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However, to date there have been no studies of pineal gland glucose metabolism in patients with adolescent idiopathic scoliosis that might support this hypothesis. <\/jats:p><jats:p> We examined the excretion of urinary 6-sulfatoxyl-melatonin as well as the glucose metabolism of the pineal gland in 14 patients with an adolescent idiopathic scoliosis and compared them with those of 13 gender-matched healthy controls using F-18 fluorodeoxyglucose brain positron emission tomography. There was no significant difference in the level of urinary 6-sulfatoxyl-melatonin or pineal gland metabolism between the study and the control group. We conclude that permanent melatonin deficiency is not a causative factor in the aetiology of adolescent idiopathic scoliosis. <\/jats:p>","DOI":"10.1302\/0301-620x.89b1.18058","type":"journal-article","created":{"date-parts":[[2007,1,26]],"date-time":"2007-01-26T20:35:05Z","timestamp":1169843705000},"page":"66-71","source":"Crossref","is-referenced-by-count":24,"title":["Pineal gland metabolism in patients with adolescent idiopathic scoliosis"],"prefix":"10.1302","volume":"89-B","author":[{"given":"K. T.","family":"Suh","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. S.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Environmental Engineering, College of Engineering"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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