{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T10:26:06Z","timestamp":1767176766977,"version":"build-2238731810"},"reference-count":0,"publisher":"British Editorial Society of Bone & Joint Surgery","issue":"7","license":[{"start":{"date-parts":[[2001,9,1]],"date-time":"2001-09-01T00:00:00Z","timestamp":999302400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/online.boneandjoint.org.uk\/TDM"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Bone and Joint Surgery. British volume"],"published-print":{"date-parts":[[2001,9]]},"abstract":"<jats:p>Joint replacement in HIV-positive patients remains uncommon, with most experience gained in patients with haemophilia. We analysed retrospectively the outcome of 102 replacement arthroplasties in 73 HIV-positive patients from eight specialist haemophilia centres. Of these, 91 were primary procedures. The mean age of the patients at surgery was 39 years, and the median follow-up was for five years. The overall rate of deep sepsis was 18.7% for primary procedures and 36.3% for revisions. This is a much higher rate of infection than that seen in normal populations. A total of 44% of infections resolved fully after medical and\/or surgical treatment.<\/jats:p>\n                  <jats:p>The benefits of arthroplasty in haemophilic patients are well established but the rates of complications are high. As this large study has demonstrated, high rates of infection occur, but survivorship analysis strongly suggests that most patients already diagnosed with HIV infection at the time of surgery should derive many years of symptomatic relief after a successful joint replacement. Careful counselling and education of both patients and healthcare workers before operation are therefore essential.<\/jats:p>","DOI":"10.1302\/0301-620x.83b7.0831050","type":"journal-article","created":{"date-parts":[[2018,2,21]],"date-time":"2018-02-21T14:25:04Z","timestamp":1519223104000},"page":"1050-1054","source":"Crossref","is-referenced-by-count":84,"title":["Infected joint replacements in HIV-positive patients with haemophilia"],"prefix":"10.1302","volume":"83-B","author":[{"given":"J. L.","family":"Hicks","sequence":"first","affiliation":[{"name":"Nuffield Orthopaedic Centre NHS Trust, Windmill Road, Headington, Oxford OX3 7LD, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. J.","family":"Ribbans","sequence":"additional","affiliation":[{"name":"Northampton General Hospital NHS Trust, Cliftonville, Northampton NN1 5BD, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Buzzard","sequence":"additional","affiliation":[{"name":"Newcastle Haemophilia Comprehensive Care Centre, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. S.","family":"Kelley","sequence":"additional","affiliation":[{"name":"University of North Carolina, Department of Orthopaedic Surgery, 242 Burnett-Womack, CB 7055, Chapel Hill, North Carolina 27599, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Toft","sequence":"additional","affiliation":[{"name":"Watkins Medical Centre, 225 Wickham Terrace, Brisbane 4000, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Torri","sequence":"additional","affiliation":[{"name":"Institute of Clinical Orthopaedics, 1 Via Bignami, Milan 20126, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. D.","family":"Wiedel","sequence":"additional","affiliation":[{"name":"University of Colorado Health Sciences Centre, Department of Orthopaedics, 4701 East Ninth Avenue, E203, Denver, Colorado 80262, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"York","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Rachel Forster Hospital, PO Box 1127, Strawberry Hills, Sydney, New South Wales 2012, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"42","container-title":["The Journal of Bone and Joint Surgery. British volume"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/pdf\/10.1302\/0301-620X.83B7.0831050","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/pdf\/10.1302\/0301-620X.83B7.0831050","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T15:46:16Z","timestamp":1629128776000},"score":1,"resource":{"primary":{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/10.1302\/0301-620X.83B7.0831050"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,9]]},"references-count":0,"aliases":["10.1302\/0301-620x.83b7.11242"],"journal-issue":{"issue":"7","published-print":{"date-parts":[[2001,9]]}},"alternative-id":["10.1302\/0301-620X.83B7.0831050"],"URL":"https:\/\/doi.org\/10.1302\/0301-620x.83b7.0831050","relation":{},"ISSN":["0301-620X","2044-5377"],"issn-type":[{"value":"0301-620X","type":"print"},{"value":"2044-5377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,9]]}}}