0301-620X.82B3.0820404"],"URL":"https:\/\/doi.org\/10.1302\/0301-620x.82b3.0820404","relation":{},"ISSN":["0301-620X","2044-5377"],"issn-type":[{"value":"0301-620X","type":"print"},{"value":"2044-5377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,4]]}}}