{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T07:55:41Z","timestamp":1781337341014,"version":"3.54.1"},"reference-count":24,"publisher":"British Editorial Society of Bone & Joint Surgery","issue":"8","license":[{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/online.boneandjoint.org.uk\/TDM"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Bone and Joint Surgery. British volume"],"published-print":{"date-parts":[[2006,8]]},"abstract":"<jats:p> In a randomised study, 28 patients with a mean age of 62.2 years (32 to 81) with osteoarthritis or avascular necrosis of the hip received either a ceramic-on-ceramic or a metal-on-metal total hip replacement. Apart from the liners the acetabular and femoral components were made of Ti-Al-Nb alloy. The serum aluminium and cobalt levels were measured before, and at one year after surgery. <\/jats:p><jats:p> The 15 patients in the ceramic-on-ceramic group had a median pre-operative aluminium level of 1.3 \u03bcg\/l (0.25 to 8.4) and a cobalt level below the detection limit. At one year the aluminium level was 1.1 \u03bcg\/l (0.25 to 2.3) and the cobalt level was 0.4 \u03bcg\/l (0.15 to 0.7). The 13 patients in the metal-on-metal group had a median pre-operative aluminium level of 1.9 \u03bcg\/l (0.25 to 4.4) and a cobalt level below the detection limit. At one year the median aluminium level was 0.9 \u03bcg\/l (0.25 to 3.9) whereas the cobalt level was 1.4 \u03bcg\/l (0.5 to 10.5). This increase in the cobalt level at one year was significant (p &lt; 0.001). <\/jats:p><jats:p> Our findings indicate that ceramic-on-ceramic bearings do not cause elevated levels of serum aluminium in the first post-operative year. <\/jats:p>","DOI":"10.1302\/0301-620x.88b8.17870","type":"journal-article","created":{"date-parts":[[2006,7,28]],"date-time":"2006-07-28T16:51:15Z","timestamp":1154105475000},"page":"1003-1005","source":"Crossref","is-referenced-by-count":23,"title":["Serum aluminium and cobalt levels after ceramic-on-ceramic and metal-on-metal total hip replacement"],"prefix":"10.1302","volume":"88-B","author":[{"given":"A.","family":"Gr\u00fcbl","sequence":"first","affiliation":[{"name":"Department of Orthopaedics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Weissinger","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, General Hospital Zwettl, Propstei 5, A-3910 Zwettl, Austria."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Brodner","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, General Hospital Krems, Mitterweg 10, A-3500 Krems an der Donau, Austria."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Gleiss","sequence":"additional","affiliation":[{"name":"Core Unit for Medical Statistics and Informatics, Medical University of Vienna, Spitalgassee 23, A-1090 Vienna, Austria."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Giurea","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Gruber","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"P\u00f6ll","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, General Hospital Zwettl, Propstei 5, A-3910 Zwettl, Austria."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Meisinger","sequence":"additional","affiliation":[{"name":"Clinical Department of Occupational Medicine, Department of Internal Medicine IV, Medical University of Vienna, W\u00e4hringer G\u00fcrtel 18-20, A-1090 Vienna, Austria."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Gottsauner-Wolf","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, General Hospital Krems, Mitterweg 10, A-3500 Krems an der Donau, Austria."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Kotz","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"42","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820110202"},{"key":"R2","unstructured":"Harris WH. 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