{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T13:45:00Z","timestamp":1725630300598},"reference-count":33,"publisher":"British Editorial Society of Bone & Joint Surgery","issue":"9","license":[{"start":{"date-parts":[[2005,9,1]],"date-time":"2005-09-01T00:00:00Z","timestamp":1125532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/online.boneandjoint.org.uk\/TDM"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Bone and Joint Surgery. British volume"],"published-print":{"date-parts":[[2005,9]]},"abstract":"<jats:p> We have investigated the contaminating bacteria in primary hip arthroplasty and their sensitivity to the prophylactic antibiotics currently in use. Impressions (627) of the gloved hands of the surgical team in 50 total hip arthroplasties were obtained on blood agar. The gloves were changed after draping, at intervals of 20 minutes thereafter, and before using cement. Changes were also undertaken whenever a visible puncture was detected. The culture plates were incubated at 37\u00b0C for 48 hours. Isolates were identified and tested for sensitivity to flucloxacillin, which is a recognised indicator of sensitivity to cefuroxime. They were also tested against other agents depending upon their appearance on Gram staining. <\/jats:p><jats:p> We found contamination in 57 (9%) impressions and 106 bacterial isolates. Coagulase-negative staphylococci were seen most frequently (68.9%), but we also isolated Micrococcus (12.3%), diphtheroids (9.4%), Staphylococcus aureus (6.6%) and Escherichia coli (0.9%). Of the coagulase-negative staphylococci, only 52.1% were sensitive to flucloxacillin and therefore to cefuroxime. We believe that it is now appropriate to review the relevance of prophylaxis with cefuroxime and to consider the use of other agents. <\/jats:p>","DOI":"10.1302\/0301-620x.87b9.15685","type":"journal-article","created":{"date-parts":[[2005,8,29]],"date-time":"2005-08-29T18:07:45Z","timestamp":1125338865000},"page":"1256-1258","source":"Crossref","is-referenced-by-count":22,"title":["Bacterial contaminants and antibiotic prophylaxis in total hip arthroplasty"],"prefix":"10.1302","volume":"87-B","author":[{"given":"M.","family":"Al-Maiyah","sequence":"first","affiliation":[{"name":"James Cook University Hospital, Middlesbrough, TS4 3BW, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Hill","sequence":"additional","affiliation":[{"name":"James Cook University Hospital, Middlesbrough, TS4 3BW, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Bajwa","sequence":"additional","affiliation":[{"name":"James Cook University Hospital, Middlesbrough, TS4 3BW, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Slater","sequence":"additional","affiliation":[{"name":"James Cook University Hospital, Middlesbrough, TS4 3BW, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Patil","sequence":"additional","affiliation":[{"name":"James Cook University Hospital, Middlesbrough, TS4 3BW, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Port","sequence":"additional","affiliation":[{"name":"James Cook University Hospital, Middlesbrough, TS4 3BW, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. J.","family":"Gregg","sequence":"additional","affiliation":[{"name":"James Cook University Hospital, Middlesbrough, TS4 3BW, UK."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"42","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-197209000-00020"},{"key":"R2","doi-asserted-by":"crossref","unstructured":"Fitzgerald RH Jr, Nolan DR, Ilstrup DM, et al. Deep wound sepsis following total hip arthroplasty. J Bone Joint Surg [Am] 1977;59-A:847\u201355.","DOI":"10.2106\/00004623-197759070-00001"},{"key":"R3","doi-asserted-by":"crossref","unstructured":"Ha\u2019eri GB, Wiley AM. Total hip replacement in a laminar flow environment with special reference to deep infection. Clin Orthop 1980;148:163\u20138.","DOI":"10.1097\/00003086-198005000-00025"},{"key":"R4","doi-asserted-by":"crossref","unstructured":"Howorth FH. Prevention of airborne infection during surgery. Lancet 1985;1:386\u20138.","DOI":"10.1016\/S0140-6736(85)91399-6"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800560902"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.3109\/17453677708992017"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/15.2.313"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.13.2.214"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/15.4.471"},{"key":"R10","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/161.1.41"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.76B5.8083259"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.86B2.14129"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.1179\/joc.2001.13.Supplement-2.48"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.71B5.2584258"},{"key":"R15","doi-asserted-by":"crossref","unstructured":"Mauerhan D, Nelson C, Smith D, et al. Prophylaxis infection in total joint arthroplasty: one day of cefuroxime compared with three days cefazolin. J Bone Joint Surg [Am] 1994;76-A:39\u201345.","DOI":"10.2106\/00004623-199401000-00006"},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.3109\/17453679708996689"},{"key":"R17","unstructured":"Evrard J, Mazas F, Acar J, Doyon F, Flamant R. Comparison of 2 preventive antibiotic treatments in total hip arthroplasty. Rev Chir Orthop Reparatrice Appar Mot 1985;71 (Suppl 2):37 (in French)."},{"key":"R18","doi-asserted-by":"crossref","unstructured":"Glenny AM, Song F. Antimicrobial prophylaxis in total hip replacement: a systematic review. Health Technology Assessment 1999;3:19.","DOI":"10.3310\/hta3210"},{"key":"R19","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.87B4.15744"},{"key":"R20","doi-asserted-by":"crossref","unstructured":"Young EJ, Sugarman B. Infections in prosthetic devices. Surg Clin North Am 1989; 68:167\u201380.","DOI":"10.1016\/S0039-6109(16)44438-5"},{"key":"R21","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.17.2.179"},{"key":"R22","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800510309"},{"key":"R23","doi-asserted-by":"publisher","DOI":"10.1080\/000164701317268969"},{"key":"R24","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.81B4.0810577"},{"key":"R25","doi-asserted-by":"crossref","unstructured":"Wymenga A, van Horn J, Theeuwes A, Muytjens H, Slooff T. Cefurozime for prevention of postoperative coxitis: one versus three doses tested in a randomised multicenter study of 2,651 arthroplasties. Acta Orthop Scand 1992;62:19\u201324.","DOI":"10.3109\/17453679209154842"},{"key":"R26","doi-asserted-by":"publisher","DOI":"10.1007\/BF00267725"},{"key":"R27","doi-asserted-by":"publisher","DOI":"10.1007\/BF00266514"},{"key":"R28","doi-asserted-by":"publisher","DOI":"10.1016\/S0883-5403(06)80236-6"},{"key":"R29","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-15-4-475"},{"key":"R30","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.32.8.1285"},{"key":"R31","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/38.4.747"},{"key":"R32","unstructured":"Communicable Disease Report. Detecting vancomycin intermediate Staphyloccocus aureus. CDR Weekly 1997;7:417\u201320."},{"key":"R33","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/48.1.144"}],"container-title":["The Journal of Bone and Joint Surgery. British volume"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/pdf\/10.1302\/0301-620X.87B9.15685","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/full-xml\/10.1302\/0301-620X.87B9.15685","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/pdf\/10.1302\/0301-620X.87B9.15685","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T20:14:52Z","timestamp":1629144892000},"score":1,"resource":{"primary":{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/10.1302\/0301-620X.87B9.15685"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,9]]},"references-count":33,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2005,9]]}},"alternative-id":["10.1302\/0301-620X.87B9.15685"],"URL":"https:\/\/doi.org\/10.1302\/0301-620x.87b9.15685","relation":{},"ISSN":["0301-620X","2044-5377"],"issn-type":[{"value":"0301-620X","type":"print"},{"value":"2044-5377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,9]]}}}